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Reference ranges of coagulation tests


Speer, Oliver; Schmugge, Markus; Metzger, Claudia; Albisetti, Manuela (2013). Reference ranges of coagulation tests. In: Monagle, Paul. Haemostasis: Methods and Protocols. New York: Springer, 85-96.

Abstract

Reference ranges are a set of values that correctly include most of the subjects with characteristics similar to the reference group and exclude the others. When accurate, reference ranges aid physicians to interpret results of clinical measurements and thus establish diagnosis. However, obtaining accurate reference ranges is a very demanding procedure. This chapter provides basic definitions and theories as well as a step-by-step procedure for the analysis of reference values and determination of reference ranges of coagulation, focusing on quantitative clinical laboratory assays. Preanalytical and analytical factors as well as dependence on the age influencing reference values for coagulation assays and their transference are discussed.

Abstract

Reference ranges are a set of values that correctly include most of the subjects with characteristics similar to the reference group and exclude the others. When accurate, reference ranges aid physicians to interpret results of clinical measurements and thus establish diagnosis. However, obtaining accurate reference ranges is a very demanding procedure. This chapter provides basic definitions and theories as well as a step-by-step procedure for the analysis of reference values and determination of reference ranges of coagulation, focusing on quantitative clinical laboratory assays. Preanalytical and analytical factors as well as dependence on the age influencing reference values for coagulation assays and their transference are discussed.

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Additional indexing

Item Type:Book Section, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Children's Hospital Zurich > Medical Clinic
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:2013
Deposited On:28 Jan 2014 09:47
Last Modified:07 Dec 2017 08:34
Publisher:Springer
Series Name:Methods in Molecular Biology
Number:992
ISSN:1064-3745
ISBN:978-1-62703-338-1
Publisher DOI:https://doi.org/10.1007/978-1-62703-339-8_6
PubMed ID:23546706

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