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Imaging the course of a hypoplastic cerebellum in a spina bifida newborn - Zurich Open Repository and Archive


Kronenburg, Annick; Han, Kuo Sen; Gooskens, Rob; Esposito, Giuseppe; Cochrane, Douglas; Woerdeman, Peter (2013). Imaging the course of a hypoplastic cerebellum in a spina bifida newborn. Child's Nervous System, 29(11):2131-2135.

Abstract

INTRODUCTION: We report about a spina bifida patient with myelomeningocele at the lumbar level L5, extensive Chiari malformation type II with vermal herniation reaching to C6 with downward pontine shift, and a severe hypoplastic cerebellum. Chromosomal diagnostic tests showed no abnormalities.
CASE REPORT: The infant experienced severe central apneas successfully treated with oxygen therapy and caffeine medication; functional motor level was established at L5 with sparse anal sphincter function.
DISCUSSION: After surgical intervention (myelomeningocele repair and ventriculoperitoneal shunt placement), these abnormalities significantly improved on radiological imaging; the preoperative hypoplastic, almost undetectable, cerebellum developed to a fair sized cerebellum. Apneas disappeared over time and the patient showed further developmental improvement. Herein, we illustrate and discuss the changes of the cerebellar volume before and after neurosurgical intervention.

Abstract

INTRODUCTION: We report about a spina bifida patient with myelomeningocele at the lumbar level L5, extensive Chiari malformation type II with vermal herniation reaching to C6 with downward pontine shift, and a severe hypoplastic cerebellum. Chromosomal diagnostic tests showed no abnormalities.
CASE REPORT: The infant experienced severe central apneas successfully treated with oxygen therapy and caffeine medication; functional motor level was established at L5 with sparse anal sphincter function.
DISCUSSION: After surgical intervention (myelomeningocele repair and ventriculoperitoneal shunt placement), these abnormalities significantly improved on radiological imaging; the preoperative hypoplastic, almost undetectable, cerebellum developed to a fair sized cerebellum. Apneas disappeared over time and the patient showed further developmental improvement. Herein, we illustrate and discuss the changes of the cerebellar volume before and after neurosurgical intervention.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Neurosurgery
Dewey Decimal Classification:610 Medicine & health
Language:German
Date:2013
Deposited On:13 Mar 2014 14:36
Last Modified:28 Mar 2017 10:28
Publisher:Springer
ISSN:0256-7040
Publisher DOI:https://doi.org/10.1007/s00381-013-2156-y
PubMed ID:23686389

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