Header

UZH-Logo

Maintenance Infos

Coherent diffraction and holographic imaging of individual biomolecules using low-energy electrons


Latychevskaia, Tatiana; Longchamp, Jean-Nicolas; Escher, Conrad; Fink, Hans-Werner (2013). Coherent diffraction and holographic imaging of individual biomolecules using low-energy electrons. In: Read, Randy; Urzhumtsev, Alexandre G; Lunin, Vladimir Y. Advancing Methods for Biomolecular Crystallography. Dordrecht: Springer, 331-342.

Abstract

Modern microscopy techniques are aimed at imaging an individual molecule at atomic resolution. Here we show that low-energy electrons with kinetic energies of 50–250 eV offer a possibility of overcome the problem of radiation damage, and obtaining images of individual biomolecules. Two experimental schemes for obtaining images of individual molecules – holography and coherent diffraction imaging – are discussed and compared. Images of individual molecules obtained by both techniques, using low-energy electrons, are shown.

Abstract

Modern microscopy techniques are aimed at imaging an individual molecule at atomic resolution. Here we show that low-energy electrons with kinetic energies of 50–250 eV offer a possibility of overcome the problem of radiation damage, and obtaining images of individual biomolecules. Two experimental schemes for obtaining images of individual molecules – holography and coherent diffraction imaging – are discussed and compared. Images of individual molecules obtained by both techniques, using low-energy electrons, are shown.

Statistics

Citations

Altmetrics

Downloads

2 downloads since deposited on 27 Feb 2014
0 downloads since 12 months
Detailed statistics

Additional indexing

Item Type:Book Section, refereed, original work
Communities & Collections:07 Faculty of Science > Physics Institute
Dewey Decimal Classification:530 Physics
Language:English
Date:2013
Deposited On:27 Feb 2014 08:34
Last Modified:05 Apr 2016 17:43
Publisher:Springer
Series Name:NATO Science for Peace and Security Series A: Chemistry and Biology
ISBN:978-94-007-6231-2
Publisher DOI:https://doi.org/10.1007/978-94-007-6232-9_29

Download

Preview Icon on Download
Content: Accepted Version
Filetype: PDF - Registered users only
Size: 1MB
View at publisher

TrendTerms

TrendTerms displays relevant terms of the abstract of this publication and related documents on a map. The terms and their relations were extracted from ZORA using word statistics. Their timelines are taken from ZORA as well. The bubble size of a term is proportional to the number of documents where the term occurs. Red, orange, yellow and green colors are used for terms that occur in the current document; red indicates high interlinkedness of a term with other terms, orange, yellow and green decreasing interlinkedness. Blue is used for terms that have a relation with the terms in this document, but occur in other documents.
You can navigate and zoom the map. Mouse-hovering a term displays its timeline, clicking it yields the associated documents.

Author Collaborations