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Primary hyperaldosteronism in cats: a series of seven cases


Willi, Barbara; Kook, Peter H; Quante, Saskia; Boretti, Felicitas S; Sieber-Ruckstuhl, Nadja S; Grest, Paula; Scherrer, O; Riond, Barbara; Hofmann-Lehmann, Regina; Nussberger, J; Reusch, Claudia E (2013). Primary hyperaldosteronism in cats: a series of seven cases. European Journal of Companion Animal Practice (EJCAP), 23(2):62-70.

Abstract

Primary hyperaldosteronism is a disease characterised by elevated aldosterone secretion by the adrenal glands. The present case series describes seven cats with primary hyperaldosteronism presented between 2002 and 2011. Common clinical signs were weakness, anorexia, cervical ventroflexion and blindness. All cats showed hypokalaemia. Blood pressure measurement in six cats revealed hypertension in five; four of the five cats were blind because of retinal detachment. Ultrasonographic examination showed unilateral adrenomegaly in six cats and normal adrenals in one. The serum aldosterone concentration exceeded the reference range in four cats. Five cats underwent unilateral adrenalectomy, which was without complications and led to normalisation of the electrolyte concentrations. Histological examination of the adrenal glands revealed adrenocortical adenoma in four cats and adrenocortical carcinoma in two; the cat with ultrasonographic normal adrenals had bilateral nodular adrenal hyperplasia.

Abstract

Primary hyperaldosteronism is a disease characterised by elevated aldosterone secretion by the adrenal glands. The present case series describes seven cats with primary hyperaldosteronism presented between 2002 and 2011. Common clinical signs were weakness, anorexia, cervical ventroflexion and blindness. All cats showed hypokalaemia. Blood pressure measurement in six cats revealed hypertension in five; four of the five cats were blind because of retinal detachment. Ultrasonographic examination showed unilateral adrenomegaly in six cats and normal adrenals in one. The serum aldosterone concentration exceeded the reference range in four cats. Five cats underwent unilateral adrenalectomy, which was without complications and led to normalisation of the electrolyte concentrations. Histological examination of the adrenal glands revealed adrenocortical adenoma in four cats and adrenocortical carcinoma in two; the cat with ultrasonographic normal adrenals had bilateral nodular adrenal hyperplasia.

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Additional indexing

Item Type:Journal Article, not refereed, original work
Communities & Collections:05 Vetsuisse Faculty > Institute of Veterinary Pathology
05 Vetsuisse Faculty > Veterinary Clinic > Department of Small Animals
05 Vetsuisse Faculty > Veterinary Clinic > Department of Farm Animals
Dewey Decimal Classification:570 Life sciences; biology
Language:English
Date:2013
Deposited On:27 Feb 2014 08:05
Last Modified:08 Dec 2017 04:35
Publisher:Federation of European Companion Animal Veterinary Association
ISSN:1018-2357
Additional Information:This paper originally appeared in: Schweiz. Arch.Tierheilk., December 2012, 154 (12), 529 – 537
Free access at:Related URL. An embargo period may apply.
Related URLs:http://ejcap.fecava.org/auth/edition/240958/1bf69252de9cb01406a41eeaa0bd3bc1
http://dx.doi.org/10.1024/0036-7281/a000402

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