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The distribution of fasting plasma lipid concentrations in the offspring of men with premature coronary heart disease in Europe. The EARS Study


Gutzwiller, Felix; Marti, Bernard; Knobloch, Michael; Anliker, Peter (1994). The distribution of fasting plasma lipid concentrations in the offspring of men with premature coronary heart disease in Europe. The EARS Study. International Journal of Epidemiology, 23(3):472-481.

Abstract

Fasting plasma total cholesterol, high density lipoprotein (HDL)-cholesterol, low density lipoprotein (LDL)-cholesterol and total triglyceride was measured in 682 university students with a positive paternal history of coronary heart disease before the age of 55 years and 1312 age- and sex-matched controls recruited from 14 European centres. In male subjects, significant regional differences were observed for triglyceride (P < 0.005) and HDL-cholesterol (P < 0.05) but not for total or LDL-cholesterol. In female subjects, significant regional differences were observed for triglyceride (P < 0.05) and cholesterol (P < 0.05) but not for HDL- or LDL-cholesterol. Significant differences were observed between male cases and controls for cholesterol (P < 0.005) LDL-cholesterol (P < 0.005) and triglycerides (P < 0.005) but not for HDL-cholesterol. In females a significant difference was observed between cases and controls for LDL-cholesterol (P < 0.05) but not for total cholesterol, HDL-cholesterol or triglyceride.

Abstract

Fasting plasma total cholesterol, high density lipoprotein (HDL)-cholesterol, low density lipoprotein (LDL)-cholesterol and total triglyceride was measured in 682 university students with a positive paternal history of coronary heart disease before the age of 55 years and 1312 age- and sex-matched controls recruited from 14 European centres. In male subjects, significant regional differences were observed for triglyceride (P < 0.005) and HDL-cholesterol (P < 0.05) but not for total or LDL-cholesterol. In female subjects, significant regional differences were observed for triglyceride (P < 0.05) and cholesterol (P < 0.05) but not for HDL- or LDL-cholesterol. Significant differences were observed between male cases and controls for cholesterol (P < 0.005) LDL-cholesterol (P < 0.005) and triglycerides (P < 0.005) but not for HDL-cholesterol. In females a significant difference was observed between cases and controls for LDL-cholesterol (P < 0.05) but not for total cholesterol, HDL-cholesterol or triglyceride.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Epidemiology, Biostatistics and Prevention Institute (EBPI)
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:1994
Deposited On:05 Mar 2014 16:52
Last Modified:05 Apr 2016 17:44
Publisher:Oxford University Press
ISSN:0300-5771
Free access at:Publisher DOI. An embargo period may apply.
PubMed ID:7960371

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