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Computer supported collective action


Shaw, Aaron; Zhang, Haoqi; Monroy-Hernández, Andrés; Munson, Sean; Mako Hill, Benjamin; Gerber, Elizabeth; Kinnaird, Peter; Minder, Patrick (2014). Computer supported collective action. Magazine interactions, 21(2):74-77.

Abstract

Social media has become globally ubiquitous, transforming how people are networked and mobilized. This forum explores research and applications of these new networked publics at individual, organizational, and societal levels. By using a gel mobility assay, we have shown that treatment of HeLa cells with 4-hydroxynonenal, a major product of the peroxidation of membrane lipids and an inducer of heat-shock proteins, has the same effect as heat shock in causing the appearance of a protein which binds to the sequence of DNA specific for the induction of heat-shock genes. Lipoperoxidation and heat exposure seem to share a common mechanism of specific gene activation.

Abstract

Social media has become globally ubiquitous, transforming how people are networked and mobilized. This forum explores research and applications of these new networked publics at individual, organizational, and societal levels. By using a gel mobility assay, we have shown that treatment of HeLa cells with 4-hydroxynonenal, a major product of the peroxidation of membrane lipids and an inducer of heat-shock proteins, has the same effect as heat shock in causing the appearance of a protein which binds to the sequence of DNA specific for the induction of heat-shock genes. Lipoperoxidation and heat exposure seem to share a common mechanism of specific gene activation.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:03 Faculty of Economics > Department of Informatics
Dewey Decimal Classification:000 Computer science, knowledge & systems
Language:English
Date:1 March 2014
Deposited On:10 Mar 2014 14:30
Last Modified:05 Apr 2016 17:45
Publisher:ACM
Free access at:Official URL. An embargo period may apply.
Publisher DOI:https://doi.org/10.1145/2576875
Official URL:http://dl.acm.org/citation.cfm?id=2576875
PubMed ID:2576875
Other Identification Number:merlin-id:9292

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