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Neuro-oncology in 2013: improving outcome in newly diagnosed malignant glioma


Weller, M; Wick, W (2014). Neuro-oncology in 2013: improving outcome in newly diagnosed malignant glioma. Nature Reviews. Neurology, 10(2):68-70.

Abstract

In 2013, two discoveries—that alkylating agent chemotherapy prolongs survival when added to radiotherapy for patients with anaplastic oligodendroglial tumours with 1p19q codeletion, and that bevacizumab prolongs progression-free survival in patients with newly diagnosed glioblastoma—have dominated debate in neuro-oncology. These findings could help to define new standards of care in malignant glioma.

Abstract

In 2013, two discoveries—that alkylating agent chemotherapy prolongs survival when added to radiotherapy for patients with anaplastic oligodendroglial tumours with 1p19q codeletion, and that bevacizumab prolongs progression-free survival in patients with newly diagnosed glioblastoma—have dominated debate in neuro-oncology. These findings could help to define new standards of care in malignant glioma.

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Additional indexing

Item Type:Journal Article, refereed, further contribution
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Neurology
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:2014
Deposited On:28 Apr 2014 09:46
Last Modified:05 Apr 2016 17:50
Publisher:Nature Publishing Group
ISSN:1759-4758
Publisher DOI:https://doi.org/10.1038/nrneurol.2013.268
PubMed ID:24419684

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