Header

UZH-Logo

Maintenance Infos

Frequency of eprinomectin resistance in gastrointestinal nematodes of goats in canton Berne, Switzerland - Zurich Open Repository and Archive


Murri, Sarah; Knubben-Schweizer, Gabriela; Torgerson, Paul R; Hertzberg, Hubertus (2014). Frequency of eprinomectin resistance in gastrointestinal nematodes of goats in canton Berne, Switzerland. Veterinary Parasitology, 203(1-2):114-119.

Abstract

tEprinomectin (EPN) is a member of the avermectin class of compounds and the onlyanthelmintic registered for goats in Switzerland with a zero milk withdrawal period. Theaim of the present study was to identify the actual efficacy of EPN in an area with a higherdensity of goat enterprises. Forty-three randomly chosen farms from canton Berne wereinvestigated. At least eight goats were investigated on every farm. Conditions for inclusionin the study were the absence of anthelmintic treatment during the previous six weeksand a pooled faecal sample showing a mean faecal egg count (FEC) higher than 600 epgfaeces. Pre- and 14–16 days post-treatment samples were individually collected directlyfrom the rectum. Animals were treated with the recommended dose of EPN (1 mg/kg bodyweight) after taking the pre-treatment samples. Efficacy of EPN was tested with the faecalegg count reduction test (FECRT) and faecal cultures were performed on every farm frompooled faeces samples before and after treatment. Additionally the farmers completed aquestionnaire. None of the gastrointestinal nematode populations of the 43 investigatedfarms were susceptible to EPN at the required level. The mean egg count reduction was40%. None of the typical risk factors, such as production type, stocking rate, animal trafficand quarantine measures showed an association with the level of eprinomectin resistance.It can be concluded with 80% certainty that the prevalence of EPN resistance on goat farmsis at least 95% in canton Berne.

Abstract

tEprinomectin (EPN) is a member of the avermectin class of compounds and the onlyanthelmintic registered for goats in Switzerland with a zero milk withdrawal period. Theaim of the present study was to identify the actual efficacy of EPN in an area with a higherdensity of goat enterprises. Forty-three randomly chosen farms from canton Berne wereinvestigated. At least eight goats were investigated on every farm. Conditions for inclusionin the study were the absence of anthelmintic treatment during the previous six weeksand a pooled faecal sample showing a mean faecal egg count (FEC) higher than 600 epgfaeces. Pre- and 14–16 days post-treatment samples were individually collected directlyfrom the rectum. Animals were treated with the recommended dose of EPN (1 mg/kg bodyweight) after taking the pre-treatment samples. Efficacy of EPN was tested with the faecalegg count reduction test (FECRT) and faecal cultures were performed on every farm frompooled faeces samples before and after treatment. Additionally the farmers completed aquestionnaire. None of the gastrointestinal nematode populations of the 43 investigatedfarms were susceptible to EPN at the required level. The mean egg count reduction was40%. None of the typical risk factors, such as production type, stocking rate, animal trafficand quarantine measures showed an association with the level of eprinomectin resistance.It can be concluded with 80% certainty that the prevalence of EPN resistance on goat farmsis at least 95% in canton Berne.

Citations

6 citations in Web of Science®
5 citations in Scopus®
Google Scholar™

Altmetrics

Downloads

2 downloads since deposited on 22 May 2014
0 downloads since 12 months
Detailed statistics

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:05 Vetsuisse Faculty > Institute of Parasitology
04 Faculty of Medicine > Institute of Parasitology

05 Vetsuisse Faculty > Chair in Veterinary Epidemiology
Dewey Decimal Classification:570 Life sciences; biology
610 Medicine & health
600 Technology
Language:English
Date:2014
Deposited On:22 May 2014 09:32
Last Modified:05 Apr 2016 17:53
Publisher:Elsevier
ISSN:0304-4017
Publisher DOI:https://doi.org/10.1016/j.vetpar.2014.02.052
PubMed ID:24661808

Download

Preview Icon on Download
Content: Published Version
Filetype: PDF - Registered users only
Size: 586kB
View at publisher

TrendTerms

TrendTerms displays relevant terms of the abstract of this publication and related documents on a map. The terms and their relations were extracted from ZORA using word statistics. Their timelines are taken from ZORA as well. The bubble size of a term is proportional to the number of documents where the term occurs. Red, orange, yellow and green colors are used for terms that occur in the current document; red indicates high interlinkedness of a term with other terms, orange, yellow and green decreasing interlinkedness. Blue is used for terms that have a relation with the terms in this document, but occur in other documents.
You can navigate and zoom the map. Mouse-hovering a term displays its timeline, clicking it yields the associated documents.

Author Collaborations