Header

UZH-Logo

Maintenance Infos

Risk of thromboembolic events with endovascular cooling catheters in patients with subarachnoid hemorrhage


Müller, Achim; Lorenz, Andreas; Seifert, Burkhardt; Keller, Emanuela (2014). Risk of thromboembolic events with endovascular cooling catheters in patients with subarachnoid hemorrhage. Neurocritical Care, 21(2):207-210.

Abstract

INTRODUCTION: Endovascular cooling is currently used for hypothermia treatment and fever reduction therapy. At the same time, little is known about the risks associated to endovascular cooling in patients treated with an endovascular cooling catheter (ECC).
METHODS: A retrospective chart review of 122 patients with subarachnoid hemorrhage (SAH) treated with an ECC either for therapeutic hypothermia or for fever reduction was performed. ECC-associated thromboembolic events (TEE) such as pulmonary embolism and thrombosis were recorded and compared between patients treated with an ECC and patients treated only with a central venous line (CVL). Additionally, various laboratory parameters were recorded to determine if they might be related to the frequency of TEE's.
RESULTS: 43 Patients were treated with an ECC and 79 with a CVL. Patients in the ECC group suffered more frequently from TEE (37 %) than those with a CVL (5 %). None of the laboratory parameters was associated with an increased TEE risk. The treatment with an ECC alone was a risk factor for a TEE, independent from age as well as from Hunt and Hess grade.
CONCLUSION: Our data show that the treatment with ECC increases the risk of TEE in SAH patients. Therefore, especially when considered for fever reduction, non-invasive devices for surface cooling should be the first choice.

Abstract

INTRODUCTION: Endovascular cooling is currently used for hypothermia treatment and fever reduction therapy. At the same time, little is known about the risks associated to endovascular cooling in patients treated with an endovascular cooling catheter (ECC).
METHODS: A retrospective chart review of 122 patients with subarachnoid hemorrhage (SAH) treated with an ECC either for therapeutic hypothermia or for fever reduction was performed. ECC-associated thromboembolic events (TEE) such as pulmonary embolism and thrombosis were recorded and compared between patients treated with an ECC and patients treated only with a central venous line (CVL). Additionally, various laboratory parameters were recorded to determine if they might be related to the frequency of TEE's.
RESULTS: 43 Patients were treated with an ECC and 79 with a CVL. Patients in the ECC group suffered more frequently from TEE (37 %) than those with a CVL (5 %). None of the laboratory parameters was associated with an increased TEE risk. The treatment with an ECC alone was a risk factor for a TEE, independent from age as well as from Hunt and Hess grade.
CONCLUSION: Our data show that the treatment with ECC increases the risk of TEE in SAH patients. Therefore, especially when considered for fever reduction, non-invasive devices for surface cooling should be the first choice.

Statistics

Citations

Altmetrics

Downloads

16 downloads since deposited on 14 Jul 2014
12 downloads since 12 months
Detailed statistics

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Epidemiology, Biostatistics and Prevention Institute (EBPI)
04 Faculty of Medicine > University Hospital Zurich > Clinic for Neurosurgery
Dewey Decimal Classification:610 Medicine & health
Uncontrolled Keywords:Therapeutic hypothermia, subarachnoid haemorrhage, stroke, endovascular cooling, endovascular cooling catheter, thromboembolic event, thrombosis, pulmonary embolism
Language:English
Date:2014
Deposited On:14 Jul 2014 06:41
Last Modified:08 Dec 2017 22:30
Publisher:Humana Press (Springer)
ISSN:1541-6933
Additional Information:The original publication is available at www.springerlink.com
Publisher DOI:https://doi.org/10.1007/s12028-014-0001-0
PubMed ID:24962892

Download

Download PDF  'Risk of thromboembolic events with endovascular cooling catheters in patients with subarachnoid hemorrhage'.
Preview
Content: Accepted Version
Filetype: PDF
Size: 151kB
View at publisher