Header

UZH-Logo

Maintenance Infos

Nationwide time trends in dispensed prescriptions of psychotropic medication for children and adolescents in Denmark


Steinhausen, H-C; Bisgaard, C (2014). Nationwide time trends in dispensed prescriptions of psychotropic medication for children and adolescents in Denmark. Acta Psychiatrica Scandinavica, 129(3):221-231.

Abstract

OBJECTIVE
The analysis of time trends in dispensed prescriptions of psychotropic medications for children and adolescents in Denmark.

METHOD
The entire data set of the Danish prescription register covering stimulants, antidepressants, antipsychotics, and anxiolytics used in children and adolescents over a 15-year time span from 1996 to 2010 was analyzed. Both non-adjusted age-standardized prevalence rates and adjusted age-standardized prevalence rates considering the increase in patient numbers over time were calculated, and time trends were assessed based on 105908 patient-years.

RESULTS
For stimulants, antidepressants, and antipsychotics, the non-adjusted prevalence rates increased significantly. These trends were strongest for the stimulants. However, all adjusted prevalence rates were much lower with the anxiolytics even declining significantly. The prevalence rates of stimulants and antipsychotics were significantly higher among males than females, whereas females received significantly more antidepressants. The increase in prescription rates for both antidepressants and antipsychotics was mainly due to increased use among the 14- to 17-year-olds. Stratification by diagnoses revealed significantly increasing prevalence rates of dispensed antidepressants and antipsychotics in six major diagnostic indications.

CONCLUSION
Although increasing, the unadjusted Danish prevalence rates of dispensed prescriptions of psychotropics for children and adolescents are still lower than in many other Western countries.

Abstract

OBJECTIVE
The analysis of time trends in dispensed prescriptions of psychotropic medications for children and adolescents in Denmark.

METHOD
The entire data set of the Danish prescription register covering stimulants, antidepressants, antipsychotics, and anxiolytics used in children and adolescents over a 15-year time span from 1996 to 2010 was analyzed. Both non-adjusted age-standardized prevalence rates and adjusted age-standardized prevalence rates considering the increase in patient numbers over time were calculated, and time trends were assessed based on 105908 patient-years.

RESULTS
For stimulants, antidepressants, and antipsychotics, the non-adjusted prevalence rates increased significantly. These trends were strongest for the stimulants. However, all adjusted prevalence rates were much lower with the anxiolytics even declining significantly. The prevalence rates of stimulants and antipsychotics were significantly higher among males than females, whereas females received significantly more antidepressants. The increase in prescription rates for both antidepressants and antipsychotics was mainly due to increased use among the 14- to 17-year-olds. Stratification by diagnoses revealed significantly increasing prevalence rates of dispensed antidepressants and antipsychotics in six major diagnostic indications.

CONCLUSION
Although increasing, the unadjusted Danish prevalence rates of dispensed prescriptions of psychotropics for children and adolescents are still lower than in many other Western countries.

Statistics

Citations

30 citations in Web of Science®
29 citations in Scopus®
Google Scholar™

Altmetrics

Downloads

0 downloads since deposited on 16 Sep 2014
0 downloads since 12 months

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Psychiatric University Hospital Zurich > Center for Child and Adolescent Psychiatry
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:March 2014
Deposited On:16 Sep 2014 14:34
Last Modified:05 Apr 2016 18:22
Publisher:Wiley-Blackwell Publishing, Inc.
ISSN:0001-690X
Publisher DOI:https://doi.org/10.1111/acps.12155
PubMed ID:23738593

Download