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Health technology assessment in evolution - focal therapy in localised prostate cancer


Valerio, Massimo; Emberton, Mark; Barret, Eric; Eberli, Daniel; Eggener, Scott E; Ehdaie, Behfar; Jichlinski, Patrice; Ward, John F; Ahmed, Hashim U (2014). Health technology assessment in evolution - focal therapy in localised prostate cancer. Expert Review of Anticancer Therapy, 14(11):1359-1367.

Abstract

Focal therapy in prostate cancer aims to treat only the part of the gland harboring clinically significant disease while preserving the rest of the tissue. This approach may substantially reduce treatment-related toxicity without compromising disease control outcomes. Short- to medium-term functional and oncological results in prospective interventional studies are promising, but comparative effectiveness research against standard of care is required to incorporate focal therapy among standard options. In this review, we discuss the actual stage of assessment and results of sources of energy commonly used to deliver focal therapy. We also provide our viewpoint on how the field will evolve in the near future.

Abstract

Focal therapy in prostate cancer aims to treat only the part of the gland harboring clinically significant disease while preserving the rest of the tissue. This approach may substantially reduce treatment-related toxicity without compromising disease control outcomes. Short- to medium-term functional and oncological results in prospective interventional studies are promising, but comparative effectiveness research against standard of care is required to incorporate focal therapy among standard options. In this review, we discuss the actual stage of assessment and results of sources of energy commonly used to deliver focal therapy. We also provide our viewpoint on how the field will evolve in the near future.

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5 citations in Scopus®
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Additional indexing

Item Type:Journal Article, refereed, further contribution
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Urological Clinic
Dewey Decimal Classification:610 Medicine & health
Date:25 June 2014
Deposited On:01 Oct 2014 15:36
Last Modified:08 Dec 2017 07:17
Publisher:Expert Reviews
ISSN:1473-7140
Publisher DOI:https://doi.org/10.1586/14737140.2014.932692
PubMed ID:24965212

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