Fernandez, F J; de Vries, D; Peña-Soler, E; Coll, M; Christen, P; Gehring, H; Vega, M C (2012). Structure and mechanism of a cysteine sulfinate desulfinase engineered on the aspartate aminotransferase scaffold. Biochimica et Biophysica Acta, 1824(2):339-349.
Wu, F; Christen, P; Gehring, H (2011). A novel approach to inhibit intracellular vitamin B6-dependent enzymes: proof of principle with human and plasmodium ornithine decarboxylase and human histidine decarboxylase. FASEB Journal, 25(7):2109-2122.
Leemann-Zakaryan, R P; Pahlich, S; Grossenbacher, D; Gehring, H (2011). Tyrosine phosphorylation in the C-terminal nuclear localization and retention signal (C-NLS) of the EWS protein. Sarcoma, 2011:ID 218483.
Pahlich, S; Quero, L; Roschitzki, B; Leemann-Zakaryan, R P; Gehring, H (2009). Analysis of Ewing Sarcoma (EWS)-Binding Proteins: Interaction with hnRNP M, U, and RNA-Helicases p68/72 within Protein-RNA Complexes. Journal of Proteome Research, 8(10):4455-4465.
Leemann-Zakaryan, R P; Pahlich, S; Sedda, M; Quero, L; Grossenbacher, D; Gehring, H (2009). Dynamic subcellular localization of the EWS proto-oncoprotein and its association with and stabilization of microtubules. Journal of Molecular Biology, 386(1):1-13.
Müller, I B; Wu, F; Bergmann, B; Knöckel, J; Walter, R D; Gehring, H; Wrenger, C (2009). Poisoning pyridoxal 5-phosphate-dependent enzymes: a new strategy to target the malaria parasite Plasmodium falciparum. PLoS ONE, 4(2):e4406.
Wu, F; Gehring, H (2009). Structural requirements for novel coenzyme-substrate derivatives to inhibit intracellular ornithine decarboxylase and cell proliferation. FASEB Journal, 23(2):565-574.
Wu, F; Yu, J; Gehring, H (2008). Inhibitory and structural studies of novel coenzyme-substrate analogs of human histidine decarboxylase. FASEB Journal, 22(3):890-897.
Curioni-Fontecedro, A; Knights, A J; Tinguely, M; Nuber, N; Schneider, C; Thomson, C W; von Boehmer, I; Bossart, W; Pahlich, S; Gehring, H; Moch, H; Renner, C; Knuth, A; Zippelius, A (2008). MAGE-C1/CT7 is the dominant cancer-testis antigen targeted by humoral immune responses in patients with multiple myeloma. Leukemia, 22(8):1646-1648.
Pahlich, S; Zakaryan, R; Gehring, H (2008). Identification of proteins interacting with protein arginine methyltransferase 8: The Ewing sarcoma (EWS) protein binds independent of its methylation state. Proteins, 72(4):1125-1137.
Wu, F; Grossenbacher, D; Gehring, H (2007). New transition state-based inhibitor for human ornithine decarboxylase inhibits growth of tumor cells. Molecular Cancer Therapeutics, 6(6):1831-1839.
Zakaryan, R P; Gehring, H (2006). Identification and characterization of the nuclear localization/retention signal in the EWS proto-oncoprotein. Journal of Molecular Biology, 363(1):27-38.
Pahlich, S; Zakaryan, R P; Gehring, H (2006). Protein arginine methylation: Cellular functions and methods of analysis. Biochimica et Biophysica Acta, 1764(12):1890-1903.
Pahlich, S; Bschir, K; Chiavi, C; Belyanskaya, L L; Gehring, H (2005). Different methylation characteristics of protein arginine methyltransferase 1 and 3 toward the Ewing Sarcoma protein and a peptide. Proteins, 61(1):164-175.
Fernandez, F J; Vega, M C; Lehmann, F; Sandmeier, E; Gehring, H; Christen, P; Wilmanns, M (2004). Structural studies of the catalytic reaction pathway of a hyperthermophilic histidinol-phosphate aminotransferase. Journal of Biological Chemistry, 279(20):21478-21488.
Gygi, D J; Zumstein, P; Grossenbacher, D; Altwegg, L; Lüscher, T F; Gehring, H (2003). Human connective tissue growth factor expressed in Escherichia coli is a non-mitogenic inhibitor of apoptosis. Biochemical and Biophysical Research Communications (BBRC), 311(3):685-690.
Belyanskaya, L L; Delattre, O; Gehring, H (2003). Expression and subcellular localization of Ewing sarcoma (EWS) protein is affected by the methylation process. Experimental Cell Research, 288(2):374-381.
Minder, D; Böni, J; Schüpbach, J; Gehring, H (2002). Immunophilins and HIV-1 infection. Archives of Virology, 147(8):1531-1542.
Belyanskaya, L L; Gehrig, P M; Gehring, H (2001). Exposure on cell surface and extensive arginine methylation of ewing sarcoma (EWS) protein. Journal of Biological Chemistry, 276(22):18681-18687.
Kasper, P; Christen, P; Gehring, H (2000). Empirical calculation of the relative free energies of peptide binding to the molecular chaperone DnaK. Proteins, 40(2):185-192.
Graber, R; Kasper, P; Malashkevich, V N; Strop, P; Gehring, H; Jansonius, J N; Christen, P (1999). Conversion of aspartate aminotransferase into an L-aspartate beta-decarboxylase by a triple active-site mutation. Journal of Biological Chemistry, 274(44):31203-1325.
Endrich, M M; Gehrig, P; Gehring, H (1999). Maturation-induced conformational changes of HIV-1 capsid protein and identification of two high affinity sites for cyclophilins in the C-terminal domain. Journal of Biological Chemistry, 274(9):5326-5332.
Mouratou, B; Kasper, P; Gehring, H; Christen, P (1999). Conversion of tyrosine phenol-lyase to dicarboxylic amino acid beta-lyase, an enzyme not found in nature. Journal of Biological Chemistry, 274(3):1320-1325.
Endrich, M M; Gehring, H (1998). The V3 loop of human immunodeficiency virus type-1 envelope protein is a high-affinity ligand for immunophilins present in human blood. FEBS Journal, 252(3):441-446.
Kasper, P; Sterk, M; Christen, P; Gehring, H (1996). Molecular-dynamics simulation of domain movements in aspartate aminotransferase. FEBS Journal, 240(3):751-755.
Christen, P; Kasper, P; Gehring, H; Sterk, M (1996). Stereochemical constraint in the evolution of pyridoxal-5'-phosphate-dependent enzymes. A hypothesis. FEBS Letters, 389(1):12-14.
Endrich, M M; Grossenbacher, D; Geistlich, A; Gehring, H (1996). Apoptosis-induced concomitant release of cytosolic proteins and factors which prevent cell death. Biology of the Cell, 88(1-2):15-22.
Graber, R; Kasper, P; Malashkevich, V N; Sandmeier, E; Berger, P; Gehring, H; Jansonius, J N; Christen, P (1995). Changing the reaction specificity of a pyridoxal-5'-phosphate-dependent enzyme. FEBS Journal, 232(2):686-690.
Malashkevich, V N; Jäger, J; Ziak, M; Sauder, U; Gehring, H; Christen, P; Jansonius, J N (1995). Structural basis for the catalytic activity of aspartate aminotransferase K258H lacking the pyridoxal 5'-phosphate-binding lysine residue. Biochemistry, 34(2):405-414.