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Number of items: 31.

Kramer, Lovro; Renko, Miha; Završnik, Janja; Turk, Dušan; Seeger, Markus A; Vasiljeva, Olga; Grütter, Markus G; Turk, Vito; Turk, Boris (2017). Non-invasive in vivo imaging of tumour-associated cathepsin B by a highly selective inhibitory DARPin. Theranostics, 7(11):2806-2821.

Spalinger, Marianne R; Kasper, Stephanie; Gottier, Claudia; Lang, Silvia; Atrott, Kirstin; Vavricka, Stephan R; Scharl, Sylvie; Gutte, Petrus M; Grütter, Markus G; Beer, Hans-Dietmar; Contassot, Emmanuel; Chan, Andrew C; Dai, Xuezhi; Rawlings, David J; Mair, Florian; Becher, Burkhard; Falk, Werner; Fried, Michael; Rogler, Gerhard; Scharl, Michael (2016). NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22. Journal of Clinical Investigation, 126(5):1783-1800.

Reichen, Christian; Madhurantakam, Chaithanya; Hansen, Simon; Grütter, Markus G; Plückthun, Andreas; Mittl, Peer R E (2016). Structures of designed armadillo-repeat proteins show propagation of inter-repeat interface effects. Acta Crystallographica. Section D: Structural Biology, 72(Pt 1):168-175.

Spalinger, Marianne R; Kasper, Stephanie; Gottier, Claudia; Lang, Silvia; Atrott, Kirstin; Vavricka, Stephan R; Scharl, Sylvie; Raselli, Tina; Frey-Wagner, Isabelle; Gutte, Petrus M; Grütter, Markus G; Beer, Hans-Dietmar; Contassot, Emmanuel; Chan, Andrew C; Dai, Xuezhi; Rawlings, David J; Mair, Florian; Becher, Burkhard; Falk, Werner; Fried, Michael; Rogler, Gerhard; Scharl, Michael (2016). Corrigendum - NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22. Journal of Clinical Investigation, 126(11):4388.

Zwerger, Monika; Roschitzki-Voser, Heidi; Zbinden, Reto; Denais, Celine; Herrmann, Harald; Lammerding, Jan; Grütter, Markus G; Medalia, Ohad (2015). Altering lamina assembly reveals lamina-dependent and -independent functions for A-type lamins. Journal of Cell Science, 128(19):3607-3620.

Bukowska, Magdalena A; Hohl, Michael; Geertsma, Eric R; Hürlimann, Lea M; Grütter, Markus G; Seeger, Markus A (2015). A Transporter Motor Taken Apart: Flexibility in the Nucleotide Binding Domains of a Heterodimeric ABC Exporter. Biochemistry, 54(19):3086-3099.

Weinert, Christopher; Morger, Damien; Djekic, Aleksandra; Grütter, Markus G; Mittl, Peer R E (2015). Crystal structure of TRIM20 C-terminal coiled-coil/B30.2 fragment: implications for the recognition of higher order oligomers. Scientific Reports, 5:10819.

Hohl, Michael; Hürlimann, Lea M; Böhm, Simon; Schöppe, Jendrik; Grütter, Markus G; Bordignon, Enrica; Seeger, Markus A (2014). Structural basis for allosteric cross-talk between the asymmetric nucleotide binding sites of a heterodimeric ABC exporter. Proceedings of the National Academy of Sciences of the United States of America, 111(30):11025-11030.

Flütsch, Andreas; Ackermann, Rafael; Schroeder, Thilo; Lukarska, Maria; Hausammann, Georg J; Weinert, Christopher; Briand, Christophe; Grütter, Markus G (2014). Combined inhibition of caspase 3 and caspase 7 by two highly selective DARPins slows down cellular demise. Biochemical Journal, 461(2):279-290.

Flütsch, Andreas; Schroeder, Thilo; Barandun, Jonas; Ackermann, Rafael; Bühlmann, Martin; Grütter, Markus G (2014). Specific targeting of human caspases using designed ankyrin repeat proteins. Biological Chemistry, 395(10):1243-1252.

Gutte, Petrus G M; Jurt, Simon; Grütter, Markus G; Zerbe, Oliver (2014). Unusual structural features revealed by the solution NMR structure of the NLRC5 caspase recruitment domain. Biochemistry, 53(19):3106-3117.

Hausammann, Georg J; Grütter, Markus G (2013). Chimeric hERG channels containing a tetramerization domain are functional and stable. Biochemistry, 52(51):9237-9245.

Seeger, Markus A; Zbinden, Reto; Flütsch, Andreas; Gutte, Petrus G M; Engeler, Sibylle; Roschitzki-Voser, Heidi; Grütter, Markus G (2013). Design, construction, and characterization of a second-generation DARPin library with reduced hydrophobicity. Protein Science, 22(9):1239-57.

Dreier, Birgit; Honegger, Annemarie; Hess, Christian; Nagy-Davidescu, Gabriela; Mittl, Peer R E; Grütter, Markus G; Belousova, Natalya; Mikheeva, Galina; Krasnykh, Victor; Plückthun, Andreas (2013). Development of a generic adenovirus delivery system based on structure-guided design of bispecific trimeric DARPin adapters. Proceedings of the National Academy of Sciences of the United States of America, 110(10):E869-E877.

Hausammann, Georg J; Heitkamp, Thomas; Matile, Hugues; Gsell, Bernard; Thoma, Ralf; Schmid, Georg; Frasson, David; Sievers, Martin; Hennig, Michael; Grütter, Markus G (2013). Generation of an antibody toolbox to characterize hERG. Biochemical and Biophysical Research Communications, 431(1):70-75.

Bukowska, Magdalena A; Grütter, Markus G (2013). New concepts and aids to facilitate crystallization. Current Opinion in Structural Biology, 23(3):409-416.

Blomberg, Rebecca; Kries, Hajo; Pinkas, Daniel M; Mittl, Peer R E; Grütter, Markus G; Privett, Heidi K; Mayo, Stephen L; Hilvert, Donald (2013). Precision is essential for efficient catalysis in an evolved Kemp eliminase. Nature, 503(7476):418-421.

Schroeder, Thilo; Barandun, Jonas; Flütsch, Andreas; Briand, Christophe; Mittl, Peer R E; Grütter, Markus G (2013). Specific inhibition of caspase-3 by a competitive DARPin: molecular mimicry between native and designed inhibitors. Structure, 21(2):277-289.

Kebbel, Fabian; Kurz, Mareike; Arheit, Marcel; Grütter, Markus G; Stahlberg, Henning (2013). Structure and substrate-induced conformational changes of the secondary citrate/Sodium symporter CitS revealed by electron crystallography. Structure, 21(7):1243-1250.

Bonnet, Mariette; Kurz, Mareike; Mesa, Socorro; Briand, Christophe; Hennecke, Hauke; Grütter, Markus G (2013). The structure of Bradyrhizobium japonicum transcription factor FixK2 unveils sites of DNA binding and oxidation. Journal of Biological Chemistry, 288(20):14238-14246.

Mittal, Anshumali; Böhm, Simon; Grütter, Markus G; Bordignon, Enrica; Seeger, Markus A (2012). Asymmetry in the homodimeric ABC transporter MsbA recognized by a DARPin. Journal of Biological Chemistry, 287(24):20395-20406.

Merz, Tobias; Heck, Tobias; Geueke, Birgit; Mittl, Peer R E; Briand, Christophe; Seebach, Dieter; Kohler, Hans-Peter E; Grütter, Markus G (2012). Autoproteolytic and Catalytic Mechanisms for the β-Aminopeptidase BapA-A Member of the Ntn Hydrolase Family. Structure, 20(11):1850-1860.

Heck, Tobias; Merz, Tobias; Reimer, Artur; Seebach, Dieter; Rentsch, Daniel; Briand, Christophe; Grütter, Markus G; Kohler, Hans-Peter E; Geueke, Birgit (2012). Crystal Structures of BapA Complexes with β-Lactam-Derived Inhibitors Illustrate Substrate Specificity and Enantioselectivity of β-Aminopeptidases. ChemBioChem, 13(14):2137-215.

Hohl, Michael; Briand, Christophe; Grütter, Markus G; Seeger, Markus A (2012). Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation. Nature Structural and Molecular Biology, 19(4):395-402.

Roschitzki-Voser, Heidi; Schroeder, Thilo; Lenherr, Esther D; Frölich, Franziska; Schweizer, Andreas; Donepudi, Mrudula; Ganesan, Rajkumar; Mittl, Peer R E; Baici, Antonio; Grütter, Markus G (2012). Human caspases in vitro: expression, purification and kinetic characterization. Protein Expression and Purification, 84(2):236-246.

Kebbel, Fabian; Kurz, Mareike; Grütter, Markus G; Stahlberg, Henning (2012). Projection structure of the secondary citrate/sodium symporter CitS at 6 Å resolution by electron crystallography. Journal of Molecular Biology, 418(1-2):117-126.

Crespo, Maria D; Puorger, Chasper; Schärer, Martin A; Eidam, Oliv; Grütter, Markus G; Capitani, Guido; Glockshuber, Rudi (2012). Quality control of disulfide bond formation in pilus subunits by the chaperone FimC. Nature Chemical Biology, 8(8):707-713.

Madhurantakam, Chaithanya; Varadamsetty, Gautham; Grütter, Markus G; Plückthun, Andreas; Mittl, Peer R E (2012). Structure-based optimization of designed Armadillo-repeat proteins. Protein Science, 21(7):1015-1028.

Grütter, Markus G; Luban, Jeremy (2012). TRIM5 structure, HIV-1 capsid recognition, and innate immune signaling. Current Opinion in Virology, 2(2):142-150.

Eicher, Thomas; Cha, Hi-jea; Seeger, Markus A; Brandstätter, Lorenz; El-Delik, Jasmin; Bohnert, Jürgen A; Kern, Winfried V; Verrey, François; Grütter, Markus G; Diederichs, Kay; Pos, Klaas M (2012). Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 109(15):5687-5692.

Seeger, Markus A; Mittal, Anshumali; Velamakanni, Saroj; Hohl, Michael; Schauer, Stefan; Salaa, Ihsene; Grütter, Markus G; van Veen, Hendrik W (2012). Tuning the drug efflux activity of an ABC transporter in vivo by in vitro selected DARPin binders. PLoS ONE, 7(6):e37845.

This list was generated on Sun Nov 19 18:08:51 2017 CET.