UZH-Logo

Maintenance Infos

Browse by Creators - Zurich Open Repository and Archive

Navigate back| Up a level
Export as
Number of items: 13.

Hobbie, S N; Kaiser, M; Schmidt, S; Shcherbakov, D; Janusic, T; Brun, R; Böttger, E C (2011). Genetic reconstruction of protozoan rRNA decoding sites provides a rationale for paromomycin activity against Leishmania and Trypanosoma. PLoS Neglected Tropical Diseases, 5(5):e1161.

Akshay, S; Bertea, M; Hobbie, S N; Oettinghaus, B; Shcherbakov, D; Böttger, E C; Akbergenov, R (2011). Phylogenetic sequence variations in bacterial rRNA affect species-specific susceptibility to drugs targeting protein synthesis. Antimicrobial Agents and Chemotherapy, 55(9):4096-4102.

Kalapala, S K; Hobbie, S N; Böttger, E C; Shcherbakov, D (2010). Mutation K42R in ribosomal protein S12 does not affect susceptibility of Mycobacterium smegmatis 16S rRNA A-site mutants to 2-deoxystreptamines. PLoS ONE, 5(9):e11960.

Long, K S; Munck, C; Andersen, T B M; Schaub, M A; Hobbie, S N; Böttger, E C; Vester, B (2010). Mutations in 23S rRNA at the peptidyl transferase center and their relationship to linezolid binding and cross-resistance. Antimicrobial Agents and Chemotherapy, 54(11):4705-4713.

Long, K S; Poehlsgaard, J; Hansen, L H; Hobbie, S N; Böttger, E C; Vester, B (2009). Single 23S rRNA mutations at the ribosomal peptidyl transferase centre confer resistance to valnemulin and other antibiotics in Mycobacterium smegmatis by perturbation of the drug binding pocket. Molecular Microbiology, 71(5):1218-1227.

Collin, M P; Hobbie, S N; Böttger, E C; Vasella, A (2009). Synthesis and Evaluation of S- and C(1)-Substituted Analogues of Lincomycin. Helvetica Chimica Acta, 92(2):230-266.

Hobbie, S N; Subramanian, A; Kalapala, S K; Bruell, C M; Shcherbakov, D; Böttger, E C (2008). Genetic analysis of interactions with eukaryotic rRNA identify the mitoribosome as target in aminoglycoside ototoxicity. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 105(52):20888-20893.

Bruell, C M; Eichholz, C; Kubarenko, A; Post, V; Katunin, V I; Hobbie, S N; Rodnina, M V; Böttger, E C (2008). Conservation of bacterial protein synthesis machinery: initiation and elongation in Mycobacterium smegmatis. Biochemistry, 47(34):8828-8839.

Hobbie, S N; Bruell, C M; Akshay, S; Kalapala, S K; Shcherbakov, D; Böttger, E C (2008). Mitochondrial deafness alleles confer misreading of the genetic code. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 105(9):3244-3249.

Collin, M P; Hobbie, S N; Böttger, E C; Vasella, A (2008). Synthesis of 1,2,3-triazole analogues of lincomycin. Helvetica Chimica Acta, 91(10):1838-1848.

Hobbie, S N; Kalapala, S K; Akshay, S; Bruell, C M; Schmidt, S; Dabow, S; Vasella, A; Sander, P; Böttger, E C (2007). Engineering the rRNA decoding site of eukaryotic cytosolic ribosomes in bacteria. Nucleic Acids Research, 35(18):6086-6093.

Hobbie, S N; Bruell, C; Kalapala, S; Akshay, S; Schmidt, S; Pfister, P; Böttger, E C (2006). A genetic model to investigate drug-target interactions at the ribosomal decoding site. Biochimie, 88(8):1033-1043.

Hobbie, S N; Pfister, P; Bruell, C; Sander, P; François, B; Westhof, E; Böttger, E C (2006). Binding of neomycin-class aminoglycoside antibiotics to mutant ribosomes with alterations in the A site of 16S rRNA. Antimicrobial Agents and Chemotherapy, 50(4):1489-1496.

This list was generated on Sat Jul 22 01:45:45 2017 CEST.