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Number of items: 36.

Alecu, Irina; Othman, Alaa; Penno, Anke; Saied, Essa M; Arenz, Christoph; von Eckardstein, Arnold; Hornemann, Thorsten (2017). Cytotoxic 1-deoxysphingolipids are metabolized by a cytochrome P450-dependent pathway. Journal of Lipid Research, 58(1):60-71.

Nowak, Albina; Boesch, Lukas; Andres, Erik; Battegay, Edouard; Hornemann, Thorsten; Schmid, Christoph; Bischoff-Ferrari, Heike A; Suter, Paolo M; Krayenbuehl, Pierre-Alexandre (2016). Effect of vitamin D3 on self-perceived fatigue: A double-blind randomized placebo-controlled trial. Medicine, 95(52):e5353.

Zhakupova, Assem; Debeuf, Nincy; Krols, Michiel; Toussaint, Wendy; Vanhoutte, Leen; Alecu, Irina; Kutalik, Zoltán; Vollenweider, Peter; Ernst, Daniela; von Eckardstein, Arnold; Lambrecht, Bart N; Janssens, Sophie; Hornemann, Thorsten (2016). ORMDL3 expression levels have no influence on the activity of serine palmitoyltransferase. FASEB Journal, 30(12):4289-4300.

Laaksonen, Reijo; Ekroos, Kim; Sysi-Aho, Marko; Hilvo, Mika; Vihervaara, Terhi; Kauhanen, Dimple; Suoniemi, Matti; Hurme, Reini; März, Winfried; Scharnagl, Hubert; Stojakovic, Tatjana; Vlachopoulou, Efthymia; Lokki, Marja-Liisa; Nieminen, Markku S; Klingenberg, Roland; Matter, Christian M; Hornemann, Thorsten; Jüni, Peter; Rodondi, Nicolas; Räber, Lorenz; Windecker, Stephan; Gencer, Baris; Pedersen, Eva Ringdal; Tell, Grethe S; Nygård, Ottar; Mach, Francois; Sinisalo, Juha; Lüscher, Thomas F (2016). Plasma ceramides predict cardiovascular death in patients with stable coronary artery disease and acute coronary syndromes beyond LDL-cholesterol. European Heart Journal, 37(25):1967-1976.

Steiner, Regula; Saied, Essa M; Othman, Alaa; Arenz, Christoph; Maccarone, Alan T; Poad, Berwyck L J; Blanksby, Stephen J; von Eckardstein, Arnold; Hornemann, Thorsten (2016). Elucidating the chemical structure of native 1-deoxysphingosine. Journal of Lipid Research, 57(7):1194-1203.

Forny, Patrick; Schumann, Anke; Mustedanagic, Merima; Mathis, Déborah; Wulf, Marie-Angela; Nägele, Nadine; Langhans, Claus-Dieter; Zhakupova, Assem; Heeren, Joerg; Scheja, Ludger; Fingerhut, Ralph; Peters, Heidi L; Hornemann, Thorsten; Thony, Beat; Kölker, Stefan; Burda, Patricie; Froese, D Sean; Devuyst, Olivier; Baumgartner, Matthias R (2016). Novel mouse models of methylmalonic aciduria recapitulate phenotypic traits with a genetic dosage effect. Journal of Biological Chemistry, 291(39):20563-20573.

Ziv, Carmit; Malitsky, Sergey; Othman, Alaa; Ben-Dor, Shifra; Wei, Yu; Zheng, Shuning; Aharoni, Asaph; Hornemann, Thorsten; Vardi, Assaf (2016). Viral serine palmitoyltransferase induces metabolic switch in sphingolipid biosynthesis and is required for infection of a marine alga. Proceedings of the National Academy of Sciences of the United States of America, 113(13):1907-1916.

Sutter, Iryna; Klingenberg, Roland; Othman, Alaa; Rohrer, Lucia; Landmesser, Ulf; Heg, Dierik; Rodondi, Nicolas; Mach, Francois; Windecker, Stephan; Matter, Christian M; Lüscher, Thomas F; von Eckardstein, Arnold; Hornemann, Thorsten (2016). Decreased phosphatidylcholine plasmalogens--A putative novel lipid signature in patients with stable coronary artery disease and acute myocardial infarction. Atherosclerosis, 246:130-140.

Güntert, Tanja; Hänggi, Pascal; Othman, Alaa; Suriyanarayanan, Saranya; Sonda, Sabrina; Zuellig, Richard A; Hornemann, Thorsten; Ogunshola, Omolara O (2016). 1-Deoxysphingolipid-induced neurotoxicity involves N-methyl-d-aspartate receptor signaling. Neuropharmacology, 110:211-222.

Nowak, Albina; Boesch, Lukas; Andres, Erik; Battegay, Edouard; Hornemann, Thorsten; Schmid, Christoph; Bischoff-Ferrari, Heike A; Suter, Paolo M; Krayenbuehl, Pierre-Alexandre (2016). Effect of vitamin D3 on self-perceived fatigue. Medicine, 95(52):e5353.

Bode, Heiko; Bourquin, Florence; Suriyanarayanan, Saranya; Wei, Yu; Alecu, Irina; Othman, Alaa; von Eckardstein, Arnold; Hornemann, Thorsten (2016). HSAN1 mutations in serine palmitoyltransferase reveal a close structure-function-phenotype relationship. Human Molecular Genetics, 25(5):853-865.

Köhler, Ulrike A; Böhm, Friederike; Rolfs, Frank; Egger, Michèle; Hornemann, Thorsten; Pasparakis, Manolis; Weber, Achim; Werner, Sabine (2016). NF-κB/RelA and Nrf2 cooperate to maintain hepatocyte integrity and to prevent development of hepatocellular adenoma. Journal of Hepatology, 64(1):94-102.

Suriyanarayanan, Saranya; Auranen, Mari; Toppila, Jussi; Paetau, Anders; Shcherbii, Maria; Palin, Eino; Wei, Yu; Lohioja, Tarja; Schlotter-Weigel, Beate; Schön, Ulrike; Abicht, Angela; Rautenstrauss, Bernd; Tyynismaa, Henna; Walter, Maggie C; Hornemann, Thorsten; Ylikallio, Emil (2016). The Variant p.(Arg183Trp) in SPTLC2 Causes Late-Onset Hereditary Sensory Neuropathy. Neuromolecular Medicine, 18(1):81-90.

Hornemann, Thorsten (2015). CME-Labor 43: Alkoholische (ASH) und nicht-alkoholische Fettleber (NASH). Praxis, 104(23):1247-1248.

Kramer, Rita; Bielawski, Jacek; Kistner-Griffin, Emily; Othman, Alaa; Alecu, Irina; Ernst, Daniela; Kornhauser, Drew; Hornemann, Thorsten; Spassieva, Stefka (2015). Neurotoxic 1-deoxysphingolipids and paclitaxel-induced peripheral neuropathy. FASEB Journal, 29(11):4461-72.

Sutter, Iryna; Velagapudi, Srividya; Othman, Alaa; Riwanto, Meliana; Manz, Jasmin; Rohrer, Lucia; Rentsch, Katharina; Hornemann, Thorsten; Landmesser, Ulf; von Eckardstein, Arnold (2015). Plasmalogens of high-density lipoproteins (HDL) are associated with coronary artery disease and anti-apoptotic activity of HDL. Atherosclerosis, 241(2):539-546.

Othman, Alaa; Saely, Christoph H; Muendlein, Axel; Vonbank, Alexander; Drexel, Heinz; von Eckardstein, Arnold; Hornemann, Thorsten (2015). Plasma C20-Sphingolipids predict cardiovascular events independently from conventional cardiovascular risk factors in patients undergoing coronary angiography. Atherosclerosis, 240(1):216-221.

Ernst, Daniela; Murphy, Sinéad M; Sathiyanadan, Karthik; Wei, Yu; Othman, Alaa; Laurá, Matilde; Liu, Yo-Tsen; Penno, Anke; Blake, Julian; Donaghy, Michael; Houlden, Henry; Reilly, Mary M; Hornemann, Thorsten (2015). Novel HSAN1 mutation in serine palmitoyltransferase resides at a putative phosphorylation site that is involved in regulating substrate specificity. Neuromolecular Medicine, 17(1):47-57.

Lou, Phing-How; Lucchinetti, Eliana; Zhang, Liyan; Affolter, Andreas; Gandhi, Manoj; Zhakupova, Assem; Hersberger, Martin; Hornemann, Thorsten; Clanachan, Alexander S; Zaugg, Michael (2015). Propofol (Diprivan®) and Intralipid® Exacerbate Insulin Resistance in Type-2 Diabetic Hearts by Impairing GLUT4 Trafficking. Anesthesia and Analgesia, 120(2):329-340.

Astudillo, Leonardo; Sabourdy, Frédérique; Therville, Nicole; Bode, Heiko; Ségui, Bruno; Andrieu-Abadie, Nathalie; Hornemann, Thorsten; Levade, Thierry (2015). Human genetic disorders of sphingolipid biosynthesis. Journal of Inherited Metabolic Disease, 38(1):65-76.

Hornemann, Thorsten (2015). CME-Labor 43/Auflösung: Alkoholische (ASH) und nicht-alkoholische Fettleber (NASH). Praxis, 104(24):1353-1355.

Othman, Alaa; Benghozi, Renee; Alecu, Irina; Wei, Yu; Niesor, Eric; von Eckardstein, Arnold; Hornemann, Thorsten (2015). Fenofibrate lowers atypical sphingolipids in plasma of dyslipidemic patients: A novel approach for treating diabetic neuropathy? Journal of Clinical Lipidology, 9(4):568-575.

Othman, Alaa; Bianchi, Roberto; Alecu, Irina; Wei, Yu; Porretta-Serapiglia, Carla; Lombardi, Raffaella; Chiorazzi, Alessia; Meregalli, Cristina; Oggioni, Norberto; Cavaletti, Guido; Lauria, Giuseppe; von Eckardstein, Arnold; Hornemann, Thorsten (2015). Lowering plasma 1-Deoxysphingolipids improves neuropathy in diabetic rats. Diabetes, 64(3):1035-1045.

Hornemann, Thorsten (2015). Palmitoylation and depalmitoylation defects. Journal of Inherited Metabolic Disease, 38(1):179-186.

Othman, Alaa; Saely, Christoph H; Muendlein, Axel; Vonbank, Alexander; Drexel, Heinz; von Eckardstein, Arnold; Hornemann, Thorsten (2015). Plasma 1-deoxysphingolipids are predictive biomarkers for type 2 diabetes mellitus. BMJ Open Diabetes Research and Care, 3(1):e000073.

Wei, Nancy; Pan, Jessica; Pop-Busui, Rodica; Othman, Alaa; Alecu, Irina; Hornemann, Thorsten; Eichler, Florian S (2014). Altered sphingoid base profiles in type 1 compared to type 2 diabetes. Lipids in Health and Disease, 13(161):online.

Sutter, Iryna; Park, Rebekka; Othman, Alaa; Rohrer, Lucia; Hornemann, Thorsten; Stoffel, Markus; Devuyst, Olivier; von Eckardstein, Arnold (2014). Apolipoprotein M modulates erythrocyte efflux and tubular reabsorption of sphingosine-1-phosphate. Journal of Lipid Research, 55(8):1730-1737.

Hornemann, Thorsten (2014). CME-Labor 34 : Tumormarker für Vorsorgeuntersuchungen. Praxis, 103(5):255-256.

Hornemann, Thorsten (2014). CME-Labor 34/Auflösung : Tumormarker für Vorsorgeuntersuchungen. Praxis, 103(6):353-354.

Zuellig, Richard A; Hornemann, Thorsten; Othman, Alaa; Hehl, Adrian B; Bode, Heiko; Güntert, Tanja; Ogunshola, Omolara O; Saponara, Enrica; Grabliauskaite, Kamile; Jang, Jae-Hwi; Ungethuem, Udo; Wei, Yu; von Eckardstein, Arnold; Graf, Rolf; Sonda, Sabrina (2014). Deoxysphingolipids, a novel biomarker for type 2 diabetes, are cytotoxic for insulin-producing cells. Diabetes, 63(4):1326-1339.

Murphy, Sinéad M; Ernst, Daniela; Wei, Yu; Laurà, Matilde; Liu, Yo-Tsen; Polke, James; Blake, Julian; Winer, John; Houlden, Henry; Hornemann, Thorsten; Reilly, Mary M (2013). Hereditary sensory and autonomic neuropathy type 1 (HSANI) caused by a novel mutation in SPTLC2. Neurology, 80(23):2106-2111.

Auer-Grumbach, Michaela; Bode, Heiko; Pieber, Thomas R; Schabhüttl, Maria; Fischer, Dirk; Seidl, Rainer; Graf, Elisabeth; Wieland, Thomas; Schuh, Reinhard; Vacariu, Gerda; Grill, Franz; Timmerman, Vincent; Strom, Tim M; Hornemann, Thorsten (2013). Mutations at Ser331 in the HSN type I gene SPTLC1 are associated with a distinct syndromic phenotype. European Journal of Medical Genetics, 56(5):266-269.

Hornemann, Thorsten; Worgall, Tilla S (2013). Sphingolipids and atherosclerosis. Atherosclerosis, 226(1):16-28.

Conen, David; Adam, Martin; Roche, Frederic; Barthelemy, Jean-Claude; Felber Dietrich, Denise; Imboden, Medea; Künzli, Nino; von Eckardstein, Arnold; Regenass, Stephan; Hornemann, Thorsten; Rochat, Thierry; Gaspoz, Jean-Michel; Probst-Hensch, Nicole; Carballo, David (2012). Premature atrial contractions in the general population: frequency and risk factors. Circulation, 126(19):2302-2308.

Hornemann, Thorsten. Serine-Palmitoyltransferase – New aspects of an old enzyme. 2011, University of Zurich, Faculty of Science.

Hornemann, Thorsten; Wei, Yu; von Eckardstein, Arnold (2007). Is the mammalian serine palmitoyltransferase a high-molecular-mass complex? Biochemical Journal, 405(1):157-164.

This list was generated on Fri Sep 22 01:45:10 2017 CEST.