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Number of items: 51.

Wang, C; Qu, C; Alippe, Y; Bonar, S L; Civitelli, R; Abu-Amer, Y; Hottiger, M O; Mbalaviele, G (2016). Poly-ADP-ribosylation-mediated degradation of ARTD1 by the NLRP3 inflammasome is a prerequisite for osteoclast maturation. Cell Death and Disease, 7(3):e2153.

Bluwstein, A; Kumar, N; Léger, K; Traenkle, J; van Oostrum, J; Rehrauer, H; Baudis, M; Hottiger, M O (2013). PKC signaling prevents irradiation-induced apoptosis of primary human fibroblasts. Cell Death and Disease, 4:e498.

Hottiger, M O (2011). ADP-ribosylation of histones by ARTD1: an additional module of the histone code? FEBS Letters, 585(11):1595-1599.

Toller, I M; Neelsen, K J; Steger, M; Hartung, M L; Hottiger, M O; Stucki, M; Kalali, B; Gerhard, M; Sartori, A A; Lopes, M; Müller, A (2011). Carcinogenic bacterial pathogen Helicobacter pylori triggers DNA double-strand breaks and a DNA damage response in its host cells. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 108(36):14944-14949.

Chen, Y; Wang, H; Yoon, S O; Xu, X; Hottiger, M O; Svaren, J; Nave, K A; Kim, H A; Olson, E N; Lu, Q R (2011). HDAC-mediated deacetylation of NF-κB is critical for Schwann cell myelination. Nature Neuroscience, 14(4):437-441.

Messner, S; Hottiger, M O (2011). Histone ADP-ribosylation in DNA repair, replication and transcription. Trends in Cell Biology, 21(9):534-542.

Rosenthal, F; Messner, S; Roschitzki, B; Gehrig, P; Nanni, P; Hottiger, M O (2011). Identification of distinct amino acids as ADP-ribose acceptor sites by mass spectrometry. Methods in Molecular Biology, 780(Part 1):57-66.

Hottiger, M O (2011). Mehr als nur synthetische Lethalität mit BRCA1/2. Vet-MedReport, 38(V4):4.

Valovka, T; Hottiger, M O (2011). P65 controls NF-κB activity by regulating cellular localization of IκBβ. Biochemical Journal, 434(2):253-263.

Gebhard, C; Stähli, B E; Shi, Y; Camici, G G; Akhmedov, A; Hoegger, L; Lohmann, C; Matter, C M; Hassa, P O; Hottiger, M O; Malinski, T; Lüscher, T F; Tanner, F C (2011). Poly(ADP-ribose) polymerase-1 protects from oxidative stress induced endothelial dysfunction. Biochemical and Biophysical Research Communications (BBRC), 414(4):641-646.

Hottiger, M O; Boothby, M; Koch-Nolte, F; Lüscher, B; Martin, N M B; Plummer, R; Wang, Z Q; Ziegler, M (2011). Progress in the function and regulation of ADP-Ribosylation. Science Signaling, 4(174):mr5.

Niederer, F; Ospelt, C; Brentano, F; Hottiger, M O; Gay, R E; Gay, S; Detmar, M; Kyburz, D (2011). SIRT1 overexpression in the rheumatoid arthritis synovium contributes to proinflammatory cytokine production and apoptosis resistance. Annals of the Rheumatic Diseases, 70(10):1866-1873.

Asher, G; Reinke, H; Altmeyer, M; Gutierrez-Arcelus, M; Hottiger, M O; Schibler, U (2010). Poly(ADP-ribose) polymerase 1 participates in the phase entrainment of circadian clocks to feeding. Cell, 142(6):943-953.

Altmeyer, M; Barthel, M; Eberhard, M; Rehrauer, H; Hardt, W D; Hottiger, M O (2010). Absence of poly(ADP-ribose) polymerase 1 delays the onset of Salmonella enterica serovar Typhimurium-induced gut inflammation. Infection and Immunity, 78(8):3420-3431.

Toller, I M; Altmeyer, M; Kohler, E; Hottiger, M O; Müller, A (2010). Inhibition of ADP ribosylation prevents and cures helicobacter-induced gastric preneoplasia. Cancer Research, 70(14):5912-5922.

Messner, S; Altmeyer, M; Zhao, H; Pozivil, A; Roschitzki, B; Gehrig, P; Rutishauser, D; Huang, D; Caflisch, A; Hottiger, M O (2010). PARP1 ADP-ribosylates lysine residues of the core histone tails. Nucleic Acids Research, 38(19):6350-6362.

Rothgiesser, K M; Fey, M; Hottiger, M O (2010). Acetylation of p65 at lysine 314 is important for late NF-kappaB-dependent gene expression. BMC Genomics, 11:22.

Stein, S; Lohmann, C; Schäfer, N; Hofmann, J; Rohrer, L; Besler, C; Rothgiesser, K M; Becher, B; Hottiger, M O; Borén, J; McBurney, M W; Landmesser, U; Lüscher, T F; Matter, C M (2010). SIRT1 decreases Lox-1-mediated foam cell formation in atherogenesis. European Heart Journal, 31(18):2301-2309.

Rothgiesser, K M; Erener, S; Waibel, S; Lüscher, B; Hottiger, M O (2010). SIRT2 regulates NF-κB dependent gene expression through deacetylation of p65 Lys310. Journal of Cell Science, 123(Pt 24):4251-4258.

Guetg, C; Lienemann, P; Sirri, V; Grummt, I; Hernandez-Verdun, D; Hottiger, M O; Fussenegger, M; Santoro, R (2010). The NoRC complex mediates the heterochromatin formation and stability of silent rRNA genes and centromeric repeats. The EMBO Journal, 29(13):2135-2146.

Hottiger, M O; Hassa, P O; Lüscher, B; Schüler, H; Koch-Nolte, F (2010). Toward a unified nomenclature for mammalian ADP-ribosyltransferases. Trends in Biochemical Sciences, 35(4):208-219.

Dietschy, T; Shevelev, I; Pena-Diaz, J; Hühn, D; Kuenzle, S; Mak, R; Miah, M F; Hess, D; Fey, M; Hottiger, M O; Janscak, P; Stagljar, I (2009). p300-mediated acetylation of the Rothmund-Thomson-syndrome gene product RECQL4 regulates its subcellular localization. Journal of Cell Science, 122(Pt. 8):1258-1267.

Chapman, S W; Metzger, N; Grest, P; Feige, K; von Rechenberg, B; Auer, J A; Hottiger, M O (2009). Isolation, establishment, and characterization of ex vivo equine melanoma cell cultures. In Vitro Cellular & Developmental Biology - Animal, 45(3-4):152-162.

Timinszky, G; Till, S; Hassa, P O; Hothorn, M; Kustatscher, G; Nijmeijer, B; Colombelli, J; Altmeyer, M; Stelzer, E H K; Scheffzek, K; Hottiger, M O; Ladurner, A G (2009). A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation. Nature Structural and Molecular Biology, 16(9):923-929.

Jayne, S; Rothgiesser, K M; Hottiger, M O (2009). CARM1 but not its enzymatic activity is required for transcriptional coactivation of NF-kappaB-dependent gene expression. Journal of Molecular Biology, 394(3):485-495.

Altmeyer, M; Messner, S; Hassa, P O; Fey, M; Hottiger, M O (2009). Molecular mechanism of poly(ADP-ribosyl)ation by PARP1 and identification of lysine residues as ADP-ribose acceptor sites. Nucleic Acids Research, 37(11):3723-3738.

Altmeyer, M; Hottiger, M O (2009). Poly(ADP-ribose) polymerase 1 at the crossroad of metabolic stress and inflammation in aging. Aging, 1(5):458-469.

Rajamohan, S B; Pillai, V B; Gupta, M; Sundaresan, N R; Birukov, K G; Samant, S; Hottiger, M O; Gupta, M P (2009). SIRT1 promotes cell survival under stress by deacetylation-dependent deactivation of poly(ADP-ribose) polymerase 1. Molecular and Cellular Biology, 29(15):4116-4129.

Messner, S; Schuermann, D; Altmeyer, M; Kassner, I; Schmidt, D; Schär, P; Müller, S; Hottiger, M O (2009). Sumoylation of poly(ADP-ribose) polymerase 1 inhibits its acetylation and restrains transcriptional coactivator function. FASEB Journal, 23(11):3978-3989.

Haenni, S S; Altmeyer, M; Hassa, P O; Valovka, T; Fey, M; Hottiger, M O (2008). Importin alpha binding and nuclear localization of PARP-2 is dependent on lysine 36, which is located within a predicted classical NLS. BMC Cell Biology, 9:39.

Kamau Chapman, S; Hassa, P; Koch, S; von Rechenberg, Brigitte; Hofmann-Amtenbrink, M; Steitz, B; Petri-Fink, A; Hofmann, H; Hottiger, M O (2008). Application of pulsed magnetic field enhances non-viral gene delivery in primary cells from different origins. Journal of Magnetism and Magnetic Materials, 320(8):1517-1527.

Hassa, P O; Covic, M; Bedford, M T; Hottiger, M O (2008). Protein arginine methyltransferase 1 coactivates NF-kappaB-dependent gene expression synergistically with CARM1 and PARP1. Journal of Molecular Biology, 377(3):668-678.

Buerki, C; Rothgiesser, K M; Valovka, T; Owen, H R; Rehrauer, H; Fey, M; Lane, W S; Hottiger, M O (2008). Functional relevance of novel p300-mediated lysine 314 and 315 acetylation of RelA/p65. Nucleic Acids Research, 36(5):1665-1680.

Elser, M; Borsig, L; Hassa, P O; Erener, S; Messner, S; Valovka, T; Keller, S; Gassmann, M; Hottiger, M O (2008). Poly(ADP-ribose) polymerase 1 promotes tumor cell survival by coactivating hypoxia-inducible factor-1-dependent gene expression. Molecular Cancer Research, 6(2):282-290.

Hassa, P O; Hottiger, M O (2008). The diverse biological roles of mammalian PARPS, a small but powerful family of poly-ADP-ribose polymerases. Frontiers in Bioscience, 13:3046-3082.

Haenni, S S; Hassa, P O; Altmeyer, M; Fey, M; Imhof, R; Hottiger, M O (2008). Identification of lysines 36 and 37 of PARP-2 as targets for acetylation and auto-ADP-ribosylation. International Journal of Biochemistry & Cell Biology, 40(10):2274-2283.

von Lukowicz, T; Hassa, P O; Lohmann, C; Borén, J; Braunersreuther, V; Mach, F; Odermatt, B; Gersbach, M; Camici, G G; Stähli, B E; Tanner, F C; Hottiger, M O; Lüscher, T F; Matter, C M (2008). PARP1 is required for adhesion molecule expression in atherogenesis. Cardiovascular Research, 78(1):158-166.

Kleine, H; Poreba, E; Lesniewicz, K; Hassa, P O; Hottiger, M O; Litchfield, D W; Shilton, B H; Lüscher, B (2008). Substrate-assisted catalysis by PARP10 limits its activity to mono-ADP-ribosylation. Molecular Cell, 32(1):57-69.

El-Andaloussi, N; Valovka, T; Toueille, M; Hassa, P O; Gehrig, P; Covic, M; Hübscher, U; Hottiger, M O (2007). Methylation of DNA polymerase beta by protein arginine methyltransferase 1 regulates its binding to proliferating cell nuclear antigen. FASEB Journal, 21(1):26-34.

El-Andaloussi, N; Valovka, T; Toueille, M; Steinacher, R; Focke, F; Gehrig, P; Covic, M; Hassa, P O; Schär, P; Hübscher, U; Hottiger, M O (2006). Arginine methylation regulates DNA polymerase beta. Molecular Cell, 22(1):51-62.

Friedrich-Heineken, E; Toueille, M; Tännler, B; Bürki, C; Ferrari, E; Hottiger, M O; Hübscher, U (2005). The two DNA clamps Rad9/Rad1/Hus1 complex and proliferating cell nuclear antigen differentially regulate flap endonuclease 1 activity. Journal of Molecular Biology, 353(5):980-989.

Toueille, M; El-Andaloussi, N; Frouin, I; Freire, R; Funk, D; Shevelev, I V; Friedrich-Heineken, E; Villani, G; Hottiger, M O; Hübscher, U (2004). The human Rad9/Rad1/Hus1 damage sensor clamp interacts with DNA polymerase beta and increases its DNA substrate utilisation efficiency: implications for DNA repair. Nucleic Acids Research, 32(11):3316-3324.

Hasan, S; El-Andaloussi, N; Hardeland, U; Hassa, P O; Bürki, C; Imhof, R; Schär, P; Hottiger, M O (2002). Acetylation regulates the DNA end-trimming activity of DNA polymerase beta. Molecular Cell, 10(5):1213-1222.

Tasara, T; Maga, G; Hottiger, M O; Hübscher, U (2001). HIV-1 reverse transcriptase and integrase enzymes physically interact and inhibit each other. FEBS Letters, 507(1):39-44.

Tasara, T; Hottiger, M O; Hübscher, U (2001). Functional genomics in HIV-1 virus replication: protein-protein interactions as a basis for recruiting the host cell machinery for viral propagation. Biological Chemistry, 382(7):993-999.

Hasan, S; Stucki, M; Hassa, P O; Imhof, R; Gehrig, P; Hunziker, P; Hübscher, U; Hottiger, M O (2001). Regulation of human flap endonuclease-1 activity by acetylation through the transcriptional coactivator p300. Molecular Cell, 7(6):1221-1231.

Koundrioukoff, S; Jónsson, Z O; Hasan, S; de Jong, R N; van der Vliet, P C; Hottiger, M O; Hübscher, U (2000). A direct interaction between proliferating cell nuclear antigen (PCNA) and Cdk2 targets PCNA-interacting proteins for phosphorylation. Journal of Biological Chemistry, 275(30):22882-22887.

Lutz, M J; Held, H A; Hottiger, M O; Hübscher, U; Benner, S A (1996). Differential discrimination of DNA polymerase for variants of the non-standard nucleobase pair between xanthosine and 2,4-diaminopyrimidine, two components of an expanded genetic alphabet. Nucleic Acids Research, 24(7):1308-1313.

Amacker, M; Hottiger, M O; Hübscher, U (1995). Feline immunodeficiency virus reverse transcriptase: expression, functional characterization, and reconstitution of the 66- and 51-kilodalton subunits. Journal of Virology, 69(10):6273-6279.

Horlacher, J; Hottiger, M O; Podust, V N; Hübscher, U; Benner, S A (1995). Recognition by viral and cellular DNA polymerases of nucleosides bearing bases with nonstandard hydrogen bonding patterns. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 92(14):6329-6333.

Hottiger, M O; Gramatikoff, K; Georgiev, O; Chaponnier, C; Schaffner, W; Hübscher, U (1995). The large subunit of HIV-1 reverse transcriptase interacts with beta-actin. Nucleic Acids Research, 23(5):736-741.

This list was generated on Tue Sep 19 10:58:28 2017 CEST.