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Hübscher, U; Maga, G (2011). DNA replication and repair bypass machines. Current Opinion in Chemical Biology, 15(5):627-635.

DNA Polymerases Discovery,Characterizations and Functions in Cellular DNA Transactions. Edited by: Hübscher, U; Spadari, S; Villani, G; Maga, G (2010). Singapure, Singapure: World Scientific Publishing Co. PTE. Ltd..

Maga, G; van Loon, B; Crespan, E; Villani, G; Hübscher, U (2009). The block of DNA polymerase delta strand displacement activity by an abasic site can be rescued by the concerted action of DNA polymerase beta and Flap endonuclease 1. Journal of Biological Chemistry, 284(21):14267-1475.

Amoroso, A; Crespan, E; Wimmer, U; Hubscher, U; Maga, G (2008). DNA Polymerases and Oxidative Damage: Friends or Foes? Current Molecular Pharmacology, 1(2):162-170.

Maga, G; Hübscher, U (2008). Repair and Translesion DNA Polymerases as Anticancer Drug Targets. Anti-Cancer Agents in Medicinal Chemistry, 8(4):431-447.

Belousova, E A; Crespan, E; Lebedeva, N A; Rechunova, N J; Hübscher, U; Maga, G; Lavrik, O I (2008). Photoreactive DNA Probes as a Tool for Studying the Translesion Synthesis System in Mammalian Cell Extracts. Medicinal Chemistry, 4(2):155-162.

Crespan, M; Cancio, E; Spadari, S; Hübscher, U; Maga, G (2008). Selective targeting of the HIV-1 reverse transcriptase catalytic complex through interaction with the “primer grip” region by pyrrolobenzoxazepinone non-nucleoside inhibitors correlates with increased activity towards drug-resistant mutants. Biochemical Pharmacology, 76(2):156-168.

Gembka, A; Smirnova, E; Hübscher, U (2008). The checkpoint sensors, the 9-1-1 complex and the Rad17-RF-C2-5 complex: at the crossroads of DNA damage checkpoint and DNA repair. In: Maga, G; Hübscher, U; Villani, G; Baldacci, G. DNA Replication, Repair and Recombination at the Crossroad Between Genome Integrity and Genomic Instability : A Biochemical Perspective. Kerala: Research Signpost, 77-86.

Crespan, E; Hübscher, U; Maga, G (2007). Error-free bypass of 2-hydroxyadenine by human DNA polymerase lambda with Proliferating Cell Nuclear Antigen and Replication Protein A in different sequence contexts. Nucleic Acids Research, 35(15):5173-5181.

Maga, G; Amacker, M; Hübscher, U; Gosselin, G; Imbach, J L; Mathé, C; Faraj, A; Sommadossi, J P; Spadari, S (2006). Structural determinants of HIV-1 reverse transcriptase stereoselectivity towards (beta)-L-deoxy- and dideoxy-pyrimidine nucleoside triphosphates: molecular basis for the combination of L-dideoxynucleoside analogs with non-nucleoside inhibitors in anti HIV chemotherapy. Nucleosides, Nucleotides and Nucleic Acids, 18(4-5):795-805.

Maga, G; Shevelev, I V; Villani, G; Spadari, S; Hübscher, U (2006). Human replication protein A can suppress the intrinsic in vitro mutator phenotype of human DNA polymerase lambda. Nucleic Acids Research, 34(5):1405-1415.

Cancio, R; Silvestri, R; Ragno, R; Artico, M; De Martino, G; La Regina, G; Crespan, E; Zanoli, S; Hübscher, U; Spadari, S; Maga, G (2005). High potency of indolyl aryl sulfone nonnucleoside inhibitors towards drug-resistant human immunodeficiency virus type 1 reverse transcriptase mutants is due to selective targeting of different mechanistic forms of the enzyme. Antimicrobial Agents and Chemotherapy, 49(11):4546-4554.

Locatelli, G A; Di Santo, R; Crespan, E; Costi, R; Roux, A; Hübscher, U; Shevelev, I V; Blanca, G; Villani, G; Spadari, S; Maga, G (2005). Diketo hexenoic acid derivatives are novel selective non-nucleoside inhibitors of mammalian terminal deoxynucleotidyl transferases, with potent cytotoxic effect against leukemic cells. Molecular Pharmacology, 68(2):538-550.

Crespan, E; Zanoli, S; Khandazhinskaya, A; Shevelev, I V; Jasko, M; Alexandrova, L; Kukhanova, M; Blanca, G; Villani, G; Hübscher, U; Spadari, S; Maga, G (2005). Incorporation of non-nucleoside triphosphate analogues opposite to an abasic site by human DNA polymerases beta and lambda. Nucleic Acids Research, 33(13):4117-4127.

Locatelli, G A; Savio, M; Forti, L; Shevelev, I V; Ramadan, K; Stivala, L A; Vannini, V; Hübscher, U; Spadari, S; Maga, G (2005). Inhibition of mammalian DNA polymerases by resveratrol: mechanism and structural determinants. Biochemical Journal, 389(2):259-268.

Maga, G; Ramadan, K; Locatelli, G A; Shevelev, I V; Spadari, S; Hübscher, U (2005). DNA elongation by the human DNA polymerase lambda polymerase and terminal transferase activities are differentially coordinated by proliferating cell nuclear antigen and replication protein A. Journal of Biological Chemistry, 280(3):1971-1981.

Crespan, E; Locatelli, G A; Cancio, R; Hübscher, U; Spadari, S; Maga, G (2005). Drug resistance mutations in the nucleotide binding pocket of human immunodeficiency virus type 1 reverse transcriptase differentially affect the phosphorolysis-dependent primer unblocking activity in the presence of stavudine and zidovudine and its inhibition by efavirenz. Antimicrobial Agents and Chemotherapy, 49(1):342-349.

Maga, G; Blanca, G; Shevelev, I V; Frouin, I; Ramadan, K; Spadari, S; Villani, G; Hübscher, U (2004). The human DNA polymerase lambda interacts with PCNA through a domain important for DNA primer binding and the interaction is inhibited by p21/WAF1/CIP1. FASEB Journal, 18(14):1743-1745.

Blanca, G; Villani, G; Shevelev, I V; Ramadan, K; Spadari, S; Hübscher, U; Maga, G (2004). Human DNA polymerases lambda and beta show different efficiencies of translesion DNA synthesis past abasic sites and alternative mechanisms for frameshift generation. Biochemistry, 43(36):11605-11615.

Ramadan, K; Shevelev, I V; Maga, G; Hübscher, U (2004). De novo DNA synthesis by human DNA polymerase lambda, DNA polymerase mu and terminal deoxyribonucleotidyl transferase. Journal of Molecular Biology, 339(2):395-404.

Locatelli, G A; Campiani, Giuseppe; Cancio, R; Morelli, E; Ramunno, A; Gemma, S; Hübscher, U; Spadari, S; Maga, G (2004). Effects of drug resistance mutations L100I and V106A on the binding of pyrrolobenzoxazepinone nonnucleoside inhibitors to the human immunodeficiency virus type 1 reverse transcriptase catalytic complex. Antimicrobial Agents and Chemotherapy, 48(5):1570-1580.

Shevelev, I V; Blanca, G; Villani, G; Ramadan, K; Spadari, S; Hübscher, U; Maga, G (2003). Mutagenesis of human DNA polymerase lambda: essential roles of Tyr505 and Phe506 for both DNA polymerase and terminal transferase activities. Nucleic Acids Research, 31(23):6916-6925.

Maga, G; Hubscher, U (2003). Proliferating cell nuclear antigen (PCNA): a dancer with many partners. Journal of Cell Science, 116(15):3051-3060.

Baldanti, F; Paolucci, S; Maga, G; Labo, N; Hübscher, U; Skoblov, A Y; Victorova, L; Spadari, S; Minoli, L; Gerna, G (2003). Nevirapine-selected mutations Y181I/C of HIV-1 reverse transcriptase confer cross-resistance to stavudine. AIDS, 17(10):1568-1570.

Blanca, G; Shevelev, I V; Ramadan, K; Villani, G; Spadari, S; Hübscher, U; Maga, G (2003). Human DNA polymerase lambda diverged in evolution from DNA polymerase beta toward specific Mn(++) dependence: a kinetic and thermodynamic study. Biochemistry, 42(24):7467-7476.

Blanca, G; Baldanti, F; Paolucci, S; Skoblov, A Y; Victorova, L; Hübscher, U; Gerna, G; Spadari, S; Maga, G (2003). Nevirapine resistance mutation at codon 181 of the HIV-1 reverse transcriptase confers stavudine resistance by increasing nucleotide substrate discrimination and phosphorolytic activity. Journal of Biological Chemistry, 278(18):15469-15472.

Ramadan, K; Maga, G; Shevelev, I V; Villani, G; Blanco, L; Hübscher, U (2003). Human DNA polymerase lambda possesses terminal deoxyribonucleotidyl transferase activity and can elongate RNA primers: implications for novel functions. Journal of Molecular Biology, 328(1):63-72.

Maga, G; Villani, G; Ramadan, K; Shevelev, I V; Tanguy Le Gac, N; Blanco, L; Blanca, G; Spadari, S; Hübscher, U (2002). Human DNA polymerase lambda functionally and physically interacts with proliferating cell nuclear antigen in normal and translesion DNA synthesis. Journal of Biological Chemistry, 277(50):48434-48440.

Maga, G; Shevelev, I V; Ramadan, K; Spadari, S; Hübscher, U (2002). DNA polymerase theta purified from human cells is a high-fidelity enzyme. Journal of Molecular Biology, 319(2):359-369.

Ramadan, K; Shevelev, I V; Maga, G; Hübscher, U (2002). DNA polymerase lambda from calf thymus preferentially replicates damaged DNA. Journal of Biological Chemistry, 277(21):18454-18458.

Frouin, I; Montecucco, A; Biamonti, G; Hübscher, U; Spadari, S; Maga, G (2002). Cell cycle-dependent dynamic association of cyclin/Cdk complexes with human DNA replication proteins. The EMBO Journal, 21(10):2485-2495.

Pascucci, B; Maga, G; Hübscher, U; Bjoras, M; Seeberg, E; Hickson, I D; Villani, G; Giordano, C; Cellai, L; Dogliotti, E (2002). Reconstitution of the base excision repair pathway for 7,8-dihydro-8-oxoguanine with purified human proteins. Nucleic Acids Research, 30(10):2124-2130.

Hubscher, U; Maga, G; Spadari, S (2002). Eukaryotic DNA polymerases. Annual Review of Biochemistry, 71:133-163.

Maga, G; Villani, G; Tillement, V; Stucki, M; Locatelli, G A; Frouin, I; Spadari, S; Hübscher, U (2001). Okazaki fragment processing: modulation of the strand displacement activity of DNA polymerase delta by the concerted action of replication protein A, proliferating cell nuclear antigen, and flap endonuclease-1. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 98(25):14298-14303.

Maga, G; Ramunno, A; Nacci, V; Locatelli, G A; Spadari, S; Fiorini, I; Baldanti, F; Paolucci, S; Zavattoni, M; Bergamini, A; Galletti, B; Muck, S; Hubscher, U; Giorgi, G; Guiso, G; Caccia, S; Campiani, G (2001). The stereoselective targeting of a specific enzyme-substrate complex is the molecular mechanism for the synergic inhibition of HIV-1 reverse transcriptase by (R)-(-)-PPO464: a novel generation of nonnucleoside inhibitors. Journal of Biological Chemistry, 276(48):44653-44662.

Tasara, T; Maga, G; Hottiger, M O; Hübscher, U (2001). HIV-1 reverse transcriptase and integrase enzymes physically interact and inhibit each other. FEBS Letters, 507(1):39-44.

Maga, G; Frouin, I; Spadari, S; Hubscher, U (2001). Replication protein A as a "fidelity clamp" for DNA polymerase alpha. Journal of Biological Chemistry, 276(21):18235-18242.

Maga, G; Hübscher, U; Pregnolato, M; Ubiali, D; Gosselin, G; Spadari, S (2001). Potentiation of inhibition of wild-type and mutant human immunodeficiency virus type 1 reverse transcriptases by combinations of nonnucleoside inhibitors and d- and L-(beta)-dideoxynucleoside triphosphate analogs. Antimicrobial Agents and Chemotherapy, 45(4):1192-1200.

Maga, G; Stucki, M; Spadari, S; Hübscher, U (2000). DNA polymerase switching: I. Replication factor C displaces DNA polymerase alpha prior to PCNA loading. Journal of Molecular Biology, 295(4):801.

Keller, R C; Mossi, R; Maga, G; Wellinger, R E; Hübscher, U; Sogo, J M (1999). Electron microscopic analysis reveals that replication factor C is sequestered by single-stranded DNA. Nucleic Acids Research, 27(17):3433-3437.

Maga, G; Amacker, M; Hübscher, U; Gosselin, G; Imbach, J L; Mathé, C; Faraj, A; Sommadossi, J P; Spadari, S (1999). Molecular basis for the enantioselectivity of HIV-1 reverse transcriptase: role of the 3'-hydroxyl group of the L-(beta)-ribose in chiral discrimination between D- and L-enantiomers of deoxy- and dideoxy-nucleoside triphosphate analogs. Nucleic Acids Research, 27(4):972-978.

Marx, A; Spichty, M; Amacker, M; Schwitter, U; Hübscher, U; Bickle, T A; Maga, G; Giese, B (1999). Probing interactions between HIV-1 reverse transcriptase and its DNA substrate with backbone-modified nucleotides. Chemistry & Biology, 6(2):111-116.

Maga, G; Jónsson, Z O; Stucki, M; Spadari, S; Hübscher, U (1999). Dual mode of interaction of DNA polymerase epsilon with proliferating cell nuclear antigen in primer binding and DNA synthesis. Journal of Molecular Biology, 285(1):259-267.

Perderiset, M; Maga, G; Piard, K; Francesconi, S; Tratner, I; Hübscher, U; Baldacci, G (1998). Mutant DNA polymerase delta from thermosensitive Schizosaccharomyces pombe strains display reduced stimulation by proliferating cell nuclear antigen. Biochemical Journal, 335(3):581-588.

Schurtenberger, P; Egelhaaf, S U; Hindges, R; Maga, G; Jónsson, Z O; May, R P; Glatter, O; Hübscher, U (1998). The solution structure of functionally active human proliferating cell nuclear antigen determined by small-angle neutron scattering. Journal of Molecular Biology, 275(1):123-132.

Maga, G; Amacker, M; Ruel, N; Hübscher, U; Spadari, S (1997). Resistance to nevirapine of HIV-1 reverse transcriptase mutants: loss of stabilizing interactions and thermodynamic or steric barriers are induced by different single amino acid substitutions. Journal of Molecular Biology, 274(5):738-747.

Hoffmann, J S; Pillaire, M J; Maga, G; Podust, V N; Hübscher, U; Villani, G (1995). DNA polymerase beta bypasses in vitro a single d(GpG)-cisplatin adduct placed on codon 13 of the HRAS gene. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 92(12):5356-5360.

This list was generated on Tue Oct 17 22:51:27 2017 CEST.