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Number of items: 59.

Fridle, C; Medinger, M; Wilk, M C; Seipel, K; Passweg, J; Manz, M G; Pabst, T (2017). Cladribine, cytarabine and idarubicin (CLA-Ida) salvage chemotherapy in relapsed acute myeloid leukemia (AML). Leukemia & Lymphoma, 58(5):1068-1075.

Kovtonyuk, L; Fritsch, K; Feng, X; Manz, M G; Takizawa, H (2016). Inflamm-aging of hematopoiesis, hematopoietic stem cells, and the bone marrow microenvironment. Frontiers in Immunology, 7:502.

Rauch, P J; Ellegast, J M; Widmer, C C; Fritsch, K; Goede, J S; Valk, P J; Löwenberg, B; Takizawa, H; Manz, M G (2016). MPL expression on AML blasts predicts peripheral blood neutropenia and thrombocytopenia. Blood, 128(18):2253-2257.

Das, R; Srowig, T; Verma, R; Koduru, S; Hafemann, A; Hopf, S; Kocoglu, M H; Borsotti, C; Zhang, L; Branagan, A; Eynon, E; Manz, M G; Flavell, R A; Dhodapkar, M V (2016). Microenvironment-dependent growth of preneoplastic and malignant plasma cells in humanized mice. Nature Medicine, 22(11):1351-1357.

Ellegast, J M; Rauch, P J; Kovtonyuk, L V; Müller, R; Wagner, U; Saito, Y; Wildner-Verhey van Wijk, N; Fritz, C; Rafiei, A; Lysenko, V; Dudkiewicz, E; Theocharides, A P; Soldini, D; Goede, J S; Flavell, R A; Manz, M G (2016). inv(16) and NPM1$^{mut}$ AMLs engraft human cytokine knock-in mice. Blood, 128(17):2130-2134.

Luis, T C; Tremblay, C S; Manz, M G; North, T E; King, K Y; Challen, G A (2016). Inflammatory signals in HSPC development and homeostasis: Too much of a good thing? Experimental Hematology, 44(10):908-912.

Gerber, B; Alberio, L; Rochat, S; Stenner, F; Manz, M G; Buser, A; Schanz, U; Stussi, G (2016). Safety and efficacy of cryopreserved autologous platelet concentrates in HLA-alloimmunized patients with hematologic malignancies. Transfusion, 56(10):2426-2437.

Saito, Y; Ellegast, J M; Rafiei, A; Song, Y; Kull, D; Heikenwalder, M; Rongvaux, A; Halene, S; Flavell, R A; Manz, M G (2016). Peripheral blood CD34$^+$ cells efficiently engraft human cytokine knock-in mice. Blood, 128(14):1829-1833.

Kovtonyuk, L V; Manz, M G; Takizawa, H (2016). Enhanced thrombopoietin but not G-CSF receptor stimulation induces self-renewing hematopoietic stem cell divisions in vivo. Blood, 127(25):3175-3179.

Pietras, E M; Mirantes-Barbeito, C; Fong, S; Loeffler, D; Kovtonyuk, L V; Zhang, S; Lakshminarasimhan, R; Chin, C P; Techner, J M; Will, B; Nerlov, C; Steidl, U; Manz, M G; Schroeder, T; Passegué, E (2016). Chronic interleukin-1 exposure drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewal. Nature Cell Biology, 18(6):607-618.

Boettcher, S; Manz, M G (2016). Sensing and translation of pathogen signals into demand-adapted myelopoiesis. Current Opinion in Hematology, 23(1):5-10.

Versluis, J; In't Hout, F E; Devillier, R; van Putten, W L; Manz, M G; Vekemans, M C; Legdeur, M C; Passweg, J R; Maertens, J; Kuball, J; Biemond, B J; Valk, P J; van der Reijden, B A; Meloni, G; Schouten, H C; Vellenga, E; Pabst, T; Willemze, R; Löwenberg, B; Ossenkoppele, G; Baron, F; Huls, G; Cornelissen, J J (2016). Comparative value of post-remission treatment in cytogenetically normal AML subclassified by NPM1 and FLT3-ITD allelic ratio. Leukemia, 31(1):26-33.

Theocharides, A P; Rongvaux, A; Fritsch, K; Flavell, R A; Manz, M G (2016). Humanized hemato-lymphoid system mice. Haematologica, 101(1):5-19.

Ziegler, P; Boettcher, S; Takizawa, H; Manz, M G; Brümmendorf, T H (2016). LPS-stimulated human bone marrow stroma cells support myeloid cell development and progenitor cell maintenance. Annals of Hematology, 95(2):173-178.

Saito, Y; Ellegast, J M; Manz, M G (2016). Generation of humanized mice for analysis of human dendritic cells. In: Segura, Elodie; Onai, Nobuyuki. Dendritic Cell Protocols. New York: Springer, 309-320.

Gemuenden, C; Benz, R; Senn, O; Goede, J S; Manz, M G; Gerber, B (2015). Efficacy of azacitidine in de novo and relapsed acute myeloid leukemia: a retrospective comparative study. Clinical Lymphoma, Myeloma & Leukemia:811-815.

Mager, L F; Riether, C; Schürch, C M; Banz, Y; Wasmer, M H; Stuber, R; Theocharides, A P; Li, X; Xia, Y; Saito, H; Nakae, S; Baerlocher, G M; Manz, M G; McCoy, K D; Macpherson, A J; Ochsenbein, AF; Beutler, B; Krebs, P (2015). IL-33 signaling contributes to the pathogenesis of myeloproliferative neoplasms. Journal of Clinical Investigation, 125(7):2579-2591.

Berres, M L; Lim, K P; Peters, T; Price, J; Takizawa, H; Salmon, H; Idoyaga, J; Ruzo, A; Lupo, P J; Hicks, M J; Shih, A; Simko, S J; Abhyankar, H; Chakraborty, R; Leboeuf, M; Beltrao, M; Lira, S A; Heym, K M; Clausen, B E; Bigley, V; Collin, M; Manz, M G; McClain, K; Merad, M; Allen, C E (2015). Erratum for BRAF-V600E expression in precursor versus differentiated dendritic cells defines clinically distinct LCH risk groups. Journal of Experimental Medicine, 212(2):281.

Cornelissen, J J; Versluis, J; Passweg, J R; van Putten, W L; Manz, M G; Maertens, J; Beverloo, H B; Valk, P J; van Marwijk, Kooy M; Wijermans, P W; Schaafsma, M R; Biemond, B J; Vekemans, M C; Breems, D A; Verdonck, L F; Fey, M F; Jongen-Lavrencic, M; Janssen, J J; Huls, G; Kuball, J; Pabst, T; Graux, C; Schouten, H C; Gratwohl, A; Vellenga, E; Ossenkoppele, G; Löwenberg, B (2015). Comparative therapeutic value of post-remission approaches in patients with acute myeloid leukemia aged 40-60 years. Leukemia, 29(5):1041-1050.

Balmer, M L; Schürch, C M; Saito, Y; Geuking, M B; Li, H; Cuenca, M; Kovtonyuk, L V; Mc Coy, K D; Hapfelmeier, S; Ochsenbein, A F; Manz, M G; Slack, E; Mcpherson, A J (2014). Microbiota-derived compounds drive steady-state granulopoiesis via MyD88/TICAM signaling. Journal of Immunology, 193(10):5273-5283.

Lundberg, P; Takizawa, H; Kubovcakova, L; Guo, G; Hao-Shen, H; Dirnhofer, S; Orkin, S H; Manz, M G; Skoda, R C (2014). Myeloproliferative neoplasms can be initiated from a single hematopoietic stem cell expressing JAK2-V617F. Nature Cell Biology, 211(11):2213-2230.

Boettcher, S; Gerosa, R C; Radpour, R; Bauer, J; Ampenberger, F; Heikenwalder, M; Kopf, M; Manz, M G (2014). Endothelial cells translate pathogen signals into G-CSF-driven emergency granulopoiesis. Blood, 124(9):1393-1403.

Sendoel, A; Maida, S; Zheng, X; Teo, Y; Stergiou, L; Rossi, C A; Subasic, D; Pinto, S M; Kinchen, J M; Shi, M; Boettcher, S; Meyer, J N; Manz, M G; Bano, D; Hengartner, M O (2014). DEPDC1/LET-99 participates in an evolutionarily conserved pathway for anti-tubulin drug-induced apoptosis. Nature Cell Biology, 16(8):812-820.

Bolisetty, S; Boddupalli, C S; Handschin, S; Chaitanya, K; Adamcik, J; Saito, Y; Manz, M G; Mezzenga, R (2014). Amyloid fibrils enhance transport of metal nanoparticles in living cells and induced cytotoxicity. Biomacromolecules, 15(7):2793-2799.

Manz, M G; Boettcher, S (2014). Emergency granulopoiesis. Nature Reviews. Immunology, 14:302-14.

Berres, M L; Lim, K P; Peters, T; Price, J; Takizawa, H; Salmon, H; Idoyaga, J; Ruzo, A; Lupo, P J; Hicks, M J; Shih, A; Simko, S J; Abhyankar, H; Chakraborty, R; Leboeuf, M; Beltrao, M; Lira, S A; Heym, K M; Bigley, V; Collin, M; Manz, M G; McClain, K; Merad, M; Allen, C E (2014). BRAF-V600E expression in precursor versus differentiated dendritic cells defines clinically distinct LCH risk groups. Journal of Experimental Medicine, 211(4):669-683.

Strassberger, V; Gutbrodt, K L; Krall, N; Roesli, C; Takizawa, H; Manz, M G; Fugmann, T; Neri, D (2014). A comprehensive surface proteome analysis of myeloid leukemia cell lines for therapeutic antibody development. Journal of Proteomics, 99:138-151.

Sievert, H; Pällmann, N; Miller, K K; Hermanns-Borgmeyer, I; Venz, S; Sendoel, A; Preukschas, M; Schweizer, M; Boettcher, S; Janiesch, P C; Streichert, T; Walther, R; Hengartner, M O; Manz, M G; Brümmendorf, T H; Bokemeyer, C; Braig, M; Hauber, J; Duncan, K E; Balabanov, S (2014). A novel mouse model for inhibition of DOHH-mediated hypusine modification reveals a crucial function in embryonic development, proliferation and oncogenic transformation. Disease Models & Mechanisms, 7(8):963-976.

Rongvaux, A; Willinger, T; Martinek, J; Strowig, T; Gearty, S V; Teichmann, L L; Saito, Y; Marches, F; Halene, S; Palucka, A K; Manz, M G; Flavell, R A (2014). Development and function of human innate immune cells in a humanized mouse model. Nature Biotechnology, 32(4):364-372.

Wueest, S; Mueller, R; Blüher, M; Item, F; Chin, A S; Wiedemann, M S; Takizawa, H; Kovtonyuk, L; Chervonsky, A V; Schoenle, E J; Manz, M G; Konrad, D (2014). Fas (CD95) expression in myeloid cells promotes obesity-induced muscle insulin resistance. EMBO Molecular Medicine, 6(1):43-56.

Rauch, P J; Müllhaupt, B; Biedermann, L; Manz, M G; Ruschitzka, F; Flammer, A; Segerer, S T; Mohebbi, N; Jung, H H; Moch, H; Ikenberg, K; Aguzzi, A; Nuvolone, M; Distler, O; Rauch, A; Fehr, T H; Gerber, B (2014). Systemische Amyloidosen. Swiss Medical Forum, 14(50):943-948.

Hauber, I; Hofmann-Sieber, H; Chemnitz, J; Dubrau, D; Chusainow, J; Stucka, R; Hartjen, P; Schambach, A; Ziegler, P; Hackmann, K; Schröck, E; Schumacher, U; Lindner, C; Grundhoff, A; Baum, C; Manz, M G; Buchholz, F; Hauber, J (2013). Highly significant antiviral activity of HIV-1 LTR-specific tre-recombinase in humanized mice. PLoS Pathogens, 9(9):e1003587.

Saito, Y; Boddupalli, C S; Borsotti, C; Manz, M G (2013). Dendritic cell homeostasis is maintained by nonhematopoietic and T-cell-produced Flt3-ligand in steady state and during immune responses. European Journal of Immunology, 6(43):1651-1658.

Scotti, C; Piccinini, E; Takizawa, H; Todorov, A; Bourqine, P; Papadimitropoulos, A; Barbero, A; Manz, M G; Martin, I (2013). Engineering of a functional bone organ through endochondral ossification. Proceedings of the National Academy of Sciences of the United States of America, 10(110):3997-4002.

Gerull, S; Stern, M; Ben Aissa, A; Manz, M G; Schanz, U; Stussi, G; Chalandon, Y; Passweg, J; Mohty, B (2013). Allo-SCT for multiple myeloma in the era of novel agents: a retrospective study on behalf of Swiss Blood SCT. Bone Marrow Transplantation, 48(3):408-413.

Rongvaux, A; Takizawa, H; Strowig, T; Willinger, T; Eynon, E E; Flavell, R A; Manz, M G (2013). Human hemato-lymphoid system mice: current use and future potential for medicine. Annual Review of Immunology, 31:635-674.

Boettcher, S; Ziegler, P; Schmid, M A; Takizawa, H; van Rooijen, N; Kopf, M; Heikenwälder, M; Manz, M G (2012). Cutting edge: LPS-induced emergency myelopoiesis depends on TLR4-expressing nonhematopoietic cells. Journal of Immunology, 188(12):5824-5828.

Takizawa, H; Boettcher, S; Manz, M G (2012). Demand-adapted regulation of early hematopoiesis in infection and inflammation. Blood, 119(13):2991-3002.

Schmid, M A; Takizawa, H; Baumjohann, D R; Saito, Y; Manz, M G (2011). Bone marrow dendritic cell progenitors sense pathogens via toll-like receptors and subsequently migrate to inflamed lymph nodes. Blood, 118(18):4829-4840.

Rathinam, C; Poueymirou, W T; Rojas, J; Murphy, A J; Valenzuela, D M; Yancopoulus, G D; Rongvaux, A; Eynon, E E; Manz, M G; Flavell, R A (2011). Efficient differentiation and function of human macrophages in humanized CSF-1 mice. Blood, 118(11):3119-3128.

Villaudy, J; Wencker, M; Gadot, N; Gillet, N A; Scoazec, J Y; Gazzalo, L; Manz, M G; Bangham, C R; Dodon, M D (2011). HTLV-1 propels thymic human T cell development in "human immune system" Rag2⁻/⁻ gamma c⁻/⁻ mice. PLoS Pathogens, 7(9):e1002231.

Strowig, T; Rongvaux, A; Rathinam, C; Takizawa, H; Borsotti, C; Philbrick, W; Eynon, E E; Manz, M G; Flavell, R A (2011). Transgenic expression of human signal regulatory protein alpha in Rag2-/-gamma(c)-/- mice improves engraftment of human hematopoietic cells in humanized mice. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 108(32):13218-13223.

Takizawa, H; Manz, M G (2011). Dynamic regulation of hematopoietic stem cell cycling. Cell Cycle, 10(14):2246-2247.

Willinger, T; Rongvaux, A; Strowig, T; Manz, M G; Flavell, R A (2011). Improving human hemato-lymphoid-system mice by cytokine knock-in gene replacement. Trends in Immunology, 32(7):321-327.

Takizawa, H; Regoes, R R; Boddupalli, C S; Bonhoeffer, S; Manz, M G (2011). Dynamic variation in cycling of hematopoietic stem cells in steady state and inflammation. Journal of Experimental Medicine, 208(2):273-284.

Willinger, T; Rongvaux, A; Takizawa, H; Yancopoulus, G D; Valenzuela, D M; Murphy, A J; Auerbach, W; Eynon, E E; Stevens, S; Manz, M G; Flavell, R A (2011). Human IL-3/GM-CSF knock-in mice support human alveolar macrophage development and human immune responses in the lung. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 108(6):2390-2395.

Schmid, M A; Kingston, D; Boddupalli, S; Manz, M G (2010). Instructive cytokine signals in dendritic cell lineage commitment. Immunological Reviews, 234(1):32-44.

Geissmann, F; Manz, M G; Jung, S; Sieweke, M H; Merad, M; Ley, K (2010). Development of monocytes, macrophages, and dendritic cells. Science, 327(5966):656-661.

Meek, B; Cloosen, S; Borsotti, C; Van Elssen, C H; Vanderlocht, J; Schnijderberg, M C; van der Poel, M W; Leewis, B; Hesselink, R; Manz, M G; Katsura, Y; Kawamoto, H; Germeraad, W T; Bos, G M (2010). In vitro-differentiated T/natural killer-cell progenitors derived from human CD34+ cells mature in the thymus. Blood, 115(2):261-265.

Song, J; Willinger, T; Rongvaux, A; Eynon, E E; Stevens, S; Manz, M G; Flavell, R A; Galán, J E (2010). A mouse model for the human pathogen Salmonella typhi. Cell Host & Microbe, 8(4):369-376.

Onai, N; Manz, M G; Schmid, M A (2010). Isolation of common dendritic cell progenitors (CDP) from mouse bone marrow. In: Naik, S H. Dendritic Cell Protocols. United States: Springer / Humana Press, 195-203.

Manz, M G; Di Santo, J P (2009). Renaissance for mouse models of human hematopoiesis and immunobiology. Nature Immunology, (10):1039-1042.

Legrand, N; Ploss, A; Balling, R; Becker, P D; Borsotti, C; Brezillon, N; Debarry, J; De Jong, Y; Deng, H; Di Santo, J P; Eisenbarth, S; Eynon, E; Flavell, R A; Guzman, C A; Huntington, N D; Kremsdorf, D; Manns, M P; Manz, M G; Mention, J J; Ott, M; Rathinam, C; Rice, C M; Rongvaux, A; Stevens, S; Spits, H; Strick-Marchand, H; Takizawa, H; van Lent, A U; Wang, C; Weijer, K; Willinger, T; Ziegler, P (2009). Humanized mice for modeling human infectious disease: challenges, progress, and outlook. Cell Host & Microbe, 6(1):5-9.

Kingston, D; Schmid, M A; Onai, N; Obata-Onai, A; Baumjohann, D; Manz, M G (2009). The concerted action of GM-CSF and Flt3-ligand on in vivo dendritic cell homeostasis. Blood, 114(4):835-843.

Manz, M G (2009). Flt3L, DCs, and NTregs: team contra GVHD? Blood, 113(25):6267-6268.

Merad, M; Manz, M G (2009). Dendritic cell homeostasis. Blood, 113(15):3418-3427.

Neagu, M R; Ziegler, P; Pertel, T; Strambio-De-Castillia, C; Grütter, C; Martinetti, G; Mazzucchelli, L; Grütter, M; Manz, M G; Luban, J (2009). Potent inhibition of HIV-1 by TRIM5-cyclophilin fusion proteins engineered from human components. Journal of Clinical Investigation, 119(10):3035-3047.

Baenziger, S; Ziegler, P; Mazzucchelli, L; Bronz, L; Speck, R F; Manz, M G (2008). Human T cell development and HIV infection in human hemato-lymphoid system mice. Current Topics in Microbiology and Immunology, 324:125-131.

Baenziger, S; Tussiwand, R; Schlaepfer, E; Mazzucchelli, L; Heikenwalder, M; Kurrer, M O; Behnke, S; Frey, J; Oxenius, A; Joller, H; Aguzzi, A; Manz, M G; Speck, R F (2006). Disseminated and sustained HIV infection in CD34+ cord blood cell-transplanted Rag2-/-gamma c-/- mice. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 103(43):15951-15956.

This list was generated on Fri Jul 28 14:50:24 2017 CEST.