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Derungs, R; Camici, G G; Spescha, R D; Welt, T; Tackenberg, C; Späni, C; Wirth, F; Grimm, A; Eckert, A; Nitsch, R M; Kulic, L (2017). Genetic ablation of the p66(Shc) adaptor protein reverses cognitive deficits and improves mitochondrial function in an APP transgenic mouse model of Alzheimer's disease. Molecular Psychiatry, 22(4):605-614.

van Bergen, J M G; Li, X; Hua, J; Schreiner, S J; Steininger, S C; Quevenco, F C; Wyss, M; Gietl, A F; Treyer, V; Leh, S E; Buck, F; Nitsch, R M; Pruessmann, K P; van Zijl, P C M; Hock, C; Unschuld, P G (2016). Colocalization of cerebral iron with amyloid beta in mild cognitive impairment. Scientific Reports, 6:35514.

Ferretti, M T; Merlini, M; Späni, C; Gericke, C; Schweizer, N; Enzmann, G; Engelhardt, B; Kulic, L; Suter, T; Nitsch, R M (2016). T-cell brain infiltration and immature antigen-presenting cells in transgenic models of Alzheimer's disease-like cerebral amyloidosis. Brain, Behavior, and Immunity, 54:211-225.

Spescha, R D; Klohs, J; Semerano, A; Giacalone, G; Derungs, R S; Reiner, M F; Rodriguez Gutierrez, D; Mendez-Carmona, N; Glanzmann, M; Savarese, G; Kränkel, N; Akhmedov, A; Keller, S; Mocharla, P; Kaufmann, M R; Wenger, R H; Vogel, J; Kulic, L; Nitsch, R M; Beer, J H; Peruzzotti-Jametti, L; Sessa, Maria; Lüscher, Thomas F; Camici, G G (2015). Post-ischaemic silencing of p66Shc reduces ischaemia/reperfusion brain injury and its expression correlates to clinical outcome in stroke. European Heart Journal, 36(25):1590-1600.

Birnbaum, J H; Bali, J; Rajendran, L; Nitsch, R M; Tackenberg, C (2015). Calcium flux-independent NMDA receptor activity is required for Aβ oligomer-induced synaptic loss. Cell Death and Disease, 6:e1791.

Santuccione, A C; Merlini, M; Shetty, A; Tackenberg, C; Bali, J; Ferretti, M T; McAfoose, J; Kulic, L; Bernreuther, C; Welt, T; Grimm, J; Glatzel, M; Rajendran, L; Hock, C; Nitsch, R M (2013). Active vaccination with ankyrin G reduces β-amyloid pathology in APP transgenic mice. Molecular Psychiatry, 18(3):358-368.

Bengtsson, S K; Johansson, M; Bäckström, T; Nitsch, R M; Wang, M (2013). Brief but chronic increase in allopregnanolone cause accelerated AD pathology eifferently in two mouse models. Current Alzheimer research, 10(1):38-47.

Spescha, R D; Shi, Y; Wegener, S; Keller, S; Weber, B; Wyss, M M; Lauinger, N; Tabatabai, G; Paneni, F; Cosentino, F; Hock, C; Weller, M; Nitsch, R M; Lüscher, T F; Camici, G G (2013). Deletion of the ageing gene p66Shc reduces early stroke size following ischaemia/reperfusion brain injury. European Heart Journal, 34(2):96-103.

Tackenberg, C; Grinschgl, S; Trutzel, A; Santuccione, A C; Frey, M C; Konietzko, U; Grimm, J; Brandt, R; Nitsch, R M (2013). NMDA receptor subunit composition determines beta-amyloid-induced neurodegeneration and synaptic loss. Cell Death and Disease, 4:e608.

Kulic, L; McAfoose, J; Welt, T; Tackenberg, C; Späni, C; Wirth, F; Finder, V; Konietzko, U; Giese, M; Eckert, A; Noriaki, K; Shimizu, T; Murakami, K; Irie, K; Rasool, S; Glabe, C; Hock, C; Nitsch, R M (2012). Early accumulation of intracellular fibrillar oligomers and late congophilic amyloid angiopathy in mice expressing the Osaka intra-Aβ APP mutation. Translational Psychiatry, 2:e183.

Hermann, D M; Keyvani, K; van de Nes, J; Weimar, C; Wiltfang, J; Nitsch, R M; Szodorai, A (2011). Brain-reactive β-amyloid antibodies in primary CNS angiitis with cerebral amyloid angiopathy. Neurology, 77(5):503-505.

Cattepoel, S; Hanenberg, M; Kulic, L; Nitsch, R M (2011). Chronic intranasal treatment with an anti-Aβ(30-42) scFv antibody ameliorates amyloid pathology in a transgenic mouse model of Alzheimer's disease. PLoS ONE, 6(4):e18296.

Kulic, L; Wollmer, M A; Rhein, V; Pagani, L; Kuehnle, K; Cattepoel, S; Tracy, J; Eckert, A; Nitsch, R M (2011). Combined expression of tau and the Harlequin mouse mutation leads to increased mitochondrial dysfunction, tau pathology and neurodegeneration. Neurobiology of Aging, 32(10):1827-1838.

Klohs, J; Deistung, A; Schweser, F; Grandjean, J; Dominietto, M; Waschkies, C; Nitsch, R M; Knuesel, I; Reichenbach, J R; Rudin, M (2011). Detection of cerebral microbleeds with quantitative susceptibility mapping in the ArcAbeta mouse model of cerebral amyloidosis. Journal of Cerebral Blood Flow and Metabolism, 31(12):2282-2292.

Attems, J; Ittner, A; Jellinger, K; Nitsch, R M; Maj, M; Wagner, L; Götz, J; Heikenwalder, M (2011). Reduced secretagogin expression in the hippocampus of P301L tau transgenic mice. Journal of Neural Transmission, 118(5):737-745.

Ovchinnikova, O Y; Finder, V H; Vodopivec, I; Nitsch, R M; Glockshuber, R (2011). The Osaka FAD mutation E22Δ leads to the formation of a previously unknown type of amyloid β fibrils and modulates Aβ neurotoxicity. Journal of Molecular Biology, 408(4):780-791.

Merlini, M; Meyer, E P; Ulmann-Schuler, A; Nitsch, R M (2011). Vascular β-amyloid and early astrocyte alterations impair cerebrovascular function and cerebral metabolism in transgenic arcAβ mice. Acta Neuropathologica, 122(3):293-311.

Kocherhans, S; Madhusudan, A; Doehner, J; Breu, K S; Nitsch, R M; Fritschy, J M; Knuesel, I (2010). Reduced Reelin expression accelerates amyloid-beta plaque formation and tau pathology in transgenic Alzheimer's disease mice. Journal of Neuroscience, 30(27):9228-9240.

Finder, V H; Vodopivec, I; Nitsch, R M; Glockshuber, R (2010). The Recombinant Amyloid-beta Peptide Abeta1-42 Aggregates Faster and Is More Neurotoxic than Synthetic Abeta1-42. Journal of Molecular Biology, 396(1):9-18.

Serrano-Pozo, A; William, C M; Ferrer, I; Uro-Coste, E; Delisle, M B; Maurage, C A; Hock, C; Nitsch, R M; Masliah, E; Growdon, J H; Frosch, M P; Hyman, B T (2010). Beneficial effect of human anti-amyloid-beta active immunization on neurite morphology and tau pathology. Brain: A Journal of Neurology, 133(5):1312-1327.

Konietzko, U; Goodger, Z V; Meyer, Michelle; Kohli, B M; Lahiri, D K; Bosset, J; Nitsch, R M (2010). Co-localization of the amyloid precursor protein and Notch intracellular domains in nuclear transcription factories. Neurobiology of Aging, 31(1):58-73.

Princz-Kranz, F L; Mueggler, T; Knobloch, M; Nitsch, R M; Rudin, M (2010). Vascular response to acetazolamide decreases as a function of age in the arcA beta mouse model of cerebral amyloidosis. Neurobiology of Disease, 40(1):284-292.

Biscaro, B; Lindvall, O; Hock, C; Ekdahl, C T; Nitsch, R M (2009). Abeta immunotherapy protects morphology and survival of adult-born neurons in doubly transgenic APP/PS1 mice. Journal of Neuroscience, 29(45):14108-14119.

Kuehnle, K; Ledesma, M D; Kalvodova, L; Smith, A E; Crameri, A; Skaanes-Brunner, F; Thelen, K M; Kulic, L; Lütjohann, D; Heppner, F L; Nitsch, R M; Mohajeri, M H (2009). Age-dependent increase in desmosterol restores DRM formation and membrane-related functions in cholesterol-free DHCR24(-/-) mice. Neurochemical Research (34, 1167-82). Neurochemical Research, 34(8):1522.

Goodger, Z V; Rajendran, L; Trutzel, A; Kohli, B M; Nitsch, R M; Konietzko, U (2009). Nuclear signaling by the APP intracellular domain occurs predominantly through the amyloidogenic processing pathway. Journal of Cell Science, 122(Pt 20):3703-3714.

Vodopivec, I; Galichet, A; Knobloch, M; Bierhaus, A; Heizmann, C W; Nitsch, R M (2009). RAGE Does Not Affect Amyloid Pathology in Transgenic ArcAbeta Mice. Neurodegenerative Diseases, 6(5-6):270-280.

Kuehnle, K; Crameri, A; Kälin, R E; Luciani, P; Benvenuti, S; Peri, A; Ratti, F; Rodolfo, M; Kulic, L; Heppner, F L; Nitsch, R M; Mohajeri, M H (2008). Prosurvival effect of DHCR24/Seladin-1 in acute and chronic responses to oxidative stress. Molecular and Cellular Biology, 28(2):539-550.

Berson, A; Knobloch, M; Hanan, M; Diamant, S; Sharoni, M; Schuppli, D; Geyer, B C; Ravid, R; Mor, T S; Nitsch, R M; Soreq, H (2008). Changes in readthrough acetylcholinesterase expression modulate amyloid-beta pathology. Brain: A Journal of Neurology, 131(1):109-119.

Buchmann, A; Montadori, C R A; Hänggi, Jürgen; Aerni, A; Vrticka, P; Luechinger, Roger; Boesiger, Peter; Hock, Christoph; Nitsch, R M; de Quervain, D J F; Papassotiropoulos, A; Henke, K (2008). Prion protein M129V polymorphism affects retrieval-related brain activity. Neuropsychologia, 46(9):2389-2402.

Nitsch, R M; Hock, C (2008). Targeting beta-amyloid pathology in Alzheimer's disease with Abeta immunotherapy. Neurotherapeutics, 5(3):415-420.

Knobloch, M; Farinelli, M; Konietzko, U; Nitsch, R M; Mansuy, I M (2007). Abeta oligomer-mediated long-term potentiation impairment involves protein phosphatase 1-dependent mechanisms. Journal of Neuroscience, 27(29):7648-7653.

Wollmer, M A; Sleegers, K; Ingelsson, M; Zekanowski, C; Brouwers, N; Maruszak, A; Brunner, F; Huynh, K D; Kilander, L; Brundin, R M; Hedlund, M; Giedraitis, V; Glaser, A; Engelborghs, S; De Deyn, P P; Kapaki, E; Tsolaki, M; Daniilidou, M; Molyva, D; Paraskevas, G P; Thal, D R; Barcikowska, M; Kuznicki, J; Lannfelt, L; Van Broeckhoven, C; Nitsch, R M; Hock, C; Papassotiropoulos, A (2007). Association study of cholesterol-related genes in Alzheimer's disease. Neurogenetics, 8(3):179-188.

Mondadori, C R A; de Quervain, D J F; Buchmann, A; Mustovic, H; Wollmer, M A; Schmidt, C F; Boesiger, P; Hock, C; Nitsch, R M; Papassotiropoulos, A; Henke, K (2007). Better memory and neural efficiency in young apolipoprotein E epsilon4 carriers. Cerebral Cortex, 17(8):1934-1947.

De Ferrari, G V; Papassotiropoulos, A; Biechele, T; Wavrant-De Vrieze, F; Avila, M E; Major, M B; Myers, A; Sáez, K; Henríquez, J P; Zhao, A; Wollmer, M A; Nitsch, R M; Hock, C; Morris, C M; Hardy, J; Moon, R T (2007). Common genetic variation within the low-density lipoprotein receptor-related protein 6 and late-onset Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 104(22):9434-3439.

Knobloch, M; Konietzko, U; Krebs, D C; Nitsch, R M (2007). Intracellular Abeta and cognitive deficits precede beta-amyloid deposition in transgenic arcAbeta mice. Neurobiology of Aging, 28(9):1297-1306.

Kulic, L; Kurosinski, P; Chen, F; Tracy, J; Mohajeri, M H; Li, H; Nitsch, R M; Götz, J (2006). Active immunization trial in Abeta42-injected P301L tau transgenic mice. Neurobiology of Disease, 22(1):50-56.

Mondadori, C R A; Buchmann, A; Mustovic, H; Schmidt, C F; Boesiger, P; Nitsch, R M; Hock, C; Streffer, J; Henke, K (2006). Enhanced brain activity may precede the diagnosis of Alzheimer's disease by 30 years. Brain: A Journal of Neurology, 129(Pt 11):2908-2922.

Wollmer, M A; Kapaki, E; Hersberger, M; Muntwyler, J; Brunner, F; Tsolaki, M; Akatsu, H; Kosaka, K; Michikawa, M; Molyva, D; Paraskevas, G P; Lütjohann, D; von Eckardstein, A; Hock, C; Nitsch, R M; Papassotiropoulos, A (2006). Ethnicity-dependent genetic association of ABCA2 with sporadic Alzheimer's disease. American Journal of Medical Genetics. Part B, 141B(5):534-536.

Avila, J; Nitsch, R M; Haass, C; De Strooper, B (2006). European Alzheimer disease funding. Nature Medicine, 12(7):776-777.

Wollmer, M A; Nitsch, R M; Hock, C; Papassotiropoulos, A (2006). Genetic association study on colony-stimulating factor 1 in Alzheimer's disease. Neurodegenerative Diseases, 3(6):334-337.

Pennanen, L; Wolfer, D P; Nitsch, R M; Götz, J (2006). Impaired spatial reference memory and increased exploratory behavior in P301L tau transgenic mice. Genes, Brain and Behavior, 5(5):369-379.

Madani, R; Poirier, R; Wolfer, D P; Welzl, H; Groscurth, P; Lipp, H P; Lu, B; El Mouedden, M; Mercken, M; Nitsch, R M; Mohajeri, M H (2006). Lack of neprilysin suffices to generate murine amyloid-like deposits in the brain and behavioral deficit in vivo. Journal of Neuroscience Research, 84(8):1871-1878.

Poirier, R; Wolfer, D P; Welzl, H; Tracy, J; Galsworthy, M J; Nitsch, R M; Mohajeri, M H (2006). Neuronal neprilysin overexpression is associated with attenuation of abeta-related spatial memory deficit. Neurobiology of Disease, 24(3):475-483.

Crameri, A; Biondi, E; Kuehnle, K; Lütjohann, D; Thelen, K M; Perga, S; Dotti, C G; Nitsch, R M; Ledesma, M D; Mohajeri, M H (2006). The role of seladin-1/DHCR24 in cholesterol biosynthesis, APP processing and Abeta generation in vivo. The EMBO Journal, 25(2):432-443.

Papassotiropoulos, A; Wollmer, M A; Aguzzi, A; Hock, Christoph; Nitsch, R M; de Quervain, D J F (2005). The prion gene is associated with human long-term memory. Human Molecular Genetics, 14(15):2241-2246.

Glatzel, M; Mohajeri, M H; Poirier, R; Nitsch, R M; Schwarz, Petra; Lu, B; Aguzzi, A (2005). No influence of amyloid-beta-degrading neprilysin activity on prion pathogenesis. Journal of General Virology, 8(6):1861-1867.

Papassotiropoulos, A; Wollmer, M A; Tsolaki, M; Brunner, F; Molyva, D; Lütjohann, D; Nitsch, R M; Hock, C (2005). A cluster of cholesterol-related genes confers susceptibility for Alzheimer's disease. Journal of Clinical Psychiatry, 66(7):940-947.

Papassotiropoulos, A; Henke, K; Aerni, A; Coluccia, D; Garcia, E; Wollmer, M A; Huynh, K D; Monsch, A U; Stähelin, H B; Hock, C; Nitsch, R M; de Quervain, D J F (2005). Age-dependent effects of the 5-hydroxytryptamine-2a-receptor polymorphism (His452Tyr) on human memory. NeuroReport, 16(8):839-842.

Kohli, B M; Eng, J K; Nitsch, R M; Konietzko, U (2005). An alternative sampling algorithm for use in liquid chromatography/tandem mass spectrometry experiments. Rapid Communications in Mass Spectrometry, 19(5):589-596.

Papassotiropoulos, A; Lambert, J C; Wavrant-De Vrièze, F; Wollmer, M A; von der Kammer, H; Streffer, J R; Maddalena, A; Huynh, K D; Wolleb, S; Lütjohann, D; Schneider, B; Thal, D R; Grimaldi, L M E; Tsolaki, M; Kapaki, E; Ravid, R; Konietzko, U; Hegi, T; Pasch, T; Jung, H; Braak, H; Amouyel, P; Rogaev, E I; Hardy, J; Hock, C; Nitsch, R M (2005). Cholesterol 25-hydroxylase on chromosome 10q is a susceptibility gene for sporadic Alzheimer's disease. Neurodegenerative Diseases, 2(5):233-241.

Hock, C; Nitsch, R M (2005). Clinical observations with AN-1792 using TAPIR analyses. Neurodegenerative Diseases, 2(5):273-276.

Bosshardt, S; Schmidt, C F; Jaermann, T; Degonda, N; Boesiger, P; Nitsch, R M; Hock, C; Henke, K (2005). Effects of memory consolidation on human hippocampal activity during retrieval. Cortex, 41(4):486-498.

Degonda, N; Mondadori, C R A; Bosshardt, S; Schmidt, C F; Boesiger, P; Nitsch, R M; Hock, C; Henke, K (2005). Implicit associative learning engages the hippocampus and interacts with explicit associative learning. Neuron, 46(3):505-520.

Gaugler, M N M; Tracy, J; Kuhnle, K; Crameri, A; Nitsch, R M; Mohajeri, M H (2005). Modulation of Alzheimer's pathology by cerebro-ventricular grafting of hybridoma cells expressing antibodies against Abeta in vivo. FEBS Letters, 579(3):753-756.

Papassotiropoulos, A; Tsolaki, M; Wollmer, M A; Molyva, D; Thal, D R; Huynh, K D; Tracy, J; Staehelin, H B; Monsch, A U; Nitsch, R M; Hock, C (2005). No association of a non-synonymous PLAU polymorphism with Alzheimer's disease and disease-related traits. American Journal of Medical Genetics. Part B, 132B(1):21-23.

Bosshardt, S; Degonda, N; Schmidt, C F; Boesiger, P; Nitsch, R M; Hock, C; Henke, K (2005). One month of human memory consolidation enhances retrieval-related hippocampal activity. Hippocampus, 15(8):1026-1040.

Hock, C; Nitsch, R M (2005). Stand der Forschung zu innovativen Therapieverfahren der Alzheimer-Demenz. In: Berger, M; Normann, C. Highlights der Psychiatrie und Psychotherapie 2005⁄06. München: Urban & Fischer, 3-10.

von Rotz, R C; Kins, S; Hipfel, R; von der Kammer, H; Nitsch, R M (2005). The novel cytosolic RING finger protein dactylidin is up-regulated in brains of patients with Alzheimer's disease. European Journal of Neuroscience, 21(5):1289-1298.

Pennanen, L; Welzl, H; D'Adamo, P; Nitsch, R M; Götz, J (2004). Accelerated extinction of conditioned taste aversion in P301L tau transgenic mice. Neurobiology of Disease, 15(3):500-509.

Koller, M F; Mohajeri, M H; Huber, M; Wollmer, M A; Roth Z'graggen, B V; Sandmeier, E; Moritz, E; Tracy, J; Nitsch, R M; Christen, P (2004). Active immunization of mice with an Abeta-Hsp70 vaccine. Neurodegenerative Diseases, 1(1):20-28.

Greeve, I; Kretzschmar, D; Tschäpe, J A; Beyn, A; Brellinger, C; Schweizer, M; Nitsch, R M; Reifegerste, R (2004). Age-dependent neurodegeneration and Alzheimer-amyloid plaque formation in transgenic Drosophila. Journal of Neuroscience, 24(16):3899-3906.

Mohajeri, M H; Kuehnle, K; Li, H; Poirier, R; Tracy, J; Nitsch, R M (2004). Anti-amyloid activity of neprilysin in plaque-bearing mouse models of Alzheimer's disease. FEBS Letters, 562(1-3):16-21.

Schiltz, J G; Salzer, U; Mohajeri, M H; Franke, D; Heinrich, J; Pavlovic, J; Wollmer, M A; Nitsch, R M; Moelling, K (2004). Antibodies from a DNA peptide vaccination decrease the brain amyloid burden in a mouse model of Alzheimer's disease. Journal of Molecular Medicine, 82(10):706-714.

Mohajeri, M H; Gaugler, M N M; Martinez, J; Tracy, J; Li, H; Crameri, A; Kuehnle, K; Wollmer, M A; Nitsch, R M (2004). Assessment of the bioactivity of antibodies against beta-amyloid peptide in vitro and in vivo. Neurodegenerative Diseases, 1(4-5):160-167.

Repetto, E; Russo, C; Venezia, V; Nizzari, M; Nitsch, R M; Schettini, G (2004). BACE1 overexpression regulates amyloid precursor protein cleavage and interaction with the ShcA adapter. Annals of the New York Academy of Sciences, 1030:330-338.

Papassotiropoulos, A; Maddalena, A; Gretener, D; Nitsch, R M; Hock, C (2004). Cerebrospinal fluid biomarkers for the diagnosis of Alzheimer's disease. In: Hyman, B T; Demonet, L F; Christen, Y. The Living Brain and Alzheimer’s Disease. Berlin [etc.]: Springer Verlag, 17-24.

Maddalena, A S; Papassotiropoulos, A; Gonzalez-Agosti, C; Signorell, A; Hegi, T; Pasch, T; Nitsch, R M; Hock, C (2004). Cerebrospinal fluid profile of amyloid beta peptides in patients with Alzheimer's disease determined by protein biochip technology. Neurodegenerative Diseases, 1(4-5):231-235.

Finckh, U; Hock, C; Nitsch, R M (2004). Die Alzheimer-Krankheit: Molekulare Grundlagen und Therapieansätzte. In: Ganten, D; Ruckpaul, K; Ruiz-Torres, A. Molekularmedizinische Grundlagen von altersspezifischen Erkrankungen. Heidelberg: Springer Verlag, 148-179.

de Quervain, D J F; Poirier, R; Wollmer, M A; Grimaldi, L M E; Tsolaki, M; Streffer, J R; Hock, C; Nitsch, R M; Mohajeri, M H; Papassotiropoulos, A (2004). Glucocorticoid-related genetic susceptibility for Alzheimer's disease. Human Molecular Genetics, 13(1):47-52.

Nitsch, R M (2004). Immunotherapy of Alzheimer disease. Alzheimer Disease and Associated Disorders, 18(4):185-189.

Wolfer, D P; Litvin, O; Morf, S; Nitsch, R M; Lipp, H P; Würbel, H (2004). Laboratory animal welfare: cage enrichment and mouse behaviour. Nature, 432(7019):821-822.

Grasbon-Frodl, E; Lorenz, H; Mann, U; Nitsch, R M; Windl, O; Kretzschmar, H A (2004). Loss of glycosylation associated with the T183A mutation in human prion disease. Acta Neuropathologica, 108(6):476-484.

Aerni, A; Traber, R; Hock, C; Roozendaal, B; Schelling, G; Papassotiropoulos, A; Nitsch, R M; Schnyder, U; de Quervain, D J F (2004). Low-dose cortisol for symptoms of posttraumatic stress disorder. American Journal of Psychiatry, 161(8):1488-1490.

Günther, C; von Hadeln, K; Müller-Thomsen, T; Alberici, A; Binetti, G; Hock, C; Nitsch, R M; Stoppe, G; Reiss, J; Gal, A; Finckh, U (2004). Possible association of mitochondrial transcription factor A (TFAM) genotype with sporadic Alzheimer disease. Neuroscience Letters, 369(3):219-223.

von Rotz, R C; Kohli, B M; Bosset, J; Meier, M; Suzuki, T; Nitsch, R M; Konietzko, U (2004). The APP intracellular domain forms nuclear multiprotein complexes and regulates the transcription of its own precursor. Journal of Cell Science, 117(Pt 19):4435-4448.

Mohajeri, M H; Madani, R; Saini, K; Lipp, H P; Nitsch, R M; Wolfer, D P (2004). The impact of genetic background on neurodegeneration and behavior in seizured mice. Genes, Brain and Behavior, 3(4):228-239.

Mohajeri, M H; Saini, K D; Nitsch, R M (2004). Transgenic BACE expression in mouse neurons accelerates amyloid plaque pathology. Journal of Neural Transmission, 111(3):413-425.

de Quervain, D J F; Henke, K; Aerni, A; Coluccia, D; Wollmer, M A; Hock, C; Nitsch, R M; Papassotiropoulos, A (2003). A functional genetic variation of the 5-HT2a receptor affects human memory. Nature Neuroscience, 6(11):1141-1142.

Wollmer, M A; Streffer, J R; Lütjohann, D; Tsolaki, M; Iakovidou, V; Hegi, T; Pasch, T; Jung, H H; von Bergmann, K; Nitsch, R M; Hock, C; Papassotiropoulos, A (2003). ABCA1 modulates CSF cholesterol levels and influences the age at onset of Alzheimer's disease. Neurobiology of Aging, 24(3):421-426.

Kins, S; Kurosinski, P; Nitsch, R M; Götz, J (2003). Activation of the ERK and JNK signaling pathways caused by neuron-specific inhibition of PP2A in transgenic mice. American Journal of Pathology, 163(3):833-843.

Henke, K; Treyer, V; Nagy, E T; Kneifel, S; Dürsteler, M; Nitsch, R M; Buck, A (2003). Active hippocampus during nonconscious memories. Consciousness and Cognition, 12(1):31-48.

Benussi, L; Ghidoni, R; Steinhoff, T; Alberici, A; Villa, A; Mazzoli, F; Nicosia, F; Barbiero, L; Broglio, L; Feudatari, E; Signorini, S; Finckh, U; Nitsch, R M; Binetti, G (2003). Alzheimer disease-associated cystatin C variant undergoes impaired secretion. Neurobiology of Disease, 13(1):15-21.

Chen, F; Ferrari, A; Schild, A; Kurosinski, P; David, D; Hoerndli, F; Pennanen, L; Kins, S; van Dorpe, J; Nitsch, R M; Götz, J (2003). Amyloid-induced neurofibrillary tangle formation. In: Iqbal, K; Winblad, B. Alzheimer’s disease and related disorders: Research advances. Ana Aslan International Foundation, 343-354.

Hock, C; Konietzko, U; Streffer, J R; Tracy, J; Signorell, A; Müller-Tillmanns, B; Lemke, U; Henke, K; Moritz, E; Garcia, E; Wollmer, M A; Umbricht, D; de Quervain, D J F; Hofmann, M; Maddalena, A; Papassotiropoulos, A; Nitsch, R M (2003). Antibodies against beta-amyloid slow cognitive decline in Alzheimer's disease. Neuron, 38(4):547-554.

Finckh, U; van Hadeln, K; Müller-Thomsen, T; Alberici, A; Binetti, G; Hock, C; Nitsch, R M; Stoppe, G; Reiss, J; Gal, A (2003). Association of late-onset Alzheimer disease with a genotype of PLAU, the gene encoding urokinase-type plasminogen activator on chromosome 10q22.2. Neurogenetics, 4(4):213-217.

Ferrari, A; Hoerndli, F; Baechi, T; Nitsch, R M; Götz, J (2003). Beta-Amyloid induces paired helical filament-like tau filaments in tissue culture. Journal of Biological Chemistry, 278(41):40162-40168.

Maddalena, A; Papassotiropoulos, A; Müller-Tillmanns, B; Jung, H H; Hegi, T; Nitsch, R M; Hock, C (2003). Biochemical diagnosis of Alzheimer disease by measuring the cerebrospinal fluid ratio of phosphorylated tau protein to beta-amyloid peptide42. Archives of Neurology, 60(9):1202-1206.

Henke, K; Treyer, V; Weber, B; Nitsch, R M; Hock, C; Wieser, H G; Buck, A (2003). Functional neuroimaging predicts individual memory outcome after amygdalohippocampectomy. NeuroReport, 14(9):1197-1202.

Wollmer, M A; Streffer, J R; Tsolaki, M; Grimaldi, L M E; Lütjohann, D; Thal, D; von Bergmann, K; Nitsch, R M; Hock, C; Papassotiropoulos, A (2003). Genetic association of acyl-coenzyme A: cholesterol acyltransferase with cerebrospinal fluid cholesterol levels, brain amyloid load, and risk for Alzheimer's disease. Molecular Psychiatry, 8(6):635-638.

Papassotiropoulos, A; Hock, C; Nitsch, R M (2003). Genetik gerontopsychiatrischer Erkrankungen. In: Förstl, H. Lehrbuch der Gerontopsychiatrie und –psychotherapie: Grundlagen, Klinik, Therapie. Stuttgart: Thieme, 27-36.

de Quervain, D J F; Henke, K; Aerni, A; Treyer, V; McGaugh, J L; Berthold, T; Nitsch, R M; Buck, A; Roozendaal, B; Hock, C (2003). Glucocorticoid-induced impairment of declarative memory retrieval is associated with reduced blood flow in the medial temporal lobe. European Journal of Neuroscience, 17(6):1296-1302.

Papassotiropoulos, A; Streffer, J R; Tsolaki, M; Schmid, S; Thal, D; Nicosia, F; Iakovidou, V; Maddalena, A; Lütjohann, D; Ghebremedhin, E; Hegi, T; Pasch, T; Träxler, M; Brühl, A; Benussi, L; Binetti, G; Braak, H; Nitsch, R M; Hock, C (2003). Increased brain beta-amyloid load, phosphorylated tau, and risk of Alzheimer disease associated with an intronic CYP46 polymorphism. Archives of Neurology, 60(1):29-35.

Mohajeri, M H; Saini, K; Li, H; Crameri, A; Lipp, H P; Wolfer, D P; Nitsch, R M (2003). Intact spatial memory in mice with seizure-induced partial loss of hippocampal pyramidal neurons. Neurobiology of Disease, 12(3):174-181.

Henke, K; Mondadori, C R A; Treyer, V; Nitsch, R M; Buck, A; Hock, C (2003). Nonconscious formation and reactivation of semantic associations by way of the medial temporal lobe. Neuropsychologia, 41(8):863-876.

Streffer, J R; Papassotiropoulos, A; Kurosinski, P; Signorell, A; Wollmer, M A; Tsolaki, M; Iakovidou, V; Hörndli, F; Bosset, J; Götz, J; Nitsch, R M; Hock, C (2003). Saitohin gene is not associated with Alzheimer's disease. Journal of Neurology, Neurosurgery, and Psychiatry, 74(3):362-363.

Hock, C; Maddalena, A; Raschig, A; Müller-Spahn, F; Eschweiler, G; Hager, K; Heuser, I; Hampel, H; Müller-Thomsen, T; Oertel, W; Wienrich, M; Signorell, A; Gonzalez-Agosti, C; Nitsch, R M (2003). Treatment with the selective muscarinic m1 agonist talsaclidine decreases cerebrospinal fluid levels of A beta 42 in patients with Alzheimer's disease. Amyloid, 10(1):1-6.

Hock, C; Konietzko, U; Papassotiropoulos, A; Wollmer, A; Streffer, J; von Rotz, R C; Davey, G; Moritz, E; Nitsch, R M (2002). Generation of antibodies specific for beta-amyloid by vaccination of patients with Alzheimer disease. Nature Medicine, 8(11):1270-1275.

Wollmer, M A; Papassotiropoulos, A; Streffer, J R; Grimaldi, L M E; Kapaki, E; Salani, G; Paraskevas, G P; Maddalena, A; de Quervain, D; Bieber, C; Umbricht, D; Lemke, U; Bosshardt, S; Degonda, N; Henke, K; Hegi, T; Jung, H H; Pasch, T; Hock, C; Nitsch, R M (2002). Genetic polymorphisms and cerebrospinal fluid levels of tissue inhibitor of metalloproteinases 1 in sporadic Alzheimer's disease. Psychiatric Genetics, 12(3):155-160.

Finckh, U; Müller-Thomsen, T; Mann, U; Eggers, C; Marksteiner, J; Meins, W; Binetti, G; Alberici, A; Sonderegger, P; Hock, C; Nitsch, R M; Gal, A (2000). High frequency of mutations in four different disease genes in early-onset dementia. Annals of the New York Academy of Sciences, 920:100-106.

This list was generated on Sat Dec 16 11:08:54 2017 CET.