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Number of items: 46.

Bergmann, Christina; Brandt, Amelie; Merlevede, Benita; Hallenberger, Ludwig; Dees, Clara; Wohlfahrt, Thomas; Pötter, Sebastian; Zhang, Yun; Chen, Chih-Wei; Mallano, Tatiana; Liang, Ruifang; Kagwiria, Rosebeth; Kreuter, Alexander; Pantelaki, Ioanna; Bozec, Aline; Abraham, David; Rieker, Ralf; Ramming, Andreas; Distler, Oliver; Schett, Georg; Distler, Jörg H W (2017). The histone demethylase Jumonji domain-containing protein 3 (JMJD3) regulates fibroblast activation in systemic sclerosis. Annals of the Rheumatic Diseases:Epub ahead of print.

Chakraborty, Debomita; Šumová, Barbora; Mallano, Tatjana; Chen, Chih-Wei; Distler, Alfiya; Bergmann, Christina; Ludolph, Ingo; Horch, Raymund E; Gelse, Kolja; Ramming, Andreas; Distler, Oliver; Schett, Georg; Šenolt, Ladislav; Distler, Jörg H W (2017). Activation of STAT3 integrates common profibrotic pathways to promote fibroblast activation and tissue fibrosis. Nature Communications, 8(1):1130.

Schmitt, Verena; Hahn, Madelaine; Kästele, Verena; Wagner, Olga; Wiendl, Maximilian; Derer, Anja; Taddeo, Adriano; Hahne, Stefanie; Radbruch, Andreas; Jäck, Hans-Martin; Schuh, Wolfgang; Mielenz, Dirk; Gay, Steffen; Schett, Georg; Hueber, Axel J; Frey, Silke (2017). Interleukin-36 receptor mediates the crosstalk between plasma cells and synovial fibroblasts. European Journal of Immunology:Epub ahead of print.

Huang, Jingang; Maier, Christiane; Zhang, Yun; Soare, Alina; Dees, Clara; Beyer, Christian; Harre, Ulrike; Chen, Chih-Wei; Distler, Oliver; Schett, Georg; Wollin, Lutz; Distler, Jörg H W (2017). Nintedanib macrophage activation and ameliorates vascular and fibrotic manifestations in the Fra2 mouse model of systemic sclerosis. Annals of the Rheumatic Diseases, 76(11):1941-1948.

Rauber, Simon; Luber, Markus; Weber, Stefanie; Maul, Lisa; Soare, Alina; Wohlfahrt, Thomas; Lin, Neng-Yu; Dietel, Katharina; Bozec, Aline; Herrmann, Martin; Kaplan, Mark H; Weigmann, Benno; Zaiss, Mario M; Fearon, Ursula; Veale, Douglas J; Cañete, Juan D; Distler, Oliver; Rivellese, Felice; Pitzalis, Costantino; Neurath, Markus F; McKenzie, Andrew N J; Wirtz, Stefan; Schett, Georg; Distler, Jörg H W; Ramming, Andreas (2017). Resolution of inflammation by interleukin-9-producing type 2 innate lymphoid cells. Nature Medicine, 23(8):938-944.

Beyer, Christian; Huscher, Dörte; Ramming, Andreas; Bergmann, Christina; Avouac, Jerome; Guiducci, Serena; Meier, Florian; Vettori, Serena; Siegert, Elise; Jaeger, Veronika K; Maurer, Britta; Riemekasten, Gabriela; Walker, Ulrich; Müller-Ladner, Ulf; Valentini, Gabriele; Matucci-Cerinic, Marco; Allanore, Yannick; Distler, Oliver; Schett, Georg; Distler, Jörg H W (2017). Elevated serum levels of sonic hedgehog are associated with fibrotic and vascular manifestations in systemic sclerosis. Annals of the Rheumatic Diseases:Epub ahead of print.

Zhang, Yun; Liang, Ruifang; Chen, Chih-Wei; Mallano, Tatjana; Dees, Clara; Distler, Alfiya; Reich, Adam; Bergmann, Christina; Ramming, Andreas; Gelse, Kolja; Mielenz, Dirk; Distler, Oliver; Schett, Georg; Distler, Jörg H W (2017). JAK1-dependent transphosphorylation of JAK2 limits the antifibrotic effects of selective JAK2 inhibitors on long-term treatment. Annals of the Rheumatic Diseases, 76(8):1467-1475.

Palumbo-Zerr, Katrin; Soare, Alina; Zerr, Pawel; Liebl, Andrea; Mancuso, Rossella; Tomcik, Michal; Sumova, Barbora; Dees, Clara; Chen, Chih-Wei; Wohlfahrt, Thomas; Mallano, Tatjana; Distler, Alfiya; Ramming, Andreas; Gelse, Kolja; Mihai, Carina; Distler, Oliver; Schett, Georg; Distler, Jörg H W (2017). Composition of TWIST1 dimers regulates fibroblast activation and tissue fibrosis. Annals of the Rheumatic Diseases, 76(1):244-251.

Liang, Ruifang; Šumová, Barbora; Cordazzo, Cinzia; Mallano, Tatjana; Zhang, Yun; Wohlfahrt, Thomas; Dees, Clara; Ramming, Andreas; Krasowska, Dorota; Michalska-Jakubus, Małgorzata; Distler, Oliver; Schett, Georg; Šenolt, Ladislav; Distler, Jörg H W (2016). The transcription factor GLI2 as a downstream mediator of transforming growth factor-β-induced fibroblast activation in SSc. Annals of the Rheumatic Diseases, 76(4):756-764.

Mallano, Tatjana; Palumbo-Zerr, Katrin; Zerr, Pawel; Ramming, Andreas; Zeller, Barbara; Beyer, Christian; Dees, Clara; Huang, Jingang; Hai, Tsonwin; Distler, Oliver; Schett, Georg; Distler, Jörg H W (2016). Activating transcription factor 3 regulates canonical TGFβ signalling in systemic sclerosis. Annals of the Rheumatic Diseases, 75(3):586-592.

Zerr, Pawel; Palumbo-Zerr, Katrin; Huang, Jingang; Tomcik, Michal; Sumova, Barbora; Distler, Oliver; Schett, Georg; Distler, Jörg H W (2016). Sirt1 regulates canonical TGF-β signalling to control fibroblast activation and tissue fibrosis. Annals of the Rheumatic Diseases, 75(1):226-233.

Tomcik, Michal; Palumbo-Zerr, Katrin; Zerr, Pawel; Sumova, Barbora; Avouac, Jerome; Dees, Clara; Distler, Alfiya; Becvar, Radim; Distler, Oliver; Schett, Georg; Senolt, Ladislav; Distler, Jörg H W (2016). Tribbles homologue 3 stimulates canonical TGF-β signalling to regulate fibroblast activation and tissue fibrosis. Annals of the Rheumatic Diseases, 75(3):609-616.

Aigner, Elmar; Stadlmayr, Andreas; Huber-Schönauer, Ursula; Zwerina, Jochen; Husar-Memmer, Emma; Niederseer, David; Eder, Sebastian K; Stickel, Felix; Pirich, Christian; Schett, Georg; Patsch, Wolfgang; Datz, Christian (2015). Parathyroid hormone is related to dysplasia and a higher rate of distal colorectal adenoma in women but not men. Hormones and Cancer, 6(4):153-160.

Dees, Clara; Beyer, Christian; Distler, Alfiya; Soare, Alina; Zhang, Yun; Palumbo-Zerr, Katrin; Distler, Oliver; Schett, Georg; Sandner, Peter; Distler, Jörg H W (2015). Stimulators of soluble guanylate cyclase (sGC) inhibit experimental skin fibrosis of different aetiologies. Annals of the Rheumatic Diseases, 74(8):1621-1625.

Zerr, Pawel; Vollath, Stefan; Palumbo-Zerr, Katrin; Tomcik, Michal; Huang, Jingang; Distler, Alfiya; Beyer, Christian; Dees, Clara; Gela, Kolja; Distler, Oliver; Schett, Georg; Distler, Jörg H W (2015). Vitamin D receptor regulates TGF-β signalling in systemic sclerosis. Annals of the Rheumatic Diseases, 74(3):e20.

Palumbo-Zerr, Katrin; Zerr, Pawel; Distler, Alfiya; Fliehr, Judith; Mancuso, Rossella; Huang, Jingang; Mielenz, Dirk; Tomcik, Michal; Fürnrohr, Barbara G; Scholtysek, Carina; Dees, Clara; Beyer, Christian; Krönke, Gerhard; Metzger, Daniel; Distler, Oliver; Schett, Georg; Distler, Jörg H W (2015). Orphan nuclear receptor NR4A1 regulates transforming growth factor-β signaling and fibrosis. Nature Medicine, 21(2):150-158.

Beyer, Christian; Huang, Jingang; Beer, Jürgen; Zhang, Yun; Palumbo-Zerr, Katrin; Zerr, Pawel; Distler, Alfiya; Dees, Clara; Maier, Christiane; Munoz, Louis; Krönke, Gerhard; Uderhardt, Stefan; Distler, Oliver; Jones, Simon; Rose-John, Stefan; Oravecz, Tamas; Schett, Georg; Distler, Jörg Hw (2015). Activation of liver X receptors inhibits experimental fibrosis by interfering with interleukin-6 release from macrophages. Annals of the Rheumatic Diseases, 74(6):1317-1324.

Venalis, Paulius; Kumánovics, Gábor; Schulze-Koops, Hendrik; Distler, Alfiya; Dees, Clara; Zerr, Pawel; Palumbo-Zerr, Katrin; Czirják, László; Mackevic, Zygmunt; Lundberg, Ingrid E; Distler, Oliver; Schett, Georg; Distler, Jörg H W (2015). Cardiomyopathy in murine models of systemic sclerosis. Arthritis and Rheumatology, 67(2):508-516.

Zhang, Yun; Dees, Clara; Beyer, Christian; Lin, Neng-Yu; Distler, Alfiya; Zerr, Pawel; Palumbo, Katrin; Susok, Laura; Kreuter, Alexander; Distler, Oliver; Schett, Georg; Distler, Jörg H W (2015). Inhibition of casein kinase II reduces TGFβ induced fibroblast activation and ameliorates experimental fibrosis. Annals of the Rheumatic Diseases, 74(5):936-943.

Tomcik, Michal; Palumbo-Zerr, Katrin; Zerr, Pawel; Avouac, Jerome; Dees, Clara; Sumova, Barbora; Distler, Alfiya; Beyer, Christian; Cerezo, Lucie Andres; Becvar, Radim; Distler, Oliver; Grigorian, Mariam; Schett, Georg; Senolt, Ladislav; Distler, Jörg H W (2015). S100A4 amplifies TGF-β-induced fibroblast activation in systemic sclerosis. Annals of the Rheumatic Diseases, 74(9):1748-1755.

Beyer, Christian; Zenzmaier, Christoph; Palumbo-Zerr, Katrin; Mancuso, Rossella; Distler, Alfiya; Dees, Clara; Zerr, Pawel; Huang, Jingang; Maier, Christiane; Pachowsky, Milena L; Friebe, Andreas; Sandner, Peter; Distler, Oliver; Schett, Georg; Berger, Peter; Distler, Jörg H W (2015). Stimulation of the soluble guanylate cyclase (sGC) inhibits fibrosis by blocking non-canonical TGFβ signalling. Annals of the Rheumatic Diseases, 74(7):1408-1416.

Distler, Alfiya; Lang, Veronika; Del Vecchio, Tina; Huang, Jingang; Zhang, Yun; Beyer, Christian; Lin, Neng-Yu; Palumbo-Zerr, Katrin; Distler, Oliver; Schett, Georg; Distler, Jörg H W (2014). Combined inhibition of morphogen pathways demonstrates additive antifibrotic effects and improved tolerability. Annals of the Rheumatic Diseases, 73(6):1264-1268.

Tomcik, Michal; Zerr, Pawel; Pitkowski, Jana; Palumbo-Zerr, Katrin; Avouac, Jérôme; Distler, Oliver; Becvar, Radim; Senolt, Ladislav; Schett, Georg; Distler, Jörg H (2014). Heat shock protein 90 (Hsp90) inhibition targets canonical TGF-β signalling to prevent fibrosis. Annals of the Rheumatic Diseases, 73(6):1215-1222.

Distler, Alfiya; Ziemer, Clara; Beyer, Christian; Lin, Neng-Yu; Chen, Chih-Wei; Palumbo-Zerr, Katrin; Dees, Clara; Weidemann, Alexander; Distler, Oliver; Schett, Georg; Distler, Jörg H W (2014). Inactivation of evenness interrupted (EVI) reduces experimental fibrosis by combined inhibition of canonical and non-canonical Wnt signalling. Annals of the Rheumatic Diseases, 73(3):624-627.

Dees, Clara; Schlottmann, Inga; Funke, Robin; Distler, Alfiya; Palumbo-Zerr, Katrin; Zerr, Pawel; Lin, Neng-Yu; Beyer, Christian; Distler, Oliver; Schett, Georg; Distler, Jörg H W (2014). The Wnt antagonists DKK1 and SFRP1 are downregulated by promoter hypermethylation in systemic sclerosis. Annals of the Rheumatic Diseases, 73(6):1232-1239.

Avouac, Jérôme; Palumbo-Zerr, Katrin; Ruzehaji, Nadira; Tomcik, Michal; Zerr, Pawel; Dees, Clara; Distler, Alfiya; Beyer, Christian; Schneider, Holm; Distler, Oliver; Schett, Georg; Allanore, Yannick; Distler, Jörg H W (2014). The nuclear receptor constitutive androstane receptor/NR1I3 enhances the profibrotic effects of transforming growth factor β and contributes to the development of experimental dermal fibrosis. Arthritis and Rheumatology, 66(11):3140-3150.

Beyer, Christian; Skapenko, Alla; Distler, Alfiya; Dees, Clara; Reichert, Helena; Munoz, Louis; Leipe, Jan; Schulze-Koops, Hendrik; Distler, Oliver; Schett, Georg; Distler, Jörg H W (2013). Activation of pregnane X receptor inhibits experimental dermal fibrosis. Annals of the Rheumatic Diseases, 72(4):621-625.

Lin, Neng-Yu; Beyer, Christian; Gießl, Andreas; Kireva, Trayana; Scholtysek, Carina; Uderhardt, Stefan; Munoz, Luis Enrique; Dees, Clara; Distler, Alfiya; Wirtz, Stefan; Krönke, Gerhard; Spencer, Brian; Distler, Oliver; Schett, Georg; Distler, Jörg H W (2013). Autophagy regulates TNFα-mediated joint destruction in experimental arthritis. Annals of the Rheumatic Diseases, 72(5):761-768.

Beyer, Christian; Reichert, Helena; Akan, Hümeyra; Mallano, Tatjana; Schramm, Amelie; Dees, Clara; Palumbo-Zerr, Katrin; Lin, Neng Yu; Distler, Alfiya; Gelse, Kolja; Varga, John; Distler, Oliver; Schett, Georg; Distler, Jörg H W (2013). Blockade of canonical Wnt signalling ameliorates experimental dermal fibrosis. Annals of the Rheumatic Diseases, 72(7):1255-1258.

Distler, Alfiya; Deloch, Lisa; Huang, Jingang; Dees, Clara; Lin, Neng-Yu; Palumbo-Zerr, Katrin; Beyer, Christian; Weidemann, Alexander; Distler, Oliver; Schett, Georg; Distler, Jörg H W (2013). Inactivation of tankyrases reduces experimental fibrosis by inhibiting canonical Wnt signalling. Annals of the Rheumatic Diseases, 72(9):1575-1580.

Krämer, Marlene; Dees, Clara; Huang, Jingang; Schlottmann, Inga; Palumbo-Zerr, Katrin; Zerr, Pawel; Gelse, Kolja; Beyer, Christian; Distler, Alfiya; Marquez, Victor E; Distler, Oliver; Schett, Georg; Distler, Jörg H W (2013). Inhibition of H3K27 histone trimethylation activates fibroblasts and induces fibrosis. Annals of the Rheumatic Diseases, 72(4):614-620.

Akhmetshina, Alfiya; Palumbo, Katrin; Dees, Clara; Bergmann, Christina; Venalis, Paulius; Zerr, Pawel; Horn, Angelika; Kireva, Trayana; Beyer, Christian; Zwerina, Jochen; Schneider, Holm; Sadowski, Anika; Riener, Marc-Oliver; MacDougald, Ormond A; Distler, Oliver; Schett, Georg; Distler, Jörg H W (2012). Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis. Nature Communications, 3:735.

Zerr, Pawel; Distler, Alfiya; Palumbo-Zerr, Katrin; Tomcik, Michal; Vollath, Stefan; Dees, Clara; Egberts, Friederike; Tinazzi, Ilaria; Del Galdo, Francesco; Distler, Oliver; Schett, Georg; Spriewald, Bernd M; Distler, Jörg H W (2012). Combined inhibition of c-Abl and PDGF receptors for prevention and treatment of murine sclerodermatous chronic graft-versus-host disease. American Journal of Pathology, 181(5):1672-1680.

Gerlag, Danielle M; Raza, Karim; van Baarsen, Lisa G M; Brouwer, Elisabeth; Buckley, Christopher D; Burmester, Gerd R; Gabay, Cem; Catrina, Anca I; Cope, Andrew P; Cornelis, François; Dahlqvist, Solbritt Rantapää; Emery, Paul; Eyre, Stephen; Finckh, Axel; Gay, Steffen; Hazes, Johanna M; van der Helm-van Mil, Annette; Huizinga, Tom W J; Klareskog, Lars; Kvien, Tore K; Lewis, Cathryn; Machold, Klaus P; Rönnelid, Johan; Schaardenburg, Dirkjan van; Schett, Georg; Smolen, Josef S; Thomas, Sue; Worthington, Jane; Tak, Paul P (2012). EULAR recommendations for terminology and research in individuals at risk of rheumatoid arthritis: report from the Study Group for Risk Factors for Rheumatoid Arthritis. Annals of the Rheumatic Diseases, 71(5):638-641.

Maurer, Britta; Reich, Nicole; Juengel, Astrid; Kriegsmann, Jörg; Gay, Renate E; Schett, Georg; Michel, Beat A; Gay, Steffen; Distler, Jörg H W; Distler, Oliver (2012). Fra-2 transgenic mice as a novel model of pulmonary hypertension associated with systemic sclerosis. Annals of the Rheumatic Diseases, 71(8):1382-1387.

Horn, Angelika; Palumbo, Katrin; Cordazzo, Cinzia; Dees, Clara; Akhmetshina, Alfiya; Tomcik, Michal; Zerr, Pawel; Avouac, Jerome; Gusinde, Johannes; Zwerina, Jochen; Roudaut, Hermine; Traiffort, Elisabeth; Ruat, Martial; Distler, Oliver; Schett, Georg; Distler, Jörg H W (2012). Hedgehog signaling controls fibroblast activation and tissue fibrosis in systemic sclerosis. Arthritis and Rheumatism, 64(8):2724-2733.

Palumbo-Zerr, Katrin; Horn, Angelika; Distler, Alfiya; Zerr, Pawel; Dees, Clara; Beyer, Christian; Selvi, Enrico; Cravatt, Benjamin F; Distler, Oliver; Schett, Georg; Distler, Jörg H W (2012). Inactivation of fatty acid amide hydrolase exacerbates experimental fibrosis by enhanced endocannabinoid-mediated activation of CB1. Annals of the Rheumatic Diseases, 71(12):2051-2054.

Zerr, Pawel; Palumbo-Zerr, Katrin; Distler, Alfiya; Tomcik, Michal; Vollath, Stefan; Munoz, Luis E; Beyer, Christian; Dees, Clara; Egberts, Friederike; Tinazzi, Ilaria; Del Galdo, Francesco; Distler, Oliver; Schett, Georg; Spriewald, Bernd M; Distler, Jörg H W (2012). Inhibition of hedgehog signaling for the treatment of murine sclerodermatous chronic graft-versus-host disease. Blood, 120(14):2909-2917.

Horn, Angelika; Kireva, Trayana; Palumbo-Zerr, Katrin; Dees, Clara; Tomcik, Michal; Cordazzo, Cinzia; Zerr, Pawel; Akhmetshina, Alfiya; Ruat, Martial; Distler, Oliver; Beyer, Christian; Schett, Georg; Distler, Jörg H W (2012). Inhibition of hedgehog signalling prevents experimental fibrosis and induces regression of established fibrosis. Annals of the Rheumatic Diseases, 71(5):785-789.

Khodzhigorova, Aisa; Distler, Alfiya; Lang, Veronika; Dees, Clara; Schneider, Holm; Beyer, Christian; Gelse, Kolja; Distler, Oliver; Schett, Georg; Distler, Jörg H W (2012). Inhibition of sumoylation prevents experimental fibrosis. Annals of the Rheumatic Diseases, 71(11):1904-1908.

Dees, Clara; Tomcik, Michal; Palumbo-Zerr, Katrin; Akhmetshina, Alfiya; Beyer, Christian; Lang, Veronika; Horn, Angelika; Zerr, Pawel; Zwerina, Jochen; Gelse, Kolja; Distler, Oliver; Schett, Georg; Distler, Jörg H W (2012). JAK2 as a novel mediator of the pro-fibrotic effects of TGFβ in systemic sclerosis. Arthritis and Rheumatism, 64(9):3006-3015.

Reich, Nicole; Tomcik, Michal; Zerr, Pawel; Lang, Veronika; Dees, Clara; Avouac, Jérome; Palumbo, Katrin; Horn, Angelika; Akhmetshina, Alfiya; Beyer, Christian; Xie, Weilin; Bennett, Brydon L; Distler, Oliver; Schett, Georg; Distler, Jörg H W (2012). Jun N-terminal kinase as a potential molecular target for prevention and treatment of dermal fibrosis. Annals of the Rheumatic Diseases, 71(5):737-745.

Weingärtner, Simon; Zerr, Pawel; Tomcik, Michal; Palumbo-Zerr, Katrin; Distler, Alfiya; Dees, Clara; Beyer, Christian; Shankar, Sai L; Cedzik, Dorota; Schafer, Peter H; Distler, Oliver; Schett, Georg; Distler, Jörg H W (2012). Pomalidomide is effective for prevention and treatment of experimental skin fibrosis. Annals of the Rheumatic Diseases, 71(11):1895-1899.

Beyer, Christian; Reich, Nicole; Schindler, Sonia C; Akhmetshina, Alfiya; Dees, Clara; Tomcik, Michal; Hirth-Dietrich, Claudia; von Degenfeld, Georges; Sandner, Peter; Distler, Oliver; Schett, Georg; Distler, Jörg H W (2012). Stimulation of soluble guanylate cyclase reduces experimental dermal fibrosis. Annals of the Rheumatic Diseases, 71(6):1019-1026.

Krönke, Gerhard; Reich, Nicole; Scholtysek, Carina; Akhmetshina, Alfiya; Uderhardt, Stefan; Zerr, Pawel; Palumbo, Katrin; Lang, Veronika; Dees, Clara; Distler, Oliver; Schett, Georg; Distler, Jörg H W (2012). The 12/15-lipoxygenase pathway counteracts fibroblast activation and experimental fibrosis. Annals of the Rheumatic Diseases, 71(6):1081-1087.

Beyer, Christian; Schramm, Amelie; Akhmetshina, Alfiya; Dees, Clara; Kireva, Trayana; Gelse, Kolja; Sonnylal, Sonali; de Crombrugghe, Benoit; Taketo, Makoto Mark; Distler, Oliver; Schett, Georg; Distler, Jörg H W (2012). β-catenin is a central mediator of pro-fibrotic Wnt signaling in systemic sclerosis. Annals of the Rheumatic Diseases, 71(5):761-767.

This list was generated on Fri Nov 24 14:11:22 2017 CET.