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Number of items: 24.

Perrotta, S; Stiehl, D P; Punzo, F; Scianguetta, S; Borriello, A; Bencivenga, D; Casale, M; Nobili, B; Fasoli, S; Balduzzi, A; Cro, L; Nytko, K J; Wenger, R H; Della Ragione, F (2013). Congenital erythrocytosis associated with gain-of-function HIF2A gene mutations and erythropoietin levels in the normal range. Haematologica:1-34.

Stiehl, D P. Integral action of hypoxia-inducible HIF prolyl-4-hydroxylases in mammalian oxygen sensing. 2012, University of Zurich, Faculty of Medicine.

Stiehl, D P; Bordoli, M R; Abreu-Rodríguez, I; Wollenick, K; Schraml, P; Gradin, K; Poellinger, L; Kristiansen, G; Wenger, R H (2012). Non-canonical HIF-2alpha function drives autonomous breast cancer cell growth via an AREG-EGFR/ErbB4 autocrine loop. Oncogene, 31(18):2283-2297.

Nytko, K J; Stiehl, D P; Wenger, R H (2012). PHD oxygen sensor function and antioxidants. In: Pastorekova, Silvia; Kopacek, Juraj. Tumor Hypoxia: Molecular Mechanisms and Clinical Implications. Frankfurt am Main: PETER LANG; VEDA, 127-155.

Wollenick, K; Hu, J; Kristiansen, G; Schraml, P; Rehrauer, H; Berchner-Pfannschmidt, U; Fandrey, J; Wenger, R H; Stiehl, D P (2012). Synthetic transactivation screening reveals ETV4 as broad coactivator of hypoxia-inducible factor signaling. Nucleic Acids Research, 40(5):1928-1943.

Kristiansen, G; Hu, J; Wichmann, D; Stiehl, D P; Rose, M; Gerhardt, J; Bohnert, A; Ten Haaf, A; Moch, H; Raleigh, J; Varia, M A; Subarsky, P; Scandurra, F M; Gnaiger, E; Gleixner, E; Bicker, A; Gassmann, M; Hankeln, T; Dahl, E; Gorr, T A (2011). Endogenous myoglobin in breast cancer is hypoxia-inducible by alternative transcription and functions to impair mitochondrial activity: a role in tumor suppression? Journal of Biological Chemistry, 286(50):43417-43428.

Hu, J; Stiehl, D P; Setzer, C; Wichmann, D; Shinde, D A; Rehrauer, H; Hradecky, P; Gassmann, M; Gorr, T A (2011). Interaction of HIF and USF signaling pathways at human genes flanked by hypoxia-response elements and E-box palindromes. Molecular Cancer Research, 9(11):1520-1536.

Bordoli, M R; Stiehl, D P; Borsig, L; Kristiansen, G; Hausladen, S; Schraml, P; Wenger, R H; Camenisch, G (2011). Prolyl-4-hydroxylase PHD2- and hypoxia-inducible factor 2-dependent regulation of amphiregulin contributes to breast tumorigenesis. Oncogene, 30(5):548-560.

Chen, N; Rinner, O; Czernik, D; Nytko, K J; Zheng, D; Stiehl, D P; Zamboni, N; Gstaiger, M; Frei, C (2011). The oxygen sensor PHD3 limits glycolysis under hypoxia via direct binding to pyruvate kinase. Cell Research, 21(6):983-986.

Nytko, K J; Nobuyo, M; Schlaefli, P; Spielmann, P; Wenger, R H; Stiehl, D P (2011). Vitamin C is dispensable for oxygen sensing in vivo. Blood, 117(20):5485-5493.

Neusser, M A; Lindenmeyer, M T; Moll, A G; Segerer, S; Edenhofer, I; Sen, K; Stiehl, D P; Kretzler, M; Gröne, H J; Schlöndorff, D; Cohen, C D (2010). Human nephrosclerosis triggers a hypoxia-related glomerulopathy. American Journal of Pathology, 176(2):594-607.

Wenger, R H; Camenisch, G; Stiehl, D P; Katschinski, D M (2009). HIF Prolyl-4-hydroxylase Interacting Proteins: Consequences for Drug Targeting. Current Pharmaceutical Design, 15(33):3886-3894.

Lehmann, S; Stiehl, D P; Honer, M; Dominietto, M; Keist, R; Kotevic, I; Wollenick, K; Ametamey, S; Wenger, R H; Rudin, M (2009). Longitudinal and multimodal in vivo imaging of tumor hypoxia and its downstream molecular events. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 106(33):14004-14009.

Balamurugan, K; Luu, V D; Kaufmann, M R; Hofmann, V S; Boysen, G; Barth, S; Bordoli, M R; Stiehl, D P; Moch, H; Schraml, P; Wenger, R H; Camenisch, G (2009). Onconeuronal cerebellar degeneration-related antigen, Cdr2, is strongly expressed in papillary renal cell carcinoma and leads to attenuated hypoxic response. Oncogene:1-12.

Wirthner, R; Wrann, S; Balamurugan, K; Wenger, R H; Stiehl, D P (2008). Impaired DNA double-strand break repair contributes to chemoresistance in HIF-1-alpha-deficient mouse embryonic fibroblasts. Carcinogenesis, 29(12):2306-2316.

Wirthner, R; Balamurugan, K; Stiehl, D P; Barth, S; Spielmann, P; Oehme, F; Flamme, I; Katschinski, D M; Wenger, R H; Camenisch, G (2007). Determination and modulation of prolyl-4-hydroxylase domain oxygen sensor activity. Methods in Enzymology, 435:43-60.

Eckhardt, K; Troger, J; Reissmann, J; Katschinski, D M; Wagner, K F; Stengel, P J; Paasch, U; Hunziker, P; Borter, E; Barth, S; Schlafli, P; Spielmann, P; Stiehl, D P; Camenisch, G; Wenger, R H (2007). Male germ cell expression of the PAS domain kinase PASKIN and its novel target eukaryotic translation elongation factor eEF1A1. Cellular Physiology and Biochemistry, 20(1-4):227-240.

Köditz, J; Nesper, J; Wottawa, M; Stiehl, D P; Camenisch, G; Franke, C; Myllyharju, J; Wenger, R H; Katschinski, D M (2007). Oxygen-dependent ATF-4 stability is mediated by the PHD3 oxygen sensor. Blood, 110(10):3610-3617.

Nytko, K J; Spielmann, P; Camenisch, G; Wenger, R H; Stiehl, D P (2007). Regulated Function of the Prolyl-4-Hydroxylase Domain (PHD) Oxygen Sensor Proteins. Antioxidants & Redox Signaling, 9(9):1329-1338.

Barth, S; Nesper, J; Hasgall, P A; Wirthner, R; Nytko, K J; Edlich, F; Katschinski, D M; Stiehl, D P; Wenger, R H; Camenisch, G (2007). The peptidyl prolyl cis/trans isomerase FKBP38 determines hypoxia-inducible transcription factor prolyl-4-hydroxylase PHD2 protein stability. Molecular and Cellular Biology, 27(10):3758-3768.

Stiehl, D P; Wirthner, R; Köditz, J; Spielmann, P; Camenisch, G; Wenger, R H (2006). Increased prolyl 4-hydroxylase domain proteins compensate for decreased oxygen levels. Evidence for an autoregulatory oxygen-sensing system. Journal of Biological Chemistry, 281(33):23482-23491.

Ibrahim, N O; Hahn, T; Franke, C; Stiehl, D P; Wirthner, R; Wenger, R H; Katschinski, D M (2005). Induction of the hypoxia-inducible factor system by low levels of heat shock protein 90 inhibitors. Cancer Research, 65(23):11094-11100.

Wenger, R H; Stiehl, D P; Camenisch, G (2005). Integration of oxygen signaling at the consensus HRE. Science Signaling, 2005(306):re12.

Stiehl, D P; Jelkmann, W; Wenger, R H; Hellwig-Bürgel, T (2002). Normoxic induction of the hypoxia-inducible factor 1alpha by insulin and interleukin-1beta involves the phosphatidylinositol 3-kinase pathway. FEBS Letters, 512(1-3):157-162.

This list was generated on Wed Sep 19 00:57:56 2018 CEST.