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Number of items: 11.

Mandhapati, Appi Reddy; Yang, Guanyu; Kato, Takayuki; Shcherbakov, Dimitri; Hobbie, Sven N; Vasella, Andrea; Böttger, Erik C; Crich, David (2017). Structure-Based Design and Synthesis of Apramycin-Paromomycin Analogues: Importance of the Configuration at the 6'-Position and Differences between the 6'-Amino and Hydroxy Series. Journal of the American Chemical Society, 139(41):14611-14619.

Sati, Girish C; Shcherbakov, Dimitri; Hobbie, Sven N; Vasella, Andrea; Böttger, Erik C; Crich, David (2017). N6', N6''', and O4' Modifications to Neomycin Affect Ribosomal Selectivity without Compromising Antibacterial Activity. ACS Infectious Diseases, 3(5):368-377.

Matsushita, Takahiko; Chen, Weiwei; Juskeviciene, Reda; Teo, Youjin; Shcherbakov, Dimitri; Vasella, Andrea; Böttger, Erik C; Crich, David (2015). Influence of 4'-O-Glycoside Constitution and Configuration on Ribosomal Selectivity of Paromomycin. Journal of the American Chemical Society, 137(24):7706-7717.

Mandhapati, Appi Reddy; Kato, Takayuki; Matsushita, Takahiko; Ksebati, Bashar; Vasella, Andrea; Böttger, Erik C; Crich, David (2015). Fluorine-decoupled carbon spectroscopy for the determination of configuration at fully substituted, trifluoromethyl- and perfluoroalkyl-bearing carbons: comparison with 19F-1H heteronuclear Overhauser effect spectroscopy. Journal of Organic Chemistry, 80(3):1754-1763.

Mandhapati, Appi Reddy; Shcherbakov, Dimitri; Duscha, Stefan; Vasella, Andrea; Böttger, Erik C; Crich, David (2014). Importance of the 6'-hydroxy group and its configuration for apramycin activity. ChemMedChem, 9(9):2074-2083.

Perez-Fernandez, Déborah; Shcherbakov, Dmitri; Matt, Tanja; Leong, Ng Chyan; Kudyba, Iwona; Duscha, Stefan; Boukari, Heithem; Patak, Rashmi; Dubbaka, Srinivas Reddy; Lang, Kathrin; Meyer, Martin; Akbergenov, Rashid; Freihofer, Pietro; Vaddi, Swapna; Thommes, Pia; Ramakrishnan, V; Vasella, Andrea; Böttger, Erik C (2014). 4'-O-substitutions determine selectivity of aminoglycoside antibiotics. Nature Communications, 5:3112.

Duscha, Stefan; Boukari, Heithem; Shcherbakov, Dimitri; Salian, Sumantha; Silva, Sandrina; Kendall, Ann; Kato, Takayuki; Akbergenov, Rashid; Perez-Fernandez, Deborah; Bernet, Bruno; Vaddi, Swapna; Thommes, Pia; Schacht, Jochen; Crich, David; Vasella, Andrea; Böttger, Erik C (2014). Identification and evaluation of improved 4'-O-(alkyl) 4,5-disubstituted 2-deoxystreptamines as next-generation aminoglycoside antibiotics. mBio, 5(5):e01827-e01814.

Chen, Weiwei; Matsushita, Takahiko; Shcherbakov, Dimitri; Boukari, Heithem; Vasella, Andrea; Böttger, Erik C; Crich, David (2014). Synthesis, antiribosomal and antibacterial activity of 4'-O-glycopyranosyl paromomycin aminoglycoside antibiotics. MedChemComm, 5:1179-1187.

Matt, Tanja; Ng, Chyan Leong; Lang, Kathrin; Sha, Su-Hua; Akbergenov, Rashid; Shcherbakov, Dmitri; Meyer, Martin; Duscha, Stefan; Xie, Jing; Dubbaka, Srinivas R; Perez-Fernandez, Déborah; Vasella, Andrea; Ramakrishnan, V; Schacht, Jochen; Böttger, Erik C (2012). Dissociation of antibacterial activity and aminoglycoside ototoxicity in the 4-monosubstituted 2-deoxystreptamine apramycin. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 109(27):10984-10989.

Salian, Sumantha; Matt, Tanja; Akbergenov, Rashid; Harish, Shinde; Meyer, Martin; Duscha, Stefan; Shcherbakov, Dmitri; Bernet, Bruno B; Vasella, Andrea; Westhof, Eric; Böttger, Erik C (2012). Structure-activity relationships among the kanamycin aminoglycosides: role of ring I hydroxy and amino groups. Antimicrobial Agents and Chemotherapy, 56(12):6104-6108.

Pathak, Rashmi; Perez-Fernandez, Déborah; Nandurdikar, Rahul; Kalapala, Sarath K; Böttger, Erik C; Vasella, Andrea (2008). Synthesis and evaluation of paromomycin derivates modified at C(4'). Helvetica Chimica Acta, 91(8):1533-1552.

This list was generated on Fri Aug 17 08:18:45 2018 CEST.