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Aguzzi, Adriano (2017). Strong, generous support for medical research emerges from a large cohort of Swiss patients. Swiss Medical Weekly, 147:w14537.

Leske, Henning; Brandal, Petter; Rushing, Elisabeth J; Niehusmann, Pitt (2017). IDH-mutant giant cell glioblastoma: A neglected tumor variant? Clinical Neuropathology, 36(11):293-295.

Pfammatter, Manuela; Andreasen, Maria; Meisl, Georg; Taylor, Christopher G; Adamcik, Jozef; Bolisetty, Sreenath; Sanchez-Ferrer, Antoni; Klenerman, David; Dobson, Christopher M; Mezzenga, Raffaele; Knowles, Tuomas P J; Aguzzi, Adriano A; Hornemann, Simone (2017). Absolute Quantification of Amyloid Propagons by Digital Microfluidics. Analytical Chemistry:Epub ahead of print.

Seredenina, T; Sorce, S; Herrmann, F R; Ma Mulone, X-J; Plastre, O; Aguzzi, A; Jaquet, V; Krause, K-H (2017). Decreased NOX2 expression in the brain of patients with bipolar disorder: association with valproic acid prescription and substance abuse. Translational Psychiatry, 7(8):e1206.

Sorce, Silvia; Stocker, Roland; Seredenina, Tamara; Holmdahl, Rikard; Aguzzi, Adriano; Chio, Adriano; Depaulis, Antoine; Heitz, Freddy; Olofsson, Peter; Olsson, Tomas; Duveau, Venceslas; Sanoudou, Despina; Skosgater, Sara; Vlahou, Antonia; Wasquel, Dominique; Krause, Karl-Heinz; Jaquet, Vincent (2017). NADPH oxidases as drug targets and biomarkers in neurodegenerative diseases: what is the evidence? Free Radical Biology & Medicine, 112:387-396.

Kirschenbaum, Daniel; Prömmel, Peter; Vasella, Flavio; Haralambieva, Eugenia; Marques Maggio, Ewerton; Reisch, Robert; Beer, Marc; Camenisch, Ulrike; Rushing, Elisabeth J (2017). Fibrin-associated diffuse large B-cell lymphoma in a hemorrhagic cranial arachnoid cyst. Acta Neuropathologica Communications, 5:60.

Nuvolone, Mario; Paolucci, Marta; Sorce, Silvia; Kana, Veronika; Moos, Rita; Matozaki, Takashi; Aguzzi, Adriano (2017). Prion pathogenesis is unaltered in the absence of SIRPα-mediated "don't-eat-me" signaling. PLoS ONE, 12(5):e0177876.

Wulf, Marie-Angela; Senatore, Assunta; Aguzzi, Adriano (2017). The biological function of the cellular prion protein: an update. BMC Biology, 15:34.

Kovacs, Gabor G; Rahimi, Jasmin; Ströbel, Thomas; Lutz, Mirjam I; Regelsberger, Günther; Streichenberger, Nathalie; Perret-Liaudet, Armand; Höftberger, Romana; Liberski, Pawel P; Budka, Herbert; Sikorska, Beata (2017). Tau Pathology in Creutzfeldt-Jakob Disease Revisited. Brain Pathology, 27(3):332-344.

Myers, Kenneth A; Mandelstam, Simone A; Ramantani, Georgia; Rushing, Elisabeth J; de Vries, Bert B; Koolen, David A; Scheffer, Ingrid E (2017). The epileptology of Koolen-de Vries syndrome: Electro-clinico-radiologic findings in 31 patients. Epilepsia, 58(6):1085-1094.

Velz, Julia; Neidert, Marian Christoph; Bozinov, Oliver; Grotzer, Michael; Kirschenbaum, Daniel; Rushing, Elisabeth J (2017). Isolated intracerebral Langerhans cell histiocytosis with multifocal lesions. Pediatric Blood & Cancer, 64(11):e26546.

Nuvolone, Mario; Sorce, Silvia; Paolucci, Marta; Aguzzi, Adriano (2017). Extended characterization of the novel co-isogenic C57BL/6J Prnp$^{−/−}$ mouse line. Amyloid, 24(Suppl 1):36-37.

Ballmer, Boris A; Moos, Rita; Liberali, Prisca; Pelkmans, Lucas; Hornemann, Simone; Aguzzi, Adriano (2017). Modifiers of prion protein biogenesis and recycling identified by a highly-parallel endocytosis kinetics assay. Journal of Biological Chemistry, 292(20):8356-8368.

Nuvolone, Mario; Sorce, Silvia; Pelczar, Pawel; Rushing, Elisabeth; Lavatelli, Francesca; Rognoni, Paola; Valentini, Veronica; Palladini, Giovanni; Merlini, Giampaolo; Aguzzi, Adriano (2017). Regulated expression of amyloidogenic immunoglobulin light chains in mice. Amyloid, 24(Suppl 1):52-53.

Neidert, Marian C; Leske, Henning; Frontzek, Karl; Bode, Beata; Capper, David; Regli, Luca; Rushing, Elisabeth J (2017). A 49-year old female with multiple extra-axial tumors. Brain Pathology, 27(2):235-236.

Barrantes-Freer, Alonso; Engel, Aylin Sophie; Rodríguez-Villagra, Odir Antonio; Winkler, Anne; Bergmann, Markus; Mawrin, Christian; Kuempfel, Tania; Pellkofer, Hannah; Metz, Imke; Bleckmann, Annalen; Hernández-Durán, Silvia; Schippling, Sven; Rushing, Elisabeth J; Frank, Stephan; Glatzel, Markus; Matschke, Jakob; Hartmann, Christian; Reifenberger, Guido; Müller, Wolf; Schildhaus, Hans-Ulrich; Brück, Wolfgang; Stadelmann, Christine (2017). Diagnostic red flags: steroid-treated malignant CNS lymphoma mimicking autoimmune inflammatory demyelination. Brain Pathology:Epub ahead of print.

Leske, Henning; Hornemann, Simone; Herrmann, Uli Simon; Zhu, Caihong; Dametto, Paolo; Li, Bei; Laferriere, Florent; Polymenidou, Magdalini; Pelczar, Pawel; Reimann, Regina Rose; Schwarz, Petra; Rushing, Elisabeth Jane; Wüthrich, Kurt; Aguzzi, Adriano (2017). Protease resistance of infectious prions is suppressed by removal of a single atom in the cellular prion protein. PLoS ONE, 12(2):e0170503.

Nuvolone, Mario; Schmid, Nicolas; Miele, Gino; Sorce, Silvia; Moos, Rita; Schori, Christian; Beerli, Roger R; Bauer, Monika; Saudan, Philippe; Dietmeier, Klaus; Lachmann, Ingolf; Linnebank, Michael; Martin, Roland; Kallweit, Ulf; Kana, Veronika; Rushing, Elisabeth J; Budka, Herbert; Aguzzi, Adriano (2017). Cystatin F is a biomarker of prion pathogenesis in mice. PLoS ONE, 12(2):e0171923.

Kiessling, Michael K; Curioni-Fontecedro, Alessandra; Samaras, Panagiotis; Lang, Silvia; Scharl, Michael; Aguzzi, Adriano; Oldridge, Derek A; Maris, John M; Rogler, Gerhard (2017). Correction: Targeting the mTOR Complex by Everolimus in NRAS Mutant Neuroblastoma. PLoS ONE, 12(1):e0170851.

Bethge, Philipp; Carta, Stefano; Lorenzo, Dayra A; Egolf, Ladan; Goniotaki, Despoina; Madisen, Linda; Voigt, Fabian F; Chen, Jerry L; Schneider, Bernard; Ohkura, Masamichi; Nakai, Junichi; Zeng, Hongkui; Aguzzi, Adriano; Helmchen, Fritjof (2017). An R-CaMP1.07 reporter mouse for cell-type-specific expression of a sensitive red fluorescent calcium indicator. PLoS ONE, 12(6):e0179460.

Bossart, Simon; Thurneysen, Selina; Rushing, Elisabeth; Frontzek, Karl; Leske, Henning; Mihic‐Probst, Daniela; Nagel, Hannes W; Mangana, Johanna; Goldinger, Simone M; Dummer, Reinhard (2017). Case Report: Encephalitis, with Brainstem Involvement, Following Checkpoint Inhibitor Therapy in Metastatic Melanoma. The oncologist, 22(6):749-753.

Frese, Sebastian; Petersen, Jens A; Ligon-Auer, Maria; Mueller, Sandro Manuel; Mihaylova, Violeta; Gehrig, Saskia M; Kana, Veronika; Rushing, Elisabeth J; Unterburger, Evelyn; Kägi, Georg; Burgunder, Jean-Marc; Toigo, Marco; Jung, Hans H (2017). Exercise effects in Huntington disease. Journal of Neurology, 264(1):32-39.

Aguzzi, Adriano; Zhu, Caihong (2017). Microglia in prion diseases. Journal of Clinical Investigation:JCI90605.

Kovacs, Gabor G; Ferrer, Isidro; Grinberg, Lea T; Alafuzoff, Irina; Attems, Johannes; Budka, Herbert; Cairns, Nigel J; Crary, John F; Duyckaerts, Charles; Ghetti, Bernardino; Halliday, Glenda M; Ironside, James W; Love, Seth; Mackenzie, Ian R; Munoz, David G; Murray, Melissa E; Nelson, Peter T; Takahashi, Hitoshi; Trojanowski, John Q; Ansorge, Olaf; Arzberger, Thomas; Baborie, Atik; Beach, Thomas G; Bieniek, Kevin F; Bigio, Eileen H; Bodi, Istvan; Dugger, Brittany N; Feany, Mel; Gelpi, Ellen; Gentleman, Stephen M; et al (2016). Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy. Acta Neuropathologica, 131(1):87-102.

Li, Bei. Establishment of An Automated Digital Prion Infectivity Cell Assay and PrP-HPFRET Based High-throughput siRNA Screening Platform. 2016, University of Zurich, Faculty of Science.

Goniotaki, Despoina. Inhibition of Group I Metabotropic Glutamate Receptors (mGluR1 and mGluR5) Protects Against Prion-Induced Toxicity. 2016, University of Zurich, Faculty of Science.

Frontzek, Karl; Pfammatter, Manuela; Sorce, Silvia; Senatore, Assunta; Schwarz, Petra; Moos, Rita; Frauenknecht, Katrin; Hornemann, Simone; Aguzzi, Adriano (2016). Neurotoxic antibodies against the prion protein do not trigger prion replication. PLoS ONE, 11(9):e0163601.

Sherman, M A; LaCroix, M; Amar, F; Larson, M E; Forster, C; Aguzzi, A; Bennett, D A; Ramsden, M; Lesne, S E (2016). Soluble Conformers of A and Tau Alter Selective Proteins Governing Axonal Transport. Journal of Neuroscience, 36(37):9647-9658.

Brandtner, H; Monticelli, F C; Meyer, H J; Biebl, A; Budka, H (2016). Fatal cerebral haemorrhage in a hypertensive seven-year-old boy. Journal of the Royal Society of Medicine open, 7(9):1-4.

Neidert, Marian Christoph; Regli, Luca; Rushing, Elisabeth (2016). Coexisting pituicytoma and pituitary adenoma; a second coincidence?—reply. Human Pathology, 55:205-206.

Küffer, Alexander; Lakkaraju, Asvin K. K; Mogha, Amit; Petersen, Sarah C; Airich, Kristina; Doucerain, Cédric; Marpakwar, Rajlakshmi; Bakirci, Pamela; Senatore, Assunta; Monnard, Arnaud; Schiavi, Carmen; Nuvolone, Mario; Grosshans, Bianka; Hornemann, Simone; Bassilana, Frederic; Monk, Kelly R; Aguzzi, Adriano (2016). The prion protein is an agonistic ligand of the G protein-coupled receptor Adgrg6. Nature, 536(7617):464-468.

Lehman, Norman L; Hattab, Eyas M; Mobley, Bret C; Usubalieva, Aisulu; Schniederjan, Matthew J; McLendon, Roger E; Paulus, Werner; Rushing, Elisabeth J; Georgescu, Maria-Magdalena; Couce, Marta; Dulai, Mohanpal S; Cohen, Mark L; Pierson, Christopher R; Raisanen, Jack M; Martin, Sarah E; Lehman, Trang D; Lipp, Eric S; Bonnin, Jose M; Al-Abbadi, Mousa A; Kenworthy, Kara; Zhao, Kevin; Mohamed, Nehad; Zhang, Guojuan; Zhao, Weiqiang (2016). Morphological and molecular features of astroblastoma, including BRAFV600E mutations, suggest an ontological relationship to other cortical-based gliomas of children and young adults. Neuro-Oncology, 19(1):31-42.

Gelpi, Ellen; Höftberger, Romana; Graus, Francesc; Ling, Helen; Holton, Janice L; Dawson, Timothy; Popovic, Mara; Pretnar-Oblak, Janja; Högl, Birgit; Schmutzhard, Erich; Poewe, Werner; Ricken, Gerda; Santamaria, Joan; Dalmau, Josep; Budka, Herbert; Revesz, Tamas; Kovacs, Gabor G (2016). Neuropathological criteria of anti-IgLON5-related tauopathy. Acta Neuropathologica, 132(4):531-543.

Einsiedler, Melanie. Investigation of the Role of Glial Cells in Prion Toxicity and a Potential Function of PrPC as a Cell Death Transducer. 2016, University of Zurich, Faculty of Science.

Requena, Jesús R; Kristensson, Krister; Korth, Carsten; Zurzolo, Chiara; Simmons, Marion; Aguilar-Calvo, Patricia; Aguzzi, Adriano; Andreoletti, Olivier; Benestad, Sylvie L; Böhm, Reinhard; Brown, Karen; Calgua, Byron; del Río, José Antonio; Espinosa, Juan Carlos; Girones, Rosina; Godsave, Sue; Hoelzle, Ludwig E; Knittler, Michael R; Kuhn, Franziska; Legname, Giuseppe; Laeven, Paul; Mabbott, Neil; Mitrova, Eva; Müller-Schiffmann, Andreas; Nuvolone, Mario; Peters, Peter J; Raeber, Alex; Roth, Klaus; Schmitz, Matthias; Schroeder, Björn; Sonati, Tiziana; Stitz, Lothar; Taraboulos, Albert; Torres, Juan María; Yan, Zheng-Xin; Zerr, Inga (2016). The Priority position paper: protecting Europe´s food chain from prions. Prion, 10(3):165-181.

Zhu, Caihong; Herrmann, Uli S; Falsig, Jeppe; Abakumova, Irina; Nuvolone, Mario; Schwarz, Petra; Frauenknecht, Katrin; Rushing, Elisabeth J; Aguzzi, Adriano (2016). A neuroprotective role for microglia in prion diseases. Journal of Experimental Medicine, 213(6):1047-1059.

Forny, Patrick; Schumann, Anke; Mustedanagic, Merima; Mathis, Déborah; Wulf, Marie-Angela; Nägele, Nadine; Langhans, Claus-Dieter; Zhakupova, Assem; Heeren, Joerg; Scheja, Ludger; Fingerhut, Ralph; Peters, Heidi L; Hornemann, Thorsten; Thony, Beat; Kölker, Stefan; Burda, Patricie; Froese, D Sean; Devuyst, Olivier; Baumgartner, Matthias R (2016). Novel mouse models of methylmalonic aciduria recapitulate phenotypic traits with a genetic dosage effect. Journal of Biological Chemistry, 291(39):20563-20573.

Klein, Klaus U; Johannes, Amelie; Brückner, Melanie; Thomas, Rainer; Matthews, Stephan; Frauenknecht, Katrin; Leukel, Petra; Mazur, Johanna; Poplawski, Alicia; Muellenbach, Ralf; Sommer, Clemens J; Thal, Serge C; Engelhard, Kristin (2016). Systemic PaO2 oscillations cause mild brain injury in a pig model. Critical Care Medicine, 44(5):e253-e263.

Seystahl, Katharina; Stoecklein, Veit; Schüller, Ulrich; Rushing, Elisabeth; Nicolas, Guillaume; Schäfer, Niklaus; Ilhan, Harun; Pangalu, Athina; Weller, Michael; Tonn, Jörg-Christian; Sommerauer, Michael; Albert, Nathalie L (2016). Somatostatin-receptor-targeted radionuclide therapy for progressive meningioma: benefit linked to 68Ga-DOTATATE/-TOC uptake. Neuro-Oncology, 18(11):1538-1547.

Gramatzki, Dorothee; Dehler, Silvia; Rushing, Elisabeth Jane; Zaugg, Kathrin; Hofer, Silvia; Yonekawa, Yasuhiro; Bertalanffy, Helmut; Valavanis, Anton; Korol, Dimitri; Rohrmann, Sabine; Pless, Miklos; Oberle, Joachim; Roth, Patrick; Ohgaki, Hiroko; Weller, Michael (2016). Glioblastoma in the canton of Zurich, Switzerland revisited: 2005 to 2009. Cancer, 122(14):2206-2215.

Aguzzi, Adriano; Altmeyer, Matthias (2016). Phase separation: linking cellular compartmentalization to disease. Trends in Cell Biology, 26(7):547-558.

Kovacs, Gabor G; Lutz, Mirjam I; Ricken, Gerda; Ströbel, Thomas; Höftberger, Romana; Preusser, Matthias; Regelsberger, Günther; Hönigschnabl, Selma; Reiner, Angelika; Fischer, Peter; Budka, Herbert; Hainfellner, Johannes A (2016). Dura mater is a potential source of Aβ seeds. Acta Neuropathologica, 131(6):911-923.

Theocharides, Alexandre P; Lundberg, Pontus; Lakkaraju, Asvin K K; Lysenko, Veronika; Myburgh, Renier; Aguzzi, Adriano; Skoda, Radek C; Manz, Markus G (2016). Homozygous Calreticulin mutations in patients with myelofibrosis lead to acquired myeloperoxidase deficiency. Blood, 127(25):3253-3259.

Szabo, E; Schneider, H; Seystahl, K; Rushing, E J; Herting, F; Weidner, K M; Weller, M (2016). Autocrine VEGFR1 and VEGFR2 signaling promotes survival in human glioblastoma models in vitro and in vivo. Neuro-Oncology, 18(9):1242-1252.

Tschuor, Christoph; Kachaylo, Ekaterina; Limani, Përparim; Raptis, Dimitri A; Linecker, Michael; Tian, Yinghua; Herrmann, Uli; Grabliauskaite, Kamile; Weber, Achim; Columbano, Amedeo; Graf, Rolf; Humar, Bostjan; Clavien, Pierre-Alain (2016). Constitutive androstane receptor (Car)-driven regeneration protects liver from failure following tissue loss. Journal of Hepatology, 65(1):66-74.

Haybaeck, Johannes; Heikenwalder, Mathias; Klevenz, Britta; Schwarz, Petra; Margalith, Ilan; Bridel, Claire; Mertz, Kirsten; Zirdum, Elizabeta; Petsch, Benjamin; Fuchs, Thomas J; Stitz, Lothar; Aguzzi, Adriano (2016). Correction: Aerosols transmit prions to immunocompetent and immunodeficient mice. PLoS Pathogens, 12(2):e1005463.

Weller, Michael; Nabors, Louis Burt; Gorlia, Thierry; Leske, Henning; Rushing, Elisabeth; Bady, Pierre; Hicking, Christine; Perry, James; Hong, Yong-Kil; Roth, Patrick; Wick, Wolfgang; Goodman, Simon L; Hegi, Monika E; Picard, Martin; Moch, Holger; Straub, Josef; Stupp, Roger (2016). Cilengitide in newly diagnosed glioblastoma: biomarker expression and outcome. OncoTarget, 7(12):15018-15032.

Sommerauer, M; Burkhardt, J K; Frontzek, K; Rushing, E; Buck, A; Krayenbuehl, N; Weller, M; Schaefer, N; Kuhn, F P (2016). 68Gallium-DOTATATE PET in meningioma: A reliable predictor of tumor growth rate? Neuro-Oncology, 18(7):1021-1027.

Kerz, T; Beyer, C; Mole, D; Oswald, S; Frauenknecht, K; von Loewenich, F D; Schwanz, T (2016). Abszedierende Pilzenzephalitis durch C. bantiana bei einer immunsupprimierten Patientin. Der Nervenarzt, 87(2):191-194.

Frontzek, Karl; Lutz, Mirjam I; Aguzzi, Adriano; Kovacs, Gabor G; Budka, Herbert (2016). Amyloid-β pathology and cerebral amyloid angiopathy are frequent in iatrogenic Creutzfeldt-Jakob disease after dural grafting. Swiss Medical Weekly, 146:w14287.

Frauenknecht, Katrin; Diederich, Kai; Leukel, Petra; Bauer, Henrike; Schäbitz, Wolf-Rüdiger; Sommer, Clemens J; Minnerup, Jens (2016). Functional improvement after photothrombotic stroke in rats is associated with different patterns of dendritic plasticity after g-csf treatment and g-csf treatment combined with concomitant or sequential constraint-induced movement therapy. PLoS ONE, 11(1):e0146679.

Galimov, Artur; Merry, Troy L; Luca, Edlira; Rushing, Elisabeth J; Mizbani, Amir; Turcekova, Katarina; Hartung, Angelika; Croce, Carlo M; Ristow, Michael; Krützfeldt, Jan (2016). microRNA-29a in adult muscle stem cells controls skeletal muscle regeneration during injury and exercise downstream of fibroblast growth factor-2. Stem Cells, 34(3):768-780.

Gelpi, Ellen; Budka, Herbert (2016). Prion diseases. In: Lisak, R P; Truong, D D; Caroll, W M; Bhidayasiri, R. International Neurology: A Clinical Approach. Chichester: Wiley-Blackwell, 296-299.

Hofer, Silvia; Berthod, Grégoire; Riklin, Christian; Rushing, Elisabeth; Feilchenfeldt, Jonas (2016). BRAF V600E mutation: A treatable driver mutation in pleomorphic xanthoastrocytoma (PXA). Acta Oncologica, 55(1):122-123.

Aguzzi, Adriano; Lakkaraju, Asvin K K (2016). Cell biology of prions and prionoids: a status report. Trends in Cell Biology, 26(1):40-51.

Gramatzki, Dorothee; Roth, P; Felsberg, J; Hofer, S; Rushing, E J; Hentschel, B; Westphal, M; Krex, D; Simon, M; Schnell, O; Wick, W; Reifenberger, G; Weller, M (2016). Chemotherapy for intracranial ependymoma in adults. BMC Cancer, 16(1):287.

Gugger, Alenka; Barnhill, Raymond L; Seifert, Burkhardt; Dehler, Silvia; Moch, Holger; Lugassy, Claire; Marques-Maggio, Ewerton; Rushing, Elisabeth J; Mihic-Probst, Daniela (2016). Cutaneous melanoma with brain metastasis: Report of 193 patients with new observations. PLoS ONE, 11(5):e0156115.

Reimann, Regina R; Sonati, Tiziana; Hornemann, Simone; Herrmann, Uli S; Arand, Michael; Hawke, Simon; Aguzzi, Adriano (2016). Differential toxicity of antibodies to the prion protein. PLoS Pathogens, 12(1):e1005401.

Seredenina, Tamara; Nayernia, Zeynab; Sorce, Silvia; Maghzal, Ghassan J; Filippova, Aleksandra; Ling, Shuo-Chien; Basset, Olivier; Plastre, Olivier; Daali, Youssef; Rushing, Elisabeth J; Giordana, Maria T; Cleveland, Don W; Aguzzi, Adriano; Stocker, Roland; Krause, Karl-Heinz; Jaquet, Vincent (2016). Evaluation of NADPH oxidases as drug targets in a mouse model of familial amyotrophic lateral sclerosis. Free Radical Biology & Medicine, 97:95-108.

Wolpert, Fabian; Grotzer, Michael A; Niggli, Felix; Zimmermann, Dieter; Rushing, Elisabeth; Bode-Lesniewska, Beata (2016). Ewing's Sarcoma as a Second Malignancy in Long-Term Survivors of Childhood Hematologic Malignancies. Sarcoma, 2016:5043640.

Wirsching, Hans-Georg; Morel, Corinne; Gmür, Corinne; Neidert, Marian Christoph; Baumann, Christian Richard; Valavanis, Antonios; Rushing, Elisabeth Jane; Krayenbühl, Niklaus; Weller, Michael (2016). Predicting outcome of epilepsy after meningioma resection. Neuro-Oncology, 18(7):1002-1010.

Nuvolone, Mario; Hermann, Mario; Sorce, Silvia; Russo, Giancarlo; Tiberi, Cinzia; Schwarz, Petra; Minikel, Eric; Sanoudou, Despina; Pelczar, Pawel; Aguzzi, Adriano (2016). Strictly co-isogenic C57BL/6J-Prnp−/−mice: A rigorous resource for prion science. Journal of Experimental Medicine, 213(3):313-327.

Soliman, Radwa K; Budai, Caterina; Mundada, Pravin; Aljohani, Bakar; Rushing, Elisabeth J; Kollias, Spyros S (2016). Suprasellar pilocytic astrocytoma in an adult with hemorrhage and leptomeningeal dissemination: case report and review of literature. Radiology Case Reports, 11(4):411-418.

Neidert, Marian C; Leske, Henning; Burkhardt, Jan-Karl; Kollias, Spyros S; Capper, David; Schrimpf, Daniel; Regli, Luca; Rushing, Elisabeth J (2016). Synchronous pituitary adenoma and pituicytoma. Human Pathology, 47(1):138-143.

Kiessling, Michael K; Curioni-Fontecedro, Alessandra; Samaras, Panagiotis; Lang, Silvia; Scharl, Michael; Aguzzi, Adriano; Oldrige, Derek A; Maris, John M; Rogler, Gerhard (2016). Targeting the mTOR Complex by Everolimus in NRAS Mutant Neuroblastoma. PLoS ONE, 11(1):e0147682.

Silginer, M; Burghardt, I; Gramatzki, D; Bunse, L; Leske, H; Rushing, E J; Hao, N; Platten, M; Weller, M; Roth, P (2016). The aryl hydrocarbon receptor links integrin signaling to the TGF-β pathway. Oncogene, 35(25):3260-3271.

Budka, Herbert; Will, Robert G (2015). The end of the BSE saga: do we still need surveillance for human prion diseases? Swiss Medical Weekly, 145(w14212):online.

Frontzek, Karl; Moos, Rita; Schaper, Elke; Jann, Lukas; Herfs, Gregor; Zimmermann, Dieter R; Aguzzi, Adriano; Budka, Herbert (2015). Iatrogenic and sporadic Creutzfeldt-Jakob disease in 2 sisters without mutation in the prion protein gene. Prion, 9(6):444-448.

Nuvolone, Mario; Aguzzi, Adriano (2015). Altered monoaminergic systems and depressive-like behavior in congenic prion protein nnock-out mice. Journal of Biological Chemistry, 290(43):26350.

Hruska-Plochan, Marian; Li, Bei; Kyburz, Diego; Krützfeldt, Jan; Landmesser, Ulf; Aguzzi, Adriano; Polymenidou, Magdalini (2015). New and emerging roles of small RNAs in neurodegeneration, muscle, cardiovascular and inflammatory diseases. Swiss Medical Weekly:w14192.

Schreiner, Bettina; Romanelli, Elisa; Liberski, Pawel; Ingold-Heppner, Barbara; Sobottka-Brillout, Bettina; Hartwig, Tom; Chandrasekar, Vijay; Johannssen, Helge; Zeilhofer, Hanns Ulrich; Aguzzi, Adriano; Heppner, Frank; Kerschensteiner, Martin; Becher, Burkhard (2015). Astrocyte depletion impairs redox homeostasis and triggers neuronal loss in the adult CNS. Cell Reports, 12(9):1377-1384.

Reuss, David E; Kratz, Annekathrin; Sahm, Felix; Capper, David; Schrimpf, Daniel; Koelsche, Christian; Hovestadt, Volker; Bewerunge-Hudler, Melanie; Jones, David T W; Schittenhelm, Jens; Mittelbronn, Michel; Rushing, Elisabeth; Simon, Matthias; Westphal, Manfred; Unterberg, Andreas; Platten, Michael; Paulus, Werner; Reifenberger, Guido; Tonn, Joerg-Christian; Aldape, Kenneth; Pfister, Stefan M; Korshunov, Andrey; Weller, Michael; Herold-Mende, Christel; Wick, Wolfgang; Brandner, Sebastian; von Deimling, Andreas (2015). Adult IDH wild type astrocytomas biologically and clinically resolve into other tumor entities. Acta Neuropathologica, 130(3):407-417.

Baral, Pravas Kumar; Swayampakula, Mridula; Aguzzi, Adriano; James, Michael N G (2015). X-ray structural and molecular dynamical studies of the globular domains of cow, deer, elk and Syrian hamster prion proteins. Journal of Structural Biology, 192(1):37-47.

Herrmann, Uli S; Schütz, Anne K; Shirani, Hamid; Huang, Danzhi; Saban, Dino; Nuvolone, Mario; Li, Bei; Ballmer, Boris; Aslund, Andreas; Mason, Jeffrey J; Rushing, Elisabeth J; Budka, Herbert; Nystrom, Sofie; Hammarstrom, Per; Böckmann, Anja; Caflisch, Amedeo; Meier, Beat H; Nilsson, K Peter R; Hornemann, Simone; Aguzzi, Adriano (2015). Structure-based drug design identifies polythiophenes as antiprion compounds. Science Translational Medicine, 7(299):299ra123.

Könnecke, Helen K; Rushing, Elisabeth J; Neidert, Marian Christoph; Reimann, Regina; Regli, Luca; Bozinov, Oliver; Burkhardt, Jan-Karl (2015). Heterogeneous Appearance of Central Nervous System Involvement in Malignant Mixed Müllerian Tumors. Journal of Neurological Surgery. Part A: Central European Neurosurgery, 77(05):447-451.

Cudalbu, Cristina; Craveiro, Melanie; Mlynárik, Vladimir; Bremer, Juliane; Aguzzi, Adriano; Gruetter, Rolf (2015). In Vivo Longitudinal 1H MRS Study of Transgenic Mouse Models of Prion Disease in the Hippocampus and Cerebellum at 14.1 T. Neurochemical Research, 40(12):2639-2646.

Love, Seth; Perry, Arie; Budka, Herbert (2015). Greenfield's Neuropathology. Boca Raton: CRC Press.

Frei, K; Gramatzki, D; Tritschler, I; Schroeder, J J; Espinoza, L; Rushing, E J; Weller, M (2015). Transforming growth factor-β pathway activity in glioblastoma. OncoTarget, 6(8):5963-5977.

Woernle, C M; Péus, D; Hofer, S; Rushing, E J; Held, U; Bozinov, O; Krayenbühl, N; Weller, M; Regli, L (2015). Efficacy of surgery and further treatment of progressive glioblastoma. World Neurosurgery, 84(2):301-307.

Aguzzi, Adriano (2015). Authoring scientific papers: a perspective from the trenches. Swiss Medical Weekly, 145(w14107):online.

Aguzzi, Adriano (2015). Scientific publishing in the times of open access. Swiss Medical Weekly, 145(w14118):online.

Neidert, Marian Christoph; Leske, Henning; Burkhardt, Jan-Karl; Rushing, Elisabeth Jane; Bozinov, Oliver (2015). A 44-year old male with right-sided facial numbness. Dura-associated extranodal marginal zone B cell lymphoma (MALT lymphoma). Brain Pathology, 25(1):113-114.

Nuvolone, Mario; Palladini, G; Merlini, G (2015). Amyloidosis at a molecular level: General overview and focus on AL amyloidosis. In: Picken, M M; Dogan, A; Herrera, G. Amyloid and Related Disorders: Surgical Pathology and Clinical Correlations. New York: Springer Verlag, 9-29.

Blumenthal, Deborah T; Rankin, Cathryn; Stelzer, Keith J; Spence, Alexander M; Sloan, Andrew E; Moore, Dennis F; Padula, Gilbert D A; Schulman, Susan B; Wade, Mark L; Rushing, Elisabeth J (2015). A Phase III study of radiation therapy (RT) and O6-benzylguanine + BCNU versus RT and BCNU alone and methylation status in newly diagnosed glioblastoma and gliosarcoma: Southwest Oncology Group (SWOG) study S0001. International Journal of Clinical Oncology, 20(4):650-658.

Assar, H; Topakian, R; Weis, S; Rahimi, J; Trenkler, J; Hoftberger, R; Aboulenein-Djamshidian, F; Strobel, T; Budka, H; Yull, H; Head, M W; Ironside, J W; Kovacs, G G (2015). A case of variably protease-sensitive prionopathy treated with doxycyclin. Journal of Neurology, Neurosurgery, and Psychiatry, 86(7):816-818.

Sanchez-Juan, Pascual; Bishop, Matthew T; Kovacs, Gabor G; Calero, Miguel; Aulchenko, Yurii S; Ladogana, Anna; Boyd, Alison; Lewis, Victoria; Ponto, Claudia; Calero, Olga; Poleggi, Anna; Carracedo, Ángel; van der Lee, Sven J; Ströbel, Thomas; Rivadeneira, Fernando; Hofman, Albert; Haïk, Stéphane; Combarros, Onofre; Berciano, José; Uitterlinden, Andre G; Collins, Steven J; Budka, Herbert; Brandel, Jean-Philippe; Laplanche, Jean Louis; Pocchiari, Maurizio; Zerr, Inga; Knight, Richard S G; Will, Robert G; van Duijn, Cornelia M (2015). A genome wide association study links glutamate receptor pathway to sporadic Creutzfeldt-Jakob disease risk. PLoS ONE, 10(4):e0123654.

Klein, Andrea; Robb, Stephanie; Rushing, Elisabeth; Liu, Wei-Wei; Belaya, Kasiaryna; Beeson, David (2015). Congenital Myasthenic Syndrome caused by mutations in DPAGT. Neuromuscular Disorders : NMD, 25(3):253-256.

Musall, Simon; Haiss, Florent; Weber, Bruno; von der Behrens, Wolfger (2015). Deviant processing in the primary somatosensory cortex. Cerebral Cortex:Epub ahead of print.

Petersen, Jens A; Kuntzer, Thierry; Fischer, Dirk; von der Hagen, Maja; Huebner, Angela; Kana, Veronika; Lobrinus, Johannes A; Kress, Wolfram; Rushing, Elisabeth J; Sinnreich, Michael; Jung, Hans H (2015). Dysferlinopathy in Switzerland: clinical phenotypes and potential founder effects. BMC Neurology, 15(182):online.

McKinney, Nicole; Yuan, Liangping; Zhang, Hongying; Liu, Jingbo; Cho, Yoon-Jae; Rushing, Elisabeth; Schniederjan, Matthew; MacDonald, Tobey J (2015). EphrinB1 expression is dysregulated and promotes oncogenic signaling in medulloblastoma. Journal of Neuro-Oncology, 121(1):109-118.

Kros, J M; Huizer, K; Hernandez-Lain, A; Marucci, G; Michotte, A; Pollo, B; Rushing, E J; Ribalta, T; French, P; Jamine, D; Bekka, N; Lacombe, D; van den Bent, M J; Gorlia, T (2015). Evidence-based diagnostic algorithm for glioma: analysis of the results of pathology panel review and molecular parameters of EORTC 26951 and 26882 trials. Journal of Clinical Oncology, 33(17):1943-1950.

Vanlandewijck, Michael; Lebouvier, Thibaud; Andaloussi Mäe, Maarja; Nahar, Khayrun; Hornemann, Simone; Kenkel, David; Cunha, Sara I; Lennartsson, Johan; Boss, Andreas; Heldin, Carl-Henrik; Keller, Annika; Betsholtz, Christer (2015). Functional characterization of germline mutations in PDGFB and PDGFRB in primary familial brain calcification. PLoS ONE, 10(11):e0143407.

Reimann, Regina. Magnetic Resonance Imaging in the Assessment of Anti Prion Mediated Neurotoxicity In Vivo. 2015, University of Zurich, Faculty of Medicine.

Böge, Yannick Thimotheus. Mechanisms of Apoptosis-driven Carcinogenesis and Caspase 8-dependent DNA Damage Response. 2015, University of Zurich, Faculty of Medicine.

Herrmann, Uli S. Mechanisms underlying prion protein toxicity and therapeutic strategies. 2015, University of Zurich, Faculty of Medicine.

Gelpi, Ellen; Colom-Cadena, Marti; Budka, Herbert (2015). Molecular genetics of Creutzfeldt-Jakob disease and Gerstmann- Sträussler- Scheinker disease. Chichester: Wiley.

Dametto, Paolo; Lakkaraju, Asvin K K; Bridel, Claire; Villiger, Lukas; O’Connor, Tracy; Herrmann, Uli S; Pelczar, Pawel; Rülicke, Thomas; McHugh, Donal; Adili, Arlind; Aguzzi, Adriano (2015). Neurodegeneration and unfolded-protein response in mice expressing a membrane-tethered flexible tail of PrP. PLoS ONE, 10(2):e0117412.

Stenzel, W; Preusse, C; Allenbach, Y; Pehl, D; Junckerstorff, R; Heppner, F L; Nolte, K; Aronica, E; Kana, V; Rushing, E; Schneider, U; Claeys, K G; Benveniste, O; Weis, J; Goebel, H H (2015). Nuclear actin aggregation is a hallmark of anti-synthetase syndrome-induced dysimmune myopathy. Neurology, 84(13):1346-1354.

Martínez, Javier; Sánchez, Rosa; Castellanos, Milagros; Makarava, Natallia; Aguzzi, Adriano; Baskakov, Ilia V; Gasset, María (2015). PrP charge structure encodes interdomain interactions. Scientific Reports, 5:13623.

Herrmann, Uli S; Sonati, Tiziana; Falsig, Jeppe; Reimann, Regina R; Dametto, Paolo; O’Connor, Tracy; Li, Bei; Lau, Agnes; Hornemann, Simone; Sorce, Silvia; Wagner, Uli; Sanoudou, Despina; Aguzzi, Adriano (2015). Prion infections and anti-PrP antibodies trigger converging neurotoxic pathways. PLoS Pathogens, 11(2):e1004662.

Nuvolone, Mario; Sorce, Silvia; Schwarz, Petra; Aguzzi, Adriano (2015). Prion pathogenesis in the absence of NLRP3/ASC inflammasomes. PLoS ONE, 10(2):e0117208.

Aboulenein-Djamshidian, Fahmy; Höftberger, Romana; Waters, Patrick; Krampla, Wolfgang; Lassmann, Hans; Budka, Herbert; Vincent, Angela; Kristoferitsch, Wolfgang (2015). Reduction in serum aquaporin-4 antibody titers during development of a tumor-like brain lesion in a patient with neuromyelitis optica. Journal of Neuropathology and Experimental Neurology, 74(3):194-197.

Rushing, Elisabeth J; Wesseling, Pieter (2015). Towards an integrated morphological and molecular WHO diagnosis of central nervous system tumors. Current Opinion in Neurology, 28(6):628-632.

Zhu, Caihong; Herrmann, Uli S; Li, Bei; Abakumova, Irina; Moos, Rita; Schwarz, Petra; Rushing, Elisabeth J; Colonna, Marco; Aguzzi, Adriano (2015). Triggering receptor expressed on myeloid cells-2 is involved in prion-induced microglial activation but does not contribute to prion pathogenesis in mouse brains. Neurobiology of Aging, 36(5):1994-2003.

Zhu, Caihong; Schwarz, Petra; Abakumova, Irina; Aguzzi, Adriano (2015). Unaltered prion pathogenesis in a mouse model of high-fat diet-induced insulin resistance. PLoS ONE, 10(12):e0144983.

Varsani, Hemlata; Charman, Susan C; Li, Charles K; Marie, Suely K N; Amato, Anthony A; Banwell, Brenda; Bove, Kevin E; Corse, Andrea M; Emslie-Smith, Alison M; Jacques, Thomas S; Lundberg, Ingrid E; Minetti, Carlo; Nennesmo, Inger; Rushing, Elisabeth J; Sallum, Adriana M E; Sewry, Caroline; Pilkington, Clarissa A; Holton, Janice L; Wedderburn, Lucy R (2015). Validation of a score tool for measurement of histological severity in juvenile dermatomyositis and association with clinical severity of disease. Annals of the Rheumatic Diseases, 74(1):204-210.

Scharl, M; Bode, B; Rushing, E; Knuth, A; Rordorf, T (2014). Uncommon case of brain metastasis in a patient with a history of heavy smoking. Current Oncology, 21(5):e728-e731.

Aguzzi, Adriano (2014). Neurodegeneration: Alzheimer's disease under strain. Nature, 512(7512):32-34.

Franklin, Bernardo S; Bossaller, Lukas; De Nardo, Dominic; Ratter, Jacqueline M; Stutz, Andrea; Engels, Gudrun; Brenker, Christoph; Nordhoff, Mark; Mirandola, Sandra R; Al-Amoudi, Ashraf; Mangan, Matthew S; Zimmer, Sebastian; Monks, Brian G; Fricke, Martin; Schmidt, Reinhold E; Espevik, Terje; Jones, Bernadette; Jarnicki, Andrew G; Hansbro, Philip M; Busto, Patricia; Marshak-Rothstein, Ann; Hornemann, Simone; Aguzzi, Adriano; Kastenmüller, Wolfgang; Latz, Eicke (2014). The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation. Nature Immunology, 15(8):727-737.

De Bleecker, Jan L; De Paepe, Boel; Aronica, Eleonora; de Visser, Marianne; Amato, Anthony; Aronica, Eleonora; Benveniste, Olivier; De Bleecker, Jan; de Boer, Onno; De Paepe, Boel; de Visser, Marianne; Dimachkie, Mazen; Gherardi, Romain; Goebel, Hans Hilmar; Hilton-Jones, David; Holton, Janice; Lundberg, Ingrid E; Mammen, Andrew; Mastaglia, Frank; Nishino, Ichizo; Rushing, Elisabeth; Daa Schroder, Henrik; Selcen, Duygu; Stenzel, Werner (2014). 205th ENMC International Workshop: Pathology diagnosis of idiopathic inflammatory myopathies Part II 28–30 March 2014, Naarden, The Netherlands. In: 205th ENMC International Workshop: Pathology diagnosis of idiopathic inflammatory myopathies part II 28-30, Naarden, The Netherlands, 28 March 2014 - 30 March 2014, 268-272.

Hermann, Mario; Stillhard, Patrick; Wildner, Hendrik; Seruggia, Davide; Kapp, Viktor; Sánchez-Iranzo, Héctor; Mercader, Nadia; Montoliu, Lluís; Zeilhofer, Hanns Ulrich; Pelczar, Pawel (2014). Binary recombinase systems for high-resolution conditional mutagenesis. Nucleic Acids Research, 42(6):3894-3907.

Neidert, Marian C; Leske, Henning; Matoscevic, Katja; Eisele, Günter; Rushing, Elisabeth; Sürücü, Oguzkan (2014). A 42-year-old male with a new onset generalized seizure. Brain Pathology, 24(1):99-100.

Dametto, Paolo. Characterization of the flexible tail of the prion protein and its mimic shadoo. 2014, University of Zurich, Faculty of Science.

Tonder, Michaela; Rushing, Elisabeth Jane; Grotzer, Michael; Sürücü, Oguzkan; Valavanis, Antonios; Buck, Alfred; Weller, Michael; Roth, Patrick (2014). Clinical reasoning: a 30-year-old woman with recurrent seizures and a cerebral lesion progressing over 2 decades. Neurology, 82(7):e56-e60.

Akiguchi, Ichiro; Shirakashi, Yoshitomo; Budka, Herbert; Watanabe, Yuko; Watanabe, Toshiyuki; Shiino, Akihiko; Ogita, Mihoko; Kawamoto, Yasuhiro; Jungwirth, Susanne; Krampla, Wolfgang; Fischer, Peter (2014). Disproportionate subarachnoid space hydrocephalus-outcome and perivascular space. Annals of Clinical and Translational Neurology, 1(8):562-569.

Läufer, Thorsten. Estrogen dependent premature lethality due to gut dysfunction in a transgenic TDP-43 mouse model. 2014, University of Zurich, Faculty of Science.

Branscheidt, Meret; Frontzek, Karl; Bozinov, Oliver; Valavanis, Anton; Rushing, Elisabeth J; Weller, Michael; Wegener, Susanne (2014). Etoposide/carboplatin chemotherapy for the treatment of metastatic myxomatous cerebral aneurysms. Journal of Neurology, 261(4):828-830.

Ballmer, Boris. Fluorescence resonance energy transfer assays in prion biology. 2014, University of Zurich, Faculty of Science.

Aguzzi, Adriano; Kranich, Jan; Krautler, Nike Julia (2014). Follicular dendritic cells: origin, phenotype, and function in health and disease. Trends in Immunology, 35(3):105-113.

Smith, Alice Boyd; Horkanyne-Szakaly, Iren; Schroeder, Jason W; Rushing, Elisabeth J (2014). From the radiologic pathology archives: Mass lesions of the dura: beyond meningioma—radiologic-pathologic correlation. Radiographics, 34(2):295-312.

Louis, David N; Perry, Arie; Burger, Peter; Ellison, David W; Reifenberger, Guido; von Deimling, Andreas; Aldape, Kenneth; Brat, Daniel; Collins, V Peter; Eberhart, Charles; Figarella-Branger, Dominique; Fuller, Gregory N; Giangaspero, Felice; Giannini, Caterina; Hawkins, Cynthia; Kleihues, Paul; Korshunov, Andrey; Kros, Johan M; Beatriz Lopes, M; Ng, Ho-Keung; Ohgaki, Hiroko; Paulus, Werner; Pietsch, Torsten; Rosenblum, Marc; Rushing, Elisabeth; Soylemezoglu, Figen; Wiestler, Otmar; Wesseling, Pieter (2014). International Society of Neuropathology-Haarlem Consensus Guidelines for Nervous System Tumor Classification and Grading. Brain Pathology, 24(5):429-435.

Kovacs, Gabor G; Breydo, Leonid; Green, Ryan; Kis, Viktor; Puska, Gina; Lőrincz, Péter; Perju-Dumbrava, Laura; Giera, Regina; Pirker, Walter; Lutz, Mirjam; Lachmann, Ingolf; Budka, Herbert; Uversky, Vladimir N; Molnár, Kinga; László, Lajos (2014). Intracellular processing of disease-associated α-synuclein in the human brain suggests prion-like cell-to-cell spread. Neurobiology of Disease, 69:76-92.

Frontzek, Karl; Fluri, Felix; Siemerkus, Jakob; Müller, Beat; Gass, Achim; Christ-Crain, Mirjam; Katan, Mira (2014). Isolated insular strokes and plasma MR-proANP levels are associated with newly diagnosed atrial fibrillation: A pilot study. PLoS ONE, 9(3):e92421.

Akiguchi, Ichiro; Budka, Herbert; Shirakashi, Yoshitomo; Woehrer, Adelheid; Watanabe, Toshiyuki; Shiino, Akihiko; Yamamoto, Yasumasa; Kawamoto, Yasuhiro; Krampla, Wolfgang; Jungwirth, Susanne; Fischer, Peter (2014). MRI features of Binswanger's disease predict prognosis and associated pathology. Annals of Clinical and Translational Neurology, 1(10):813-821.

Palladini, G; Milani, P; Foli, A; Vidus Rosin, M; Basset, M; Lavatelli, F; Nuvolone, M; Obici, L; Perlini, S; Merlini, G (2014). Melphalan and dexamethasone with or without bortezomib in newly diagnosed AL amyloidosis: A matched case–control study on 174 patients. Leukemia, 28(12):2311-2316.

Hofer, Silvia; Rushing, Elisabeth; Preusser, Matthias; Marosi, Christine (2014). Molecular biology of high grade gliomas: what should the clinician know? Chinese Journal of Cancer, 33(1):4-7.

Rushing, Elisabeth; Kellenberger, Christian; Kana, Veronika; Klein, Andrea (2014). Muscle magnetic resonance imaging of the lower limbs: Valuable diagnostic tool in the investigation of childhood neuromuscular disorders. Neuropediatrics, 45(5):278-288.

Martin, Florence; Kana, Veronika; Mori, Andrea Capone; Fischer, Dirk; Parkin, Nicolas; Boltshauser, Eugen; Rushing, Elisabeth Jane; Klein, Andrea (2014). Neurofibromatosis type 1 (NF1) with an unusually severe phenotype due to digeny for NF1 and ryanodine receptor 1 associated myopathy. European Journal of Pediatrics, 173(12):1691-1694.

Hermann, Mario. Novel techniques for high precision genome engineering. 2014, University of Zurich, Faculty of Science.

Palladini, G; Milani, P; Foli, A; Obici, L; Lavatelli, F; Nuvolone, M; Caccialanza, R; Perlini, S; Merlini, G (2014). Oral melphalan and dexamethasone grants extended survival with minimal toxicity in AL amyloidosis: Long-term results of a risk-adapted approach. Haematologica, 99(4):743-750.

Kurt, Timothy D; Bett, Cyrus; Fernández-Borges, Natalia; Joshi-Barr, Shivanjali; Hornemann, Simone; Rülicke, Thomas; Castilla, Joaquín; Wüthrich, Kurt; Aguzzi, Adriano; Sigurdson, Christina J (2014). Prion transmission prevented by modifying the β2-α2 loop structure of host PrPC. Journal of Neuroscience, 34(3):1022-1027.

Bahi, Amine; Chandrasekar, Vijay; Dreyer, Jean-Luc (2014). Selective lentiviral-mediated suppression of microRNA124a in the hippocampus evokes antidepressants-like effects in rats. Psychoneuroendocrinology, 46:78-87.

Ganzinger, Kristina A; Narayan, Priyanka; Qamar, Seema S; Weimann, Laura; Ranasinghe, Rohan T; Aguzzi, Adriano; Dobson, Christopher M; McColl, James; et al (2014). Single-molecule imaging reveals that small Amyloid-β1-42Oligomers interact with the Cellular Prion Protein (PrPC). Chembiochem, 15(17):2515-2521.

Baral, Pravas Kumar; Swayampakula, Mridula; Rout, Manoj Kumar; Kav, Nat N V; Spyracopoulos, Leo; Aguzzi, Adriano; James, Michael N G (2014). Structural basis of prion inhibition by phenothiazine compounds. Structure, 22(2):291-303.

Kusne, Y; Carrera-Silva, E A; Perry, A S; Rushing, E J; Mandell, E K; Dietrich, J D; Errasti, A E; Gibbs, D; Berens, M E; Loftus, J C; Hulme, C; Yang, W; Lu, Z; Aldape, K; Sanai, N; Rothlin, C V; Ghosh, S (2014). Targeting aPKC disables oncogenic signaling by both the EGFR and the proinflammatory cytokine TNF in glioblastoma. Science Signaling, 7(338):ra75.

Yaldizli, Ozgür; Penner, Iris-Katharina; Frontzek, Karl; Naegelin, Yvonne; Amann, Michael; Papadopoulou, Athina; Sprenger, Till; Kuhle, Jens; Calabrese, Pasquale; Radü, Ernst Wilhelm; Kappos, Ludwig; Gass, Achim (2014). The relationship between total and regional corpus callosum atrophy, cognitive impairment and fatigue in multiple sclerosis patients. Multiple Sclerosis, 20(3):356-364.

Sorce, Silvia; Nuvolone, Mario; Keller, Annika; Falsig, Jeppe; Varol, Ahmet; Schwarz, Petra; Bieri, Monika; Budka, Herbert; Aguzzi, Adriano (2014). The role of the NADPH oxidase NOX2 in prion pathogenesis. PLoS Pathogens, 10(12):e1004531.

Scaravilli, Francesco; Hale, Martin; Budka, Herbert (2013). ISN Information Days at the University of Witwatersrand Medical School, Johannesburg (South Africa) on September 23(rd) -24(th) , 2013. In: Fourth Information Days on Neuropathology, Johannesburg, 23 September 2013 - 24 September 2013, i-ii.

Rushing, Elisabeth J (2013). Muscle Involvement in Connective Tissue Disorders: Polyarteritis, Rheumatoid Arthritis, Systemic Lupus Erythematosus, Systemic Sclerosis, and Sjögren Syndrome. In: Goebel, Hans H; Sewry, Caroline A; Weller, Roy O. Muscle Disease: Pathology and Genetics. New York: Wiley-Blackwell, 313-315.

Foit, N A; Neidert, M C; Woernle, C M; Rushing, Elisabeth J; Krayenbühl, N (2013). Bifocal extra- and intradural melanocytoma of the spine: case report and literature review. European Spine Journal, 22(Suppl 3):521-525.

Zeilhofer, Ulrike B; Scheer, Ianina; Warmuth-Metz, Monika; Rushing, Elisabeth J; Pietsch, Torsten; Boltshauser, Eugen; Grotzer, Michael A; Gerber, Nicolas U (2013). Natural history of a medulloblastoma: 30 months of wait and see in a child with a cerebellar incidentaloma. Child's Nervous System, 29(7):1207-1210.

Budka, Herbert (2013). Neuropathology. In: Runehov, Anne; Oviedo, Lluis. Encyclopedia of Sciences and Religions. Dordrecht: Springer, 777.

Budka, H; Kovacs, G G (2013). Gerstmann–Sträussler–Scheinker Disease. In: Maloy, Stanley; Hughes, Kelly. Brenner's Encyclopedia of Genetics, 2nd Edition. New York: Elsevier B.V., 327-329.

Magagna-Poveda, Alejandra; Frontzek, Karl; Bode-Lesniewska, Beata; Rushing, Elisabeth J (2013). A 59-year-old woman with a retroauricular tumor. Brain Pathology, 23(5):603-604.

Wernhart, S; Woernle, C M; Neidert, M C; Bode, B; Rushing, E J; Studer, G; Fuchs, I; Regli, L; Sürücü, O (2013). A deeply seated brain metastasis from a primary myxofibrosarcoma: Case report. Clinical Neurology and Neurosurgery, 115(10):2296-2298.

Aguzzi, Adriano; Gitler, Aaron D (2013). A template for new drugs against Alzheimer's Disease. Cell, 154(6):1182-1184.

Hütt-Cabezas, Marianne; Karajannis, Matthias A; Zagzag, David; Shah, Smit; Horkayne-Szakaly, Iren; Rushing, Elisabeth J; Cameron, J Douglas; Jain, Deepali; Eberhart, Charles G; Raabe, Eric H; Rodriguez, Fausto J (2013). Activation of mTORC1/mTORC2 signaling in pediatric low-grade glioma and pilocytic astrocytoma reveals mTOR as a therapeutic target. Neuro-Oncology, 15(12):1604-1614.

Margalith, Ilan. Anti-prion effect of polythiophenes. 2013, University of Zurich, Faculty of Science.

Krasemann, Susanne; Mearini, Giulia; Krämer, Elisabeth; Wagenführ, Katja; Schulz-Schaeffer, Walter; Neumann, Melanie; Bodemer, Walter; Kaup, Franz-Josef; Beekes, Michael; Carrier, Lucie; Aguzzi, Adriano; Glatzel, Markus (2013). BSE-associated prion-amyloid cardiomyopathy in primates. Emerging Infectious Diseases, 19(6):985-988.

Bellut, D; Holzmann, D; de Alba Buenrostro, G; Rushing, E J; Bernays, R L (2013). CSF containing cystic lesion of the clivus-case report and review of the literature. Clinical Neurology and Neurosurgery, 115(1):95-98.

Ehling, Rainer; Nosková, Lenka; Stránecký, Viktor; Hartmannová, Hana; Přistoupilová, Anna; Hodaňová, Kateřina; Benke, Thomas; Kovacs, Gabor G; Ströbel, Thomas; Niedermüller, Ulrike; Wagner, Michaela; Nachbauer, Wolfgang; Janecke, Andreas; Budka, Herbert; Boesch, Sylvia; Kmoch, Stanislav (2013). Cerebellar dysfunction in a family harboring the PSEN1 mutation co-segregating with a Cathepsin D variant p.A58V. Journal of the Neurological Sciences, 326(1-2):75-82.

Manoli, Irini; Kwan, Justin Y; Wang, Qian; Rushing, Elisabeth J; Tsokos, Maria; Arai, Andrew E; Burch, Warner M; Dispenzieri, Angela; McPherron, Alexandra C; Gahl, William A (2013). Chronic myopathy due to immunoglobulin light chain amyloidosis. Molecular Genetics and Metabolism, 108(4):249-254.

Sanchez-Macedo, N; Feng, J; Faubert, B; Chang, N; Elia, A; Rushing, E J; Tsuchihara, K; Bungard, D; Berger, S L; Jones, R G; Mak, T W; Zaugg, K (2013). Depletion of the novel p53-target gene carnitine palmitoyltransferase 1C delays tumor growth in the neurofibromatosis type I tumor model. Cell Death and Differentiation, 20(4):659-668.

Sponarova, Jana; Nuvolone, Mario; Whicher, Charlotte; Frei, Nathalie; Kana, Veronika; Schwarz, Petra; Westermark, Gunilla T; Aguzzi, Adriano (2013). Efficient amyloid a clearance in the absence of immunoglobulins and complement factors. American Journal of Pathology, 182(4):1297-1307.

Wanschitz, Julia V; Dubourg, Odile; Lacene, Emmanuelle; Fischer, Michael B; Höftberger, Romana; Budka, Herbert; Romero, Norma B; Eymard, Bruno; Herson, Serge; Butler-Browne, Gillian S; Voit, Thomas; Benveniste, Olivier (2013). Expression of myogenic regulatory factors and myo-endothelial remodeling in sporadic inclusion body myositis. Neuromuscular Disorders : NMD, 23(1):75-83.

Magagna-Poveda, A; Leske, H; Schmid, C; Bernays, R; Rushing, E (2013). Expression of somatostatin receptors, angiogenesis and proliferation markers in pituitary adenomas: an immunohistochemical study with diagnostic and therapeutic implications. Swiss Medical Weekly, 143:w13895.

Deuster, Patricia A; Contreras-Sesvold, Carmen L; O'Connor, Francis G; Campbell, William W; Kenney, Kimbra; Capacchione, John F; Landau, Mark E; Muldoon, Sheila M; Rushing, Elisabeth J; Heled, Yuval (2013). Genetic polymorphisms associated with exertional rhabdomyolysis. European Journal of Applied Physiology, 113(8):1997-2004.

Ahmed, Zeshan; Bigio, Eileen H; Budka, Herbert; Dickson, Dennis W; Ferrer, Isidro; Ghetti, Bernardino; Giaccone, Giorgio; Hatanpaa, Kimmo J; Holton, Janice L; Josephs, Keith A; Powers, James; Spina, Salvatore; Takahashi, Hitoshi; White, Charles L; Revesz, Tamas; Kovacs, Gabor G (2013). Globular glial tauopathies (GGT): consensus recommendations. Acta Neuropathologica, 126(4):537-544.

Deubelbeiss, A N; Trachsel, C; Bachli, E B; Kuffer, A; Budka, H; Eniseyskiy, P; Zimmermann, H; Wallace, R M; Farley, S; Zanoni, R G (2013). Imported human rabies in Switzerland, 2012: a diagnostic conundrum. Journal of Clinical Virology, 57(2):178-181.

Klug, Genevieve M J A; Wand, Handan; Simpson, Marion; Boyd, Alison; Law, Matthew; Masters, Colin L; Matej, Radoslav; Howley, Rachel; Farrell, Michael; Breithaupt, Maren; Zerr, Inga; van Duijn, Cornelia; Ibrahim-Verbaas, Carla; Mackenzie, Jan; Will, Robert G; Brandel, Jean-Philippe; Alperovitch, Annick; Budka, Herbert; Kovacs, Gabor G; Jansen, Gerard H; Coulthard, Michael; Collins, Steven J (2013). Intensity of human prion disease surveillance predicts observed disease incidence. Journal of Neurology, Neurosurgery, and Psychiatry, 84(12):1372-1377.

Schippling, S; Kempf, C; Büchele, F; Jelcic, I; Bozinov, O; Bont, A; Linnebank, M; Sospedra, M; Weller, M; Budka, H; Martin, R (2013). JCV granule cell neuronopathy and GCN-IRIS under natalizumab treatment. Annals of Neurology, 74(4):622-626.

Aguzzi, Adriano; Barres, Ben A; Bennett, Mariko L (2013). Microglia: scapegoat, saboteur, or something else? Science, 339(6116):156-161.

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Neumann, M; Rademakers, R; Roeber, S; Baker, M; Kretzschmar, H A; Mackenzie, I R A (2009). A new subtype of frontotemporal lobar degeneration with FUS pathology. Brain: A Journal of Neurology, 132(Pt 11):2922-2931.

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Oliveira-Martins, J B. Alpha-cleavage of the prion protein and the putative function of the prion protein in lymphocyte homeostasis. 2009, University of Zurich, Faculty of Science.

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Aguzzi, A (2009). Cell biology: Beyond the prion principle. Nature, 459(7249):924-925.

Nuvolone, M; Aguzzi, A; Heikenwalder, M (2009). Cells and prions: A license to replicate. FEBS Letters, 583(16):2674-2684 .

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Igaz, L M; Kwong, L K; Chen-Plotkin, A; Winton, M J; Unger, T L; Xu, Y; Neumann, M; Trojanowski, J Q; Lee, V M Y (2009). Expression of TDP-43 C-terminal fragments in vitro recapitulates pathological features of TDP-43 proteinopathies. Journal of Biological Chemistry, 284(13):8516-8524.

Munoz, D G; Neumann, M; Kusaka, H; Yokota, O; Ishihara, K; Terada, S; Kuroda, S; Mackenzie, I R A (2009). FUS pathology in basophilic inclusion body disease. Acta Neuropathologica, 118(5):617-627.

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Danek, A; Diehl-Schmid, J; Grimmer, T; Laws, S M; Neumann, M; Perneczky, R; Riemenschneider, M; Kurz, A; Förstl, H (2009). Frontotemporale Lobärdegenerationen. Teil 1: Diagnose und Therapie. Fortschritte der Neurologie, Psychiatrie, 77(3):169-176; quiz 177-179.

Diehl-Schmid, J; Neumann, M; Laws, S M; Perneczky, R; Grimmer, T; Danek, A; Kurz, A; Riemenschneider, M; Förstl, H (2009). Frontotemporale Lobärdegenerationen. Teil 2: Bildgebung, Neuropathologie und Genetik. Fortschritte der Neurologie, Psychiatrie, 77(5):295-304.

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Ingold, B; Schraml, P; Heppner, F L; Moch, H (2009). Homogeneous MGMT immunoreactivity correlates with an unmethylated MGMT promoter status in brain metastases of various solid tumors. PLoS ONE, 4(3):e4775.

Nazabal, A; Hornemann, S; Aguzzi, A; Zenobi, R (2009). Hydrogen/deuterium exchange mass spectrometry identifies two highly protected regions in recombinant full-length prion protein amyloid fibrils. Journal of Mass Spectrometry, 44(6):965-977.

Eisele, Y S; Bolmont, T; Heikenwalder, M; Langer, F; Jacobson, L H; Yan, Z X; Roth, K; Aguzzi, A; Staufenbiel, M; Walker, L C; Jucker, M (2009). Induction of cerebral beta-amyloidosis: intracerebral versus systemic Abeta inoculation. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 106(31):12926-12931.

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Schell, H; Hasegawa, T; Neumann, M; Kahle, P J (2009). Nuclear and neuritic distribution of serine-129 phosphorylated alpha-synuclein in transgenic mice. Neuroscience, 160(4):796-804.

Neumann, M; Kwong, L K; Lee, E B; Kremmer, E; Flatley, A; Xu, Y; Forman, M S; Troost, D; Kretzschmar, H A; Trojanowski, J Q; Lee, V M Y (2009). Phosphorylation of S409/410 of TDP-43 is a consistent feature in all sporadic and familial forms of TDP-43 proteinopathies. Acta Neuropathologica, 117(2):137-149.

Christen, B; Hornemann, S; Damberger, F F; Wüthrich, K (2009). Prion protein NMR structure from tammar wallaby (Macropus eugenii) shows that the β2–α2 loop is modulated by long-range sequence effects. Journal of Molecular Biology, 389(5):833-845.

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Race, B; Meade-White, K; Race, R; Baumann, F; Aguzzi, A; Chesebro, B (2009). Prion protein on astrocytes or in extracellular fluid impedes neurodegeneration induced by truncated prion protein. Experimental Neurology, 217(2):347-352.

Hornemann, S; von Schroetter, C; Damberger, F F; Wüthrich, K (2009). Prion protein-detergent micelle interactions studied by NMR in solution. Journal of Biological Chemistry, 284(34):22713-22721.

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Aguzzi, A; Calella, A M (2009). Prions: protein aggregation and infectious diseases. Physiological Reviews, 89(4):1105-1152.

Dormann, D; Capell, A; Carlson, A M; Shankaran, S S; Rodde, R; Neumann, M; Kremmer, E; Matsuwaki, T; Yamanouchi, K; Nishihara, M; Haass, C (2009). Proteolytic processing of TAR DNA binding protein-43 by caspases produces C-terminal fragments with disease defining properties independent of progranulin. Journal of Neurochemistry, 110(3):1082-1094.

Fuchs, T J; Haybaeck, J; Wild, P J; Heikenwalder, M; Moch, H; Aguzzi, A; Buhmann, J M (2009). Randomized tree ensembles for object detection in computational pathology. In: Bebis, G; et al. Advances in Visual Computing : 5th International Symposium, ISVC 2009, Las Vegas, NV, USA, November 30 - December 2, 2009, Proceedings, Part 1. Berlin: Springer, 367-380.

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Rutishauser, D; Mertz, K D; Moos, R; Brunner, E; Rülicke, T; Calella, A M; Aguzzi, A (2009). The comprehensive native interactome of a fully functional tagged prion protein. PLoS ONE, 4(2):e4446.

Aguzzi, A; Rajendran, L (2009). The transcellular spread of cytosolic amyloids, prions, and prionoids. Neuron, 64(6):783-790.

Lippa, C F; Rosso, A L; Stutzbach, L D; Neumann, M; Lee, V M Y; Trojanowski, J Q (2009). Transactive response DNA-binding protein 43 burden in familial Alzheimer disease and Down syndrome. Archives of Neurology, 66(12):1483-1488.

Bridel, C. Transgenic expression of the amino-terminus of the prion protein and assessment of the nasal cavity as an entry site for prions. 2009, University of Zurich, Faculty of Science.

Baenziger, S; Heikenwalder, M; Johansen, P; Schlaepfer, E; Hofer, U; Miller, R; Diemand, S; Honda, K; Kundig, T M; Aguzzi, A; Speck, R F (2009). Triggering TLR7 in mice induces immune activation and lymphoid system disruption, resembling HIV-mediated pathology. Blood, 113(2):377-388.

Miele, G; Seeger, H; Marino, D; Eberhard, R; Heikenwalder, M; Stoeck, K; Basagni, M; Knight, R; Green, A; Chianini, F; Wüthrich, R P; Hock, C; Zerr, I; Aguzzi, A (2008). Urinary alpha1-antichymotrypsin: a biomarker of prion infection. PLoS ONE, 3(12):e3870.

Seeger, H; Julius, C; Cozzari, C; Calella, A M; Dattilo, M; Aguzzi, A (2008). Prion depletion and preservation of biological activity by preparative chaotrope ultracentrifugation. Biologicals, 36(6):403-411.

Ott, D; Taraborrelli, C; Aguzzi, A (2008). Novel dominant-negative prion protein mutants identified from a randomized library. Protein Engineering Design and Selection : PEDS, 21(10):623-629.

Steele, A D; Hutter, G; Jackson, W S; Heppner, F L; Borkowski, A W; King, O D; Raymond, G J; Aguzzi, A; Lindquist, S (2008). Heat shock factor 1 regulates lifespan as distinct from disease onset in prion disease. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 105(36):13626-13631.

Chen, D; Steele, A D; Hutter, G; Bruno, J; Govindarajan, A; Easlon, E; Lin, S J; Aguzzi, A; Lindquist, S; Guarente, L (2008). The role of calorie restriction and SIRT1 in prion-mediated neurodegeneration. Experimental Gerontology, 43(12):1086-1093.

Kranich, J; Krautler, N J; Heinen, E; Polymenidou, M; Bridel, C; Schildknecht, A; Huber, C; Kosco-Vilbois, M H; Zinkernagel, R; Miele, G; Aguzzi, A (2008). Follicular dendritic cells control engulfment of apoptotic bodies by secreting Mfge8. Journal of Experimental Medicine, 205(6):1293-1302.

Heikenwalder, M; Prinz, M; Zeller, N; Lang, K S; Junt, T; Rossi, S; Tumanov, A; Schmidt, H; Priller, J; Flatz, L; Rülicke, T; Macpherson, A J; Holländer, G A; Nedospasov, S A; Aguzzi, A (2008). Overexpression of lymphotoxin in T cells induces fulminant thymic involution. American Journal of Pathology, 172(6):1555-1570.

von Poser-Klein, C; Flechsig, E; Hoffmann, T; Schwarz, P; Harms, H; Bujdoso, R; Aguzzi, A; Klein, M A (2008). Alteration of B-cell subsets enhances neuroinvasion in mouse scrapie infection. Journal of Virology, 82(7):3791-3795.

Debatin, L; Streffer, J; Geissen, M; Matschke, J; Aguzzi, A; Glatzel, M (2008). Association between deposition of beta-amyloid and pathological prion protein in sporadic Creutzfeldt-Jakob disease. Neurodegenerative Diseases, 5(6):347-354.

Falsig, J; Julius, C; Margalith, I; Schwarz, P; Heppner, F L; Aguzzi, A (2008). A versatile prion replication assay in organotypic brain slices. Nature Neuroscience, 11(1):109-117.

Genoud, N; Ott, D; Braun, N; Prinz, M; Schwarz, P; Suter, U; Trono, D; Aguzzi, A (2008). Antiprion prophylaxis by gene transfer of a soluble prion antagonist. American Journal of Pathology, 172(5):1287-1296.

Polymenidou, M; Trusheim, H; Stallmach, L; Moos, R; Julius, C; Miele, G; Lenz-Bauer, C; Aguzzi, A (2008). Canine MDCK cell lines are refractory to infection with human and mouse prions. Vaccine, 26(21):2601-2614.

Falsig, J; Nilsson, K P R; Knowles, T P J; Aguzzi, A (2008). Chemical and biophysical insights into the propagation of prion strains. HFSP Journal, 2(6):332-341.

Haybaeck, J; Silye, R; Soffer, D (2008). Dural arachnoid granulations and "giant" arachnoid granulations. Surgical and Radiologic Anatomy, 30(5):417-421.

Hutter, G. Establishing a Humanized Mouse Model to Study Prions. 2008, University of Zurich, Faculty of Science.

Weis, S; Haybaeck, J; Dulay, J R; Llenos, I C (2008). Expression of cellular prion protein (PrP(c)) in schizophrenia, bipolar disorder, and depression. Journal of Neural Transmission, 115(5):761-771.

Gavín, R; Ureña, J M; Rangel, A; Pastrana, M A; Requena, J R; Soriano, E; Aguzzi, A; Del Río, J A (2008). Fibrillar prion peptide PrP(106-126) treatment induces Dab1 phosphorylation and impairs APP processing and A beta production in cortical neurons. Neurobiology of Disease, 30(2):243-254.

Stoeck, K; Hess, K; Amsler, L; Eckert, T; Zimmermann, D R; Aguzzi, A; Glatzel, M (2008). Heightened incidence of sporadic Creutzfeldt-Jakob disease is associated with a shift in clinicopathological profiles. Journal of Neurology, 255(10):1464-1472.

Brunhuber, T; Haybaeck, J; Schäfer, G; Mikuz, G; Langhoff, E; Saeland, S; Lebecque, S; Romani, N; Obrist, P (2008). Immunohistochemical tracking of an immune response in mammary Paget's disease. Cancer Letters, 272(2):206-220.

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Aguzzi, A; Sigurdson, C; Heikenwaelder, M (2008). Molecular mechanisms of prion pathogenesis. Annual Review of Pathology, 3:11-40.

Martinez Gomez, J M. Novel treatments in allergen-specific immunotherapy. 2008, University of Zurich, Faculty of Science.

Le Pichon, C E; Valley, M T; Polymenidou, M; Chesler, A T; Sagdullaev, B T; Aguzzi, A; Firestein, S (2008). Olfactory behavior and physiology are disrupted in prion protein knockout mice. Nature Neuroscience, 12(1):60-69.

Harrer, M D. Organotypic CNS Slice Cultures as an in vitro Model for Damage and Repair in Multiple Sclerosis. 2008, University of Zurich, Faculty of Science.

Falsig Pedersen, J. Prion Disease in Brain Slice Cultures. 2008, University of Zurich, Faculty of Science.

Kranich, J. Prion Replication, Phagocytosis, and the Function of Follicular Dendritic Cells. 2008, University of Zurich, Faculty of Science.

Julius, C; Heikenwalder, M; Schwarz, P; Marcel, A; Karin, M; Prinz, M; Pasparakis, M; Aguzzi, A (2008). Prion propagation in mice lacking central nervous system NF-kappaB signalling. Journal of General Virology, 89(6):1545-1550.

Ingold, B; Wild, P J; Nocito, A; Amin, M B; Storz, M; Heppner, F L; Moch, H (2008). Renal cell carcinoma marker reliably discriminates central nervous system haemangioblastoma from brain metastases of renal cell carcinoma. Histopathology, 52(6):674-681.

Mittelbronn, M; Capper, D; Bader, B; Schittenhelm, J; Haybaeck, J; Weber, P; Meyermann, R; Kretzschmar, H A; Wietholter, H (2008). Severe hypoxia and multiple infarctions resembling Creutzfeldt-Jakob disease. Folia Neuropathologica, 46(2):149-153.

Aguzzi, A (2008). Staining, straining and restraining prions. Nature Neuroscience, 11(11):1239-1240.

Sumara, G. The MAPK p38δ regulate glucose homeostasis by suppressing insulin secretion from pancreatic β cells. 2008, University of Zurich, Faculty of Science.

Polymenidou, M; Moos, R; Scott, M; Sigurdson, C; Shi, Y Z; Yajima, B; Hafner-Bratkovic, I; Jerala, R; Hornemann, S; Wuthrich, K; Bellon, A; Vey, M; Garen, G; James, M N G; Kav, N; Aguzzi, A (2008). The POM monoclonals: a comprehensive set of antibodies to non-overlapping prion protein epitopes. PLoS ONE, 3(12):e3872.

Falsig, J; Aguzzi, A (2008). The prion organotypic slice culture assay-POSCA. Nature Protocols, 3(4):555-562.

Aguzzi, A; Baumann, F; Bremer, J (2008). The prion's elusive reason for being. Annual Review of Neuroscience, 31:439-477.

Julius, C; Hutter, G; Wagner, U; Seeger, H; Kana, V; Kranich, J; Klöhn, P C; Weissmann, C; Miele, G; Aguzzi, A (2008). Transcriptional stability of cultured cells upon prion infection. Journal of Molecular Biology, 375(5):1222-1233.

Aguzzi, A (2008). Unraveling prion strains with cell biology and organic chemistry. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 105(1):11-12.

Aguzzi, A (2007). Prion biology: the quest for the test. Nature Methods, 4(8):614-616.

Sigurdson, C J; Aguzzi, A (2007). Chronic wasting disease. Biochimica et Biophysica Acta, 1772(6):610-618.

Steele, A D; Lindquist, S; Aguzzi, A (2007). The prion protein knockout mouse: a phenotype under challenge. Prion, 1(2):83-93.

Nicolas, O; Gavín, R; Braun, N; Ureña, J M; Fontana, X; Soriano, E; Aguzzi, A; del Río, J A (2007). Bcl-2 overexpression delays caspase-3 activation and rescues cerebellar degeneration in prion-deficient mice that overexpress amino-terminally truncated prion. FASEB Journal, 21(12):3107-3117.

Marruchella, G; Ligios, C; Albanese, V; Cancedda, M G; Madau, L; Lalatta-Costerbosa, G; Mazzoni, M; Clavenzani, P; Chiocchetti, R; Sarli, G; De Grossi, L; Agrimi, U; Aguzzi, A; Di Guardo, G (2007). Enteroglial and neuronal involvement without apparent neuron loss in ileal enteric nervous system plexuses from scrapie-affected sheep. Journal of General Virology, 88(Pt 10):2899-2904.

Heikenwalder, Mathias; Federau, Christian; Boehmer, Lotta von; Schwarz, Petra; Wagner, Mareike; Zeller, Nicolas; Haybaeck, Johannes; Prinz, Marco; Becher, Burkhard; Aguzzi, Adriano (2007). Germinal center B cells are dispensable in prion transport and neuroinvasion. Journal of Neuroimmunology, 192(1-2):113-123.

Aguzzi, A; Heikenwalder, M; Polymenidou, M (2007). Insights into prion strains and neurotoxicity. Nature Reviews. Molecular Cell Biology, 8(7):552-561.

Baumann, F; Tolnay, M; Brabeck, C; Pahnke, J; Kloz, U; Niemann, H H; Heikenwalder, M; Rülicke, T; Bürkle, A; Aguzzi, A (2007). Lethal recessive myelin toxicity of prion protein lacking its central domain. EMBO Journal, 26(2):538-547.

Sigurdson, Christina J; Nilsson, K Peter R; Hornemann, Simone; Manco, Giuseppe; Polymenidou, Magdalini; Schwarz, Petra; Leclerc, Mario; Hammarström, Per; Wüthrich, Kurt; Aguzzi, Adriano (2007). Prion strain discrimination using luminescent conjugated polymers. Nature Methods, 4(12):1023-1030.

Heikenwalder, M; Julius, C; Aguzzi, A (2007). Prions and peripheral nerves: a deadly rendezvous. Journal of Neuroscience Research, 85(12):2714-2725.

Zabel, M D; Heikenwalder, M; Prinz, M; Arrighi, I; Schwarz, P; Kranich, J; von Teichman, A; Haas, K M; Zeller, N; Tedder, T F; Weis, J H; Aguzzi, A (2007). Stromal complement receptor CD21/35 facilitates lymphoid prion colonization and pathogenesis. Journal of Immunology, 179(9):6144-6152.

Sigurdson, C J; Manco, G J; Schwarz, P; Liberski, P; Hoover, E A; Hornemann, S; Polymenidou, M; Miller, M W; Glatzel, M; Aguzzi, A (2006). Strain fidelity of chronic wasting disease upon murine adaptation. Journal of Virology, 80(24):12303-12311.

Junt, T; Tumanov, A V; Harris, N; Heikenwalder, M; Zeller, N; Kuprash, D V; Aguzzi, A; Ludewig, B; Nedospasov, S A; Zinkernagel, R M (2006). Expression of lymphotoxin beta governs immunity at two distinct levels. European Journal of Immunology, 36(8):2061-2075.

Aguzzi, A (2006). Prion diseases of humans and farm animals: epidemiology, genetics, and pathogenesis. Journal of Neurochemistry, 97(6):1726-1739.

Landolt, H P; Glatzel, M; Blättler, T; Achermann, P; Roth, C; Mathis, J; Weis, J; Tobler, I; Aguzzi, A; Bassetti, C L (2006). Sleep-wake disturbances in sporadic Creutzfeldt-Jakob disease. Neurology, 66(9):1418-1424.

Vogelgesang, S; Glatzel, M; Walker, L C; Kroemer, H K; Aguzzi, A; Warzok, R W (2006). Cerebrovascular P-glycoprotein expression is decreased in Creutzfeldt-Jakob disease. Acta Neuropathologica, 111(5):436-443.

Schoch, G; Seeger, H; Bogousslavsky, J; Tolnay, M; Janzer, R C; Aguzzi, A; Glatzel, M (2006). Analysis of prion strains by PrPSc profiling in sporadic Creutzfeldt-Jakob disease. PLoS Medicine, 3(2):e14.

Baenziger, S; Tussiwand, R; Schlaepfer, E; Mazzucchelli, L; Heikenwalder, M; Kurrer, M O; Behnke, S; Frey, J; Oxenius, A; Joller, H; Aguzzi, A; Manz, M G; Speck, R F (2006). Disseminated and sustained HIV infection in CD34+ cord blood cell-transplanted Rag2-/-gamma c-/- mice. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 103(43):15951-15956.

Priller, J; Prinz, M; Heikenwalder, M J; Zeller, N; Schwarz, P; Heppner, F L; Aguzzi, A (2006). Early and rapid engraftment of bone marrow-derived microglia in scrapie. Journal of Neuroscience, 26(45):11753-11762.

Aguzzi, A; Heikenwalder, M (2006). Pathogenesis of prion diseases: current status and future outlook. Nature Reviews. Microbiology, 4(10):765-775.

Aguzzi, A; Glatzel, M (2006). Prion infections, blood and transfusions. Nature Reviews. Neurology, 2(6):321-329.

Polymenidou, M; Stoeck, K; Glatzel, M; Vey, M; Bellon, A; Aguzzi, A (2005). Coexistence of multiple PrPSc types in individuals with Creutzfeldt-Jakob disease. Lancet Neurology, 4(12):805-814.

Kovács, G G; et al; Aguzzi, A (2005). Genetic prion disease: the EUROCJD experience. Human Genetics, 118(2):166-174.

Galvan, C; Camoletto, P G; Dotti, C G; Aguzzi, A; Ledesma, M D (2005). Proper axonal distribution of PrP(C) depends on cholesterol-sphingomyelin-enriched membrane domains and is developmentally regulated in hippocampal neurons. Molecular and Cellular Neuroscience, 30(3):304-315.

Seeger, Harald; Heikenwalder, Mathias; Zeller, Nicolas; Kranich, Jan; Schwarz, Petra; Gaspert, Ariana; Seifert, Burkhardt; Miele, Gino; Aguzzi, Adriano (2005). Coincident scrapie infection and nephritis lead to urinary prion excretion. Science, 310(5746):324-326.

Gavín, R; Braun, N; Nicolas, O; Parra, B; Ureña, J M; Mingorance, A; Soriano, E; Torres, J M; Aguzzi, A; del Río, J A (2005). PrP(106-126) activates neuronal intracellular kinases and Egr1 synthesis through activation of NADPH-oxidase independently of PrPc. FEBS Letters, 579(19):4099-4106.

Papassotiropoulos, A; Wollmer, M A; Aguzzi, A; Hock, Christoph; Nitsch, R M; de Quervain, D J F (2005). The prion gene is associated with human long-term memory. Human Molecular Genetics, 14(15):2241-2246.

Donofrio, G; Heppner, F L; Polymenidou, M; Musahl, C; Aguzzi, A (2005). Paracrine inhibition of prion propagation by anti-PrP single-chain Fv miniantibodies. Journal of Virology, 79(13):8330-8338.

Glatzel, M; Mohajeri, M H; Poirier, R; Nitsch, R M; Schwarz, Petra; Lu, B; Aguzzi, A (2005). No influence of amyloid-beta-degrading neprilysin activity on prion pathogenesis. Journal of General Virology, 8(6):1861-1867.

Radovanovic, I; Braun, N; Giger, O T; Mertz, K; Miele, G; Prinz, M; Navarro, B; Aguzzi, A (2005). Truncated prion protein and Doppel are myelinotoxic in the absence of oligodendrocytic PrPC. Journal of Neuroscience, 25(19):4879-4888.

Ladogana, A; Puopolo, M; Croes, E A; Budka, H; Jarius, C; Collins, S; Klug, G M; Sutcliffe, T; Giulivi, A; Alperovitch, A; Delasnerie-Laupretre, N; Brandel, J-P; Poser, S; Kretzschmar, H A; Rietveld, I; Mitrova, E; Cuesta, J de Pedro; Martinez-Martin, P; Glatzel, M; Aguzzi, A; Knight, R; Ward, H; Pocchiari, M; van Duijn, C M; Will, R G; Zerr, I (2005). Mortality from Creutzfeldt-Jakob disease and related disorders in Europe, Australia, and Canada. Neurology, 64(9):1586-1591.

Frappart, P O; Tong, W M; Demuth, I; Radovanovic, I; Herceg, Z; Aguzzi, A; Digweed, M; Wang, Z Q (2005). An essential function for NBS1 in the prevention of ataxia and cerebellar defects. Nature Medicine, 11(5):538-544.

Huber, C; Thielen, C; Seeger, H; Schwarz, Petra; Montrasio, F; Wilson, M R; Heinen, E; Fu, Yang-Xin; Miele, G; Aguzzi, A (2005). Lymphotoxin-beta receptor-dependent genes in lymph node and follicular dendritic cell transcriptomes. Journal of Immunology, 174(9):5526-5536.

Nikles, D; Bach, P; Boller, K; Merten, C A; Montrasio, F; Heppner, F L; Aguzzi, A; Cichutek, K; Kalinke, U; Buchholz, C J (2005). Circumventing tolerance to the prion protein (PrP): vaccination with PrP-displaying retrovirus particles induces humoral immune responses against the native form of cellular PrP. Journal of Virology, 79(7):4033-4042.

Glatzel, M; Stoeck, K; Seeger, H; Lührs, T; Aguzzi, A (2005). Human prion diseases: molecular and clinical aspects. Archives of Neurology, 62(4):545-552.

Russmann, H; Vingerhoets, F; Miklossy, J; Maeder, P; Glatzel, M; Aguzzi, A; Bogousslavsky, J (2005). Sporadic Creutzfeldt-Jakob disease: a comparison of pathological findings and diffusion weighted imaging. Journal of Neurology, 252(3):338-342.

Uelhoff, A; Tatzelt, J; Aguzzi, A; Winklhofer, K F; Haass, C (2005). A pathogenic PrP mutation and doppel interfere with polarized sorting of the prion protein. Journal of Biological Chemistry, 280(7):5137-5140.

Heikenwalder, M; Zeller, N; Seeger, H; Prinz, M; Klöhn, P C; Schwarz, Petra; Ruddle, N H; Weissmann, Charles; Aguzzi, A (2005). Chronic lymphocytic inflammation specifies the organ tropism of prions. Science, 307(5712):1107-1110.

Masel, J; Genoud, Nicolas; Aguzzi, A (2005). Efficient inhibition of prion replication by PrP-Fc(2) suggests that the prion is a PrP(Sc) oligomer. Journal of Molecular Biology, 345(5):1243-1251.

Heppner, F L; Greter, M; Marino, D; Falsig, J; Raivich, G; Hövelmeyer, N; Waisman, A; Rülicke, T; Prinz, M; Priller, J; Becher, B; Aguzzi, A (2005). Experimental autoimmune encephalomyelitis repressed by microglial paralysis. Nature Medicine, 11(2):146-152.

Steinacker, P; Schwarz, P; Reim, K; Brechlin, P; Jahn, O; Kratzin, H; Aitken, A; Wiltfang, J; Aguzzi, A; Bahn, E; Baxter, H C; Brose, Nils; Otto, M (2005). Unchanged survival rates of 14-3-3gamma knockout mice after inoculation with pathological prion protein. Molecular and Cellular Biology, 25(4):1339-1346.

Weissmann, Charles; Aguzzi, A (2005). Approaches to therapy of prion diseases. Annual Review of Medicine, 56:321-344.

Aguzzi, A (2005). Cell biology. Prion toxicity: all sail and no anchor. Science, 308(5727):1420-1421.

Sigurdson, C A; Glatzel, M A; Aguzzi, A (2005). Comment on "Failure to detect prion protein (PrPres) by immunohistochemistry in striated muscle tissues of animals experimentally inoculated with agents of transmissible spongiform encephalopathy". Veterinary Pathology, 42(1):107.

Ligios, C B; Sigurdson, C W; Santucciu, C; Carcassola, G; Manco, G; Basagni, M; Maestrale, C; Cancedda, M G; Madau, L; Aguzzi, A (2005). PrPSc in mammary glands of sheep affected by scrapie and mastitis. Nature Medicine, 11(11):1137-1138.

Aguzzi, A; Heikenwalder, M (2005). Prions, cytokines, and chemokines: a meeting in lymphoid organs. Immunity, 22(2):145-154.

Sigurdson, C B; Polymenidou, M; Aguzzi, A (2005). Reconstructing prions: fibril assembly from simple yeast to complex mammals. Neurodegenerative Diseases, 2(1):1-5.

Hugel, B; Martínez, M C; Kunzelmann, C; Blättler, T; Aguzzi, A; Freyssinet, J M (2004). Modulation of signal transduction through the cellular prion protein is linked to its incorporation in lipid rafts. Cellular and Molecular Life Sciences, 61(23):2998-3007.

Spaeth, N; Wyss, M T; Weber, B; Scheidegger, S; Lutz, A; Verwey, J; Radovanovic, I; Pahnke, J; Wild, D; Westera, G; Weishaupt, D; Hermann, D M; Kaser-Hotz, B; Aguzzi, A; Buck, A (2004). Uptake of 18F-fluorocholine, 18F-fluoroethyl-L-tyrosine, and 18F-FDG in acute cerebral radiation injury in the rat: implications for separation of radiation necrosis from tumor recurrence. Journal of Nuclear Medicine, 45(11):1931-1938.

Polymenidou, M; Heppner, F L; Pellicioli, E C; Urich, E; Miele, G; Braun, N; Wopfner, F; Schätzl, H M; Becher, B; Aguzzi, A (2004). Humoral immune response to native eukaryotic prion protein correlates with anti-prion protection. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 101(S2):14670-14676.

Pocchiari, M; Puopolo, M; Croes, E A; Budka, H; Gelpi, E; Collins, S; Lewis, V; Sutcliffe, T; Guilivi, A; Delasnerie-Laupretre, N; Brandel, J-P; Alperovitch, A; Zerr, I; Poser, S; Kretzschmar, H A; Ladogana, A; Rietvald, I; Mitrova, E; Martinez-Martin, P; de Pedro-Cuesta, J; Glatzel, M; Aguzzi, A; Cooper, S; Mackenzie, J; van Duijn, C M; Will, R G (2004). Predictors of survival in sporadic Creutzfeldt-Jakob disease and other human transmissible spongiform encephalopathies. Brain: A Journal of Neurology, 127(10):2348-2359.

Heppner, F L; Aguzzi, A (2004). Recent developments in prion immunotherapy. Current Opinion in Immunology, 16(5):594-598.

Aguzzi, A; Sigurdson, C J (2004). Antiprion immunotherapy: to suppress or to stimulate? Nature Reviews. Immunology, 4(9):725-736.

Raivich, G; Bohatschek, M; Da Costa, C; Iwata, O; Galiano, M; Hristova, M; Nateri, A S; Makwana, M; Riera-Sans, L; Wolfer, D P; Lipp, H P; Aguzzi, A; Wagner, E F; Behrens, A (2004). The AP-1 transcription factor c-Jun is required for efficient axonal regeneration. Neuron, 43(1):57-67.

Aguzzi, A; Heikenwalder, M; Miele, G (2004). Progress and problems in the biology, diagnostics, and therapeutics of prion diseases. Journal of Clinical Investigation, 114(2):153-160.

Prinz, M; Montrasio, F; Furukawa, H; van der Haar, M E; Schwarz, Petra; Rülicke, T; Giger, O T; Häusler, K G; Perez, D; Glatzel, M; Aguzzi, A (2004). Intrinsic resistance of oligodendrocytes to prion infection. Journal of Neuroscience, 24(26):5974-5981.

Glatzel, M; Giger, O; Braun, N; Aguzzi, A (2004). The peripheral nervous system and the pathogenesis of prion diseases. Current Molecular Medicine, 4(4):355-359.

Weissenberger, J; Loeffler, S; Kappeler, A; Kopf, M; Lukes, A; Afanasieva, T A; Aguzzi, A; Weis, J (2004). IL-6 is required for glioma development in a mouse model. Oncogene, 23(19):3308-3316.

Genoud, Nicolas; Behrens, A; Miele, G; Robay, D; Heppner, F L; Freigang, S; Aguzzi, A (2004). Disruption of Doppel prevents neurodegeneration in mice with extensive Prnp deletions. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 101(12):4198-4203.

Aguzzi, A; Glatzel, M (2004). vCJD tissue distribution and transmission by transfusion--a worst-case scenario coming true? Lancet, 363(9407):411-412.

Gandy, S; DeMattos, R B; Lemere, C A; Heppner, F L; Leverone, J; Aguzzi, A; Ershler, W B; Dai, J; Fraser, P; St George Hyslop, P; Holtzman, D M; Walker, L C; Keller, E T (2004). Alzheimer's Abeta vaccination of rhesus monkeys (Macaca mulatta). Mechanisms of Ageing and Development, 125(2):149-151.

Heikenwalder, M; Polymenidou, M; Junt, T; Sigurdson, C J; Wagner, H; Akira, S; Zinkernagel, R M; Aguzzi, A (2004). Lymphoid follicle destruction and immunosuppression after repeated CpG oligodeoxynucleotide administration. Nature Medicine, 10(2):187-192.

Glatzel, M; Giger, Olivier; Seeger, H; Aguzzi, A (2004). Variant Creutzfeldt-jakob disease: between lymphoid organs and brain. Trends in Microbiology, 12(2):51-53.

Aguzzi, A; Polymenidou, M (2004). Mammalian prion biology: one century of evolving concepts. Cell, 116(2):313-327.

Kovacs, G G; Lindeck-Pozza, E; Chimelli, L; Araújo, A Q C; Gabbai, A A; Ströbel, T; Glatzel, M; Aguzzi, A; Budka, H (2004). Creutzfeldt-Jakob disease and inclusion body myositis: abundant disease-associated prion protein in muscle. Annals of Neurology, 55(1):121-125.

Gandy, S; DeMattos, R B; Lemere, C A; Heppner, F L; Leverone, J; Aguzzi, A; Ershler, W B; Dai, J; Fraser, P; Hyslop, P S; Holtzman, D M; Walker, L C; Keller, E T (2004). Alzheimer A beta vaccination of rhesus monkeys (Macaca mulatta). Alzheimer Disease and Associated Disorders, 18(1):44-46.

Radovanovic, I; D'Angelo, M G; Aguzzi, A (2004). Angiogenesis in transgenic models of multistep angiogenesis. Journal of Neuro-Oncology, 50(1-2):89-98.

Heikenwalder, M; Prinz, M; Heppner, F L; Aguzzi, A (2004). Current concepts and controversies in prion immunopathology. Journal of Molecular Neuroscience, 23(1-2):3-12.

Aguzzi, A (2004). Host-microbe interactions: viruses a never-ending creativity contest. Current Opinion in Microbiology, 7(4):397-399.

Rossetti, A O; Bogousslavsky, J; Glatzel, M; Aguzzi, A (2004). Mimicry of variant Creutzfeldt-Jakob disease by sporadic Creutzfeldt-Jakob disease: importance of the pulvinar sign. Archives of Neurology, 61(3):445-446.

Aguzzi, A; Miele, G (2004). Recent advances in prion biology. Current Opinion in Neurology, 17(3):337-342.

Aguzzi, A (2004). Understanding the diversity of prions. Nature Cell Biology, 6(4):290-292.

Glatzel, M; Ott, P M; Linder, T; Gebbers, J O; Gmür, A; Wüst, W; Huber, G; Moch, H; Podvinec, M; Stamm, B; Aguzzi, A (2003). Human prion diseases: epidemiology and integrated risk assessment. Lancet Neurology, 2(12):757-763.

Glatzel, M; Abela, E; Maissen, M; Aguzzi, A (2003). Extraneural pathologic prion protein in sporadic Creutzfeldt-Jakob disease. New England Journal of Medicine, 349(19):1812-1820.

Aguzzi, A; Haass, C (2003). Games played by rogue proteins in prion disorders and Alzheimer's disease. Science, 302(5646):814-818.

Prinz, M; Heikenwalder, M; Junt, T; Schwarz, Petra; Glatzel, M; Heppner, F L; Fu, Y X; Lipp, M; Aguzzi, A (2003). Positioning of follicular dendritic cells within the spleen controls prion neuroinvasion. Nature, 425(6961):957-962.

Hutter, G; Heppner, F L; Aguzzi, A (2003). No superoxide dismutase activity of cellular prion protein in vivo. Biological Chemistry, 384(9):1279-1285.

Flechsig, E; Hegyi, I; Leimeroth, R; Zuniga, A; Rossi, D; Cozzio, A; Schwarz, Petra; Rülicke, T; Götz, J; Aguzzi, A; Weissmann, Charles (2003). Expression of truncated PrP targeted to Purkinje cells of PrP knockout mice causes Purkinje cell death and ataxia. The EMBO Journal, 22(12):3095-3101.

Lampe, J B; Schneider-Schaulies, S; Aguzzi, A (2003). Expression of the interferon-induced MxA protein in viral encephalitis. Neuropathology and Applied Neurobiology, 29(3):273-279.

Radovanovic, I; Casse, H; Aguzzi, A; Wang, Z Q; Zhang, C X (2003). Genetic ablation of the tumor suppressor menin causes lethality at mid-gestation with defects in multiple organs. Mechanisms of Development, 120(5):549-560.

Praus, M; Kettelgerdes, G; Baier, M; Holzhütter, H G; Jungblut, P R; Maissen, M; Epple, G; Schleuning, W D; Köttgen, E; Aguzzi, A; Gessner, R (2003). Stimulation of plasminogen activation by recombinant cellular prion protein is conserved in the NH2-terminal fragment PrP23-110. Thrombosis and Haemostasis, 89(5):812-819.

Meier, Philipp; Genoud, Nicolas; Prinz, M; Maissen, M; Rülicke, T; Zurbriggen, A; Raeber, A J; Aguzzi, A (2003). Soluble dimeric prion protein binds PrP(Sc) in vivo and antagonizes prion disease. Cell, 113(1):49-60.

Prinz, M; Huber, G; Macpherson, A J S; Heppner, F L; Glatzel, M; Eugster, H P; Wagner, N; Aguzzi, A (2003). Oral prion infection requires normal numbers of Peyer's patches but not of enteric lymphocytes. American Journal of Pathology, 162(4):1103-1111.

Prinz, M; Heikenwalder, M; Schwarz, Petra; Takeda, K; Akira, S; Aguzzi, A (2003). Prion pathogenesis in the absence of Toll-like receptor signalling. EMBO Reports, 4(2):195-199.

Rossetti, A O; Glatzel, M; Aguzzi, A; Janzer, R; Bogousslavsky, J (2003). Clinical and radiological mimicry of vCJD in a valine homozygous PrP(Sc) type 1 sCJD patient. Journal of Neurology, 250(4):491-493.

Aguzzi, A; Hardt, W-D (2003). Dangerous liaisons between a microbe and the prion protein. Journal of Experimental Medicine, 198(1):1-4.

Fischer, G; Ibrahim, S M; Brockmann, G A; Pahnke, J; Bartocci, E; Thiesen, H J; Serrano-Fernández, P; Möller, S (2003). Expressionview: visualization of quantitative trait loci and gene-expression data in Ensembl. Genome Biology, 4:R77.

Aguzzi, A; Heppner, F L; Heikenwalder, M; Prinz, M; Mertz, K; Seeger, H; Glatzel, M (2003). Immune system and peripheral nerves in propagation of prions to CNS. British Medical Bulletin, 66(1):141-159.

Aguzzi, A; Heikenwalder, M (2003). Prion diseases: Cannibals and garbage piles. Nature, 423(6936):127-129.

Genoud, N; Behrens, A; Arrighi, I; Aguzzi, A (2003). Prion proteins and infertility: insight from mouse models. Cytogenetic and Genome Research, 103(3-4):285-289.

Aguzzi, A (2003). Prions and the immune system: a journey through gut, spleen, and nerves. Advances in Immunology, 81:123-171.

Haegele, L; Ingold, B; Naumann, H; Tabatabai, G; Ledermann, B; Brandner, S (2003). Wnt signalling inhibits neural differentiation of embryonic stem cells by controlling bone morphogenetic protein expression. Molecular and Cellular Neuroscience, 24(3):696-708.

Thackray, A M; Klein, M A; Aguzzi, A; Bujdoso, R (2002). Chronic subclinical prion disease induced by low-dose inoculum. Journal of Virology, 76(5):2510-2517.

Prinz, M; Montrasio, F; Klein, M A; Schwarz, P; Priller, J P; Odermatt, B; Pfeffer, K; Aguzzi, A (2002). Lymph nodal prion replication and neuroinvasion in mice devoid of follicular dendritic cells. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 99(2):919-924.

Sisó, S; Puig, B; Varea, R; Vidal, E; Acín, C; Prinz, M; Montrasio, F; Badiola, J; Aguzzi, A; Pumarola, M; Ferrer, I (2002). Abnormal synaptic protein expression and cell death in murine scrapie. Acta Neuropathologica, 103(6):615-626.

Behrens, A; Genoud, N; Naumann, H; Rülicke, T J; Janett, F; Heppner, F L; Ledermann, B; Aguzzi, A (2002). Absence of the prion protein homologue Doppel causes male sterility. EMBO Journal, 21(14):3652-3658.

Glatzel, M; Pekarik, V; Lührs, T; Dittami, J; Aguzzi, A (2002). Analysis of the prion protein in primates reveals a new polymorphism in codon 226 (Y226F). Biological Chemistry, 383(6):1021-1025.

Wischhusen, J; Jung, G; Radovanovic, I; Beier, C; Steinbach, J P; Rimner, A; Huang, H; Schulz, J B; Ohgaki, H; Aguzzi, A; Rammensee, H G; Weller, M (2002). Identification of CD70-mediated apoptosis of immune effector cells as a novel immune escape pathway of human glioblastoma. Cancer Research, 62(9):2592-2599.

Heppner, F L; Aguzzi, A (2002). Immunität gegen Prionen? Deutsche Medizinische Wochenschrift, 127(7):328-330.

Glatzel, M; Rogivue, C; Ghani, A; Streffer, J R; Amsler, L; Aguzzi, A (2002). Incidence of Creutzfeldt-Jakob disease in Switzerland. Lancet, 360(9327):139-141.

Glatzel, M; Gottwein, J; Aguzzi, A (2002). Prionen als Motor der transmissiblen spongiformen Enzephalopathien. Schweizer Archiv für Tierheilkunde, 144(12):633-638.

Glatzel, M; Brandner, S; Klein, M A; Horstmann, S K; Aguzzi, A (2002). Prions--role of the peripheral nervous system. Virus Research, 82(1-2):53.

Behrens, A; Aguzzi, A (2002). Small is not beautiful: antagonizing functions for the prion protein PrP(C) and its homologue Dpl. Trends in Neurosciences, 25(3):150-154.

Rogivue, C; Gottwein, J; Aguzzi, A; Glatzel, M (2002). Transmissible spongiforme Enzephalopathien beim Menschen. Schweizer Archiv für Tierheilkunde, 144(12):685-690.

Aguzzi, A (2002). [The prion hypothesis and the human prion diseases.]. Berliner und Münchener Tierärztliche Wochenschrift, 115(3-4):91-98.

Zatloukal, K; Stumptner, C; Fuchsbichler, A; Heid, H; Schnoelzer, M; Kenner, L; Kleinert, R; Prinz, M G; Aguzzi, A; Denk, H (2002). p62 Is a common component of cytoplasmic inclusions in protein aggregation diseases. American Journal of Pathology, 160(1):255-263.

Parizek, P; Roeckl, C; Weber, J; Flechsig, E; Aguzzi, A; Raeber, A J (2001). Similar turnover and shedding of the cellular prion protein in primary lymphoid and neuronal cells. Journal of Biological Chemistry, 276(48):44627-44632.

Birchler, T; Seibl, R; Büchner, K; Loeliger, S; Seger, R; Hossle, J P; Aguzzi, A; Lauener, R P (2001). Human Toll-like receptor 2 mediates induction of the antimicrobial peptide human beta-defensin 2 in response to bacterial lipoprotein. European Journal of Immunology, 31(11):3131-3137.

Montesinos-Rongen, M; Hans, V H; Eis-Hübinger, A M; Prinz, M; Schaller, C; Van Roost, D; Aguzzi, A; Wiestler, O D; Deckert, M (2001). Human herpes virus-8 is not associated with primary central nervous system lymphoma in HIV-negative patients. Acta Neuropathologica, 102(5):489-495.

Glatzel, M; Aguzzi, A (2001). Sympathetic prions. The Scientific World Journal, 1:555-556.

Heppner, F L; Musahl, C; Arrighi, I; Klein, M A; Rülicke, T; Oesch, B; Zinkernagel, R M; Kalinke, U; Aguzzi, A (2001). Prevention of scrapie pathogenesis by transgenic expression of anti-prion protein antibodies. Science, 294(5540):178-182.

Aguzzi, A; Glatzel, M; Montrasio, F; Prinz, M; Heppner, F L (2001). Interventional strategies against prion diseases. Nature Reviews. Neuroscience, 2(10):745-749.

Glatzel, M; Aguzzi, A (2001). The shifting biology of prions. Brain Research Reviews, 36(2-3):241-248.

Steinbach, J P; Kozmik, Z; Pfeffer, P; Aguzzi, A (2001). Overexpression of Pax5 is not sufficient for neoplastic transformation of mouse neuroectoderm. International Journal of Cancer, 93(4):459-467.

Kaeser, P S; Klein, M A; Schwarz, P; Aguzzi, A (2001). Efficient lymphoreticular prion propagation requires PrP(c) in stromal and hematopoietic cells. Journal of Virology, 75(15):7097-7106.

Glatzel, M; Heppner, F L; Albers, K M; Aguzzi, A (2001). Sympathetic innervation of lymphoreticular organs is rate limiting for prion neuroinvasion. Neuron, 31(1):25-34.

Klein, M A; Kaeser, P S; Schwarz, P; Weyd, H; Xenarios, I; Zinkernagel, R M; Carroll, M C; Verbeek, J S; Botto, M; Walport, M J; Molina, H; Kalinke, U; Acha-Orbea, H; Aguzzi, A (2001). Complement facilitates early prion pathogenesis. Nature Medicine, 7(4):488-492.

Afanasieva, T A; Pekarik, V; Grazia D'Angelo, M; Klein, M A; Voigtländer, T; Stocking, C; Aguzzi, A (2001). Insertional mutagenesis of preneoplastic astrocytes by Moloney murine leukemia virus. Journal of NeuroVirology, 7(2):169-181.

Behrens, A; Brandner, S; Genoud, N; Aguzzi, A (2001). Normal neurogenesis and scrapie pathogenesis in neural grafts lacking the prion protein homologue Doppel. EMBO Reports, 2(4):347-352.

Montrasio, F; Cozzio, A; Flechsig, E; Rossi, D; Klein, M A; Rülicke, T; Raeber, A J; Vosshenrich, C A; Proft, J; Aguzzi, A; Weissmann, C (2001). B lymphocyte-restricted expression of prion protein does not enable prion replication in prion protein knockout mice. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 98(7):4034-4037.

Weissmann, C; Raeber, A J; Montrasio, F; Hegyi, I; Frigg, R; Klein, M A; Aguzzi, A (2001). Prions and the lymphoreticular system. Philosophical Transactions of the Royal Society B: Biological Sciences, 356(1406):177-184.

Rossi, D; Cozzio, A; Flechsig, E; Klein, M A; Rülicke, T; Aguzzi, A; Weissmann, C (2001). Onset of ataxia and Purkinje cell loss in PrP null mice inversely correlated with Dpl level in brain. The EMBO Journal, 20(4):694-702.

Aguzzi, A; Montrasio, F; Kaeser, P S (2001). Prions: health scare and biological challenge. Nature Reviews. Molecular Cell Biology, 2(2):118-126.

Aguzzi, A (2001). Blood simple prion diagnostics. Nature Medicine, 7(3):289-290.

Hainfellner, J A; Voigtländer, T; Ströbel, T; Mazal, P R; Maddalena, A S; Aguzzi, A; Budka, H (2001). Fibroblasts can express glial fibrillary acidic protein (GFAP) in vivo. Journal of Neuropathology and Experimental Neurology, 60(5):449-461.

Heppner, F L; Arrighi, I; Kalinke, U; Aguzzi, A (2001). Immunity against prions? Trends in Molecular Medicine, 7(11):477-479.

Heppner, F L; Prinz, M; Aguzzi, A (2001). Pathogenesis of prion diseases: possible implications of microglial cells. Progress in Brain Research, 132:737-750.

Aguzzi, A (2001). Peripheral prion pursuit. Journal of Clinical Investigation, 108(5):661-662.

Maissen, M; Roeckl, C; Glatzel, M; Goldmann, W; Aguzzi, A (2001). Plasminogen binds to disease-associated prion protein of multiple species. Lancet, 357(9273):2026-2028.

Blattler, T; Siegel, A M; Jochum, W; Aguzzi, A; Hess, K (2001). Primary cerebral amyloidoma. Neurology, 56(6):777.

Aguzzi, A; Brandner, S; Fischer, M B; Furukawa, H; Glatzel, M; Hawkins, C; Heppner, F L; Montrasio, F; Navarro, B; Parizek, P; Pekarik, V; Prinz, M; Raeber, A J; Röckl, C; Klein, M A (2001). Spongiform encephalopathies: insights from transgenic models. Advances in Virus Research, 56:313-352.

Raeber, A J; Montrasio, F; Hegyi, I; Frigg, R; Klein, M A; Aguzzi, A; Weissmann, C (2001). Studies on prion replication in spleen. Developmental Immunology, 8(3-4):291-304.

Heppner, F L; Christ, A D; Klein, M A; Prinz, M; Fried, M; Kraehenbuhl, J P; Aguzzi, A (2001). Transepithelial prion transport by M cells. Nature Medicine, 7(9):976-977.

Fischer, M B; Roeckl, C; Parizek, P; Schwarz, H P; Aguzzi, A (2000). Binding of disease-associated prion protein to plasminogen. Nature, 408(6811):479-483.

Klein, M A; Rüedi, D; Nozaki, M; Dell, E W; Diserens, A C; Seelentag, W; Janzer, R C; Aguzzi, A; Hegi, M E (2000). Reduced latency but no increased brain tumor penetrance in mice with astrocyte specific expression of a human p53 mutant. Oncogene, 19(47):5329-5337.

Heber, S; Herms, J; Gajic, V; Hainfellner, J A; Aguzzi, A; Rülicke, T; von Kretzschmar, H; von Koch, C; Sisodia, S; Tremml, P; Lipp, H P; Wolfer, D P; Müller, U (2000). Mice with combined gene knock-outs reveal essential and partially redundant functions of amyloid precursor protein family members. Journal of Neuroscience, 20(21):7951-7963.

Brandner, S; Klein, M A; Frigg, R; Pekarik, V; Parizek, P; Raeber, A; Glatzel, M; Schwarz, P; Rülicke, T; Weissmann, C; Aguzzi, A (2000). Neuroinvasion of prions: insights from mouse models. Experimental Physiology, 85(6):705-712.

Glatzel, M; Aguzzi, A (2000). PrP(C) expression in the peripheral nervous system is a determinant of prion neuroinvasion. Journal of General Virology, 81(11):2813-2821.

Aguzzi, A; Heppner, F L (2000). Pathogenesis of prion diseases: a progress report. Cell Death and Differentiation, 7(10):889-902.

Biffiger, K; Bartsch, S; Montag, D; Aguzzi, A; Schachner, M; Bartsch, U (2000). Severe hypomyelination of the murine CNS in the absence of myelin-associated glycoprotein and fyn tyrosine kinase. Journal of Neuroscience, 20(19):7430-7437.

Klein, M A; Aguzzi, A (2000). The neuroimmune interface in prion diseases. News in Physiological Sciences, 15(5):250-255.

Flechsig, E; Shmerling, D; Hegyi, I; Raeber, A J; Fischer, M B; Cozzio, A; von Mering, C; Aguzzi, A; Weissmann, C (2000). Prion protein devoid of the octapeptide repeat region restores susceptibility to scrapie in PrP knockout mice. Neuron, 27(2):399-408.

Chrast, R; Scott, H S; Madani, R; Huber, L; Wolfer, D P; Prinz, M; Aguzzi, A; Lipp, H P; Antonarakis, S E (2000). Mice trisomic for a bacterial artificial chromosome with the single-minded 2 gene (Sim2) show phenotypes similar to some of those present in the partial trisomy 16 mouse models of Down syndrome. Human Molecular Genetics, 9(12):1853-1864.

Loup, F; Wieser, H G; Yonekawa, Y; Aguzzi, A; Fritschy, J M (2000). Selective alterations in GABAA receptor subtypes in human temporal lobe epilepsy. Journal of Neuroscience, 20(14):5401-5419.

Benninger, Y; Marino, S; Hardegger, R; Weissmann, C; Aguzzi, A; Brandner, S (2000). Differentiation and histological analysis of embryonic stem cell-derived neural transplants in mice. Brain Pathology, 10(3):330-341.

Gao, B; Hagenbuch, B; Kullak-Ublick, G A; Benke, D; Aguzzi, A; Meier, P J (2000). Organic anion-transporting polypeptides mediate transport of opioid peptides across blood-brain barrier. Journal of Pharmacology and Experimental Therapeutics, 249(1):73-79.

Politopoulou, G; Seebach, J D; Schmugge, M; Schwarz, H P; Aguzzi, A (2000). Age-related expression of the cellular prion protein in human peripheral blood leukocytes. Haematologica / The Hematology Journal, 85(6):580-587.

Hegi, M E; Klein, M A; Rüedi, D; Chène, P; Hamou, M F; Aguzzi, A (2000). p53 transdominance but no gain of function in mouse brain tumor model. Cancer Research, 60(11):3019-3024.

Montrasio, F; Frigg, R; Glatzel, M; Klein, M A; Mackay, F; Aguzzi, A; Weissmann, C (2000). Impaired prion replication in spleens of mice lacking functional follicular dendritic cells. Science, 288(5469):1257-1259.

Glatzel, M; Aguzzi, A (2000). Peripheral pathogenesis of prion diseases. Microbes and Infection, 2(6):613-619.

Brandner, S; Klein, M A; Aguzzi, A (2000). Mechanisms of neuroinvasion by prions: molecular principles and present state of research. Swiss Medical Weekly, 130(12):435-442.

Glatzel, M; Flechsig, E; Navarro, B; Klein, M A; Paterna, J C; Büeler, H; Aguzzi, A (2000). Adenoviral and adeno-associated viral transfer of genes to the peripheral nervous system. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 97(1):442-447.

Nedelcu, J; Klein, M A; Aguzzi, A; Martin, E (2000). Resuscitative hypothermia protects the neonatal rat brain from hypoxic-ischemic injury. Brain Pathology, 10(1):61-71.

D'Angelo, M G; Afanasieva, T A; Aguzzi, A (2000). Angiogenesis in transgenic models of multistep carcinogenesis. Journal of Neuro-Oncology, 50(1-2):89-98.

Hergersberg, M; Glatzel, M; Capone, A; Achermann, S; Hagmann, A; Fischer, J; Ersch, J; Aguzzi, A; Boltshauser, E (2000). Deletions in the spinal muscular atrophy gene region in a newborn with neuropathy and extreme generalized muscular weakness. European Journal of Paediatric Neurology, 4(1):35-38.

Raeber, A J; Aguzzi, A (2000). Engulfment of prions in the germinal centre. Immunology Today, 21(2):66-67.

Aguzzi, A (2000). Prion diseases, blood and the immune system: concerns and reality. Haematologica / The Hematology Journal, 81(1):3-10.

Glatzel, M; Klein, M A; Brandner, S; Aguzzi, A (2000). Prions: from neurografts to neuroinvasion. Archives of virology. Supplementum, 16(3):3-12.

Aguzzi, A; Klein, M A; Montrasio, F; Pekarik, V; Brandner, S; Furukawa, H; Käser, P; Röckl, C; Glatzel, M (2000). Prions: pathogenesis and reverse genetics. Annals of the New York Academy of Sciences, 920:140-157.

Steinbach, J P; Weissenberger, J; Aguzzi, A (1999). Distinct phases of cryogenic tissue damage in the cerebral cortex of wild-type and c-fos deficient mice. Neuropathology and Applied Neurobiology, 25(6):468-480.

Frigg, R; Klein, M A; Hegyi, I; Zinkernagel, R M; Aguzzi, A (1999). Scrapie pathogenesis in subclinically infected B-cell-deficient mice. Journal of Virology, 73(11):9584-9588.

Maddalena, A S; Hainfellner, J A; Hegi, M E; Glatzel, M; Aguzzi, A (1999). No complementation between TP53 or RB-1 and v-src in astrocytomas of GFAP-v-src transgenic mice. Brain Pathology, 9(4):627-637.

Sancho, S; Magyar, J P; Aguzzi, A; Suter1, U (1999). Distal axonopathy in peripheral nerves of PMP22-mutant mice. Brain: A Journal of Neurology, 122(8):1563-1577.

Hefti, H P; Frese, M; Landis, H; Di Paolo, C; Aguzzi, A; Haller, O; Pavlovic, J (1999). Human MxA protein protects mice lacking a functional alpha/beta interferon system against La crosse virus and other lethal viral infections. Journal of Virology, 73(8):6984-6991.

Calogero, S; Grassi, F; Aguzzi, A; Voigtländer, T; Ferrier, P; Ferrari, S; Bianchi, M E (1999). The lack of chromosomal protein Hmg1 does not disrupt cell growth but causes lethal hypoglycaemia in newborn mice. Nature Genetics, 22(3):276-280.

Lichtlen, P; Georgiev, O; Schaffner, W; Aguzzi, A; Brandner, S (1999). The heavy metal-responsive transcription factor-1 (MTF-1) is not required for neural differentiation. Biological Chemistry, 380(6):711-715.

Raeber, A J; Klein, M A; Frigg, R; Flechsig, E; Aguzzi, A; Weissmann, C (1999). PrP-dependent association of prions with splenic but not circulating lymphocytes of scrapie-infected mice. The EMBO Journal, 18(10):2702-2706.

Raeber, A J; Sailer, A; Hegyi, I; Klein, M A; Rülicke, T; Fischer, M B; Brandner, S; Aguzzi, A; Weissmann, C (1999). Ectopic expression of prion protein (PrP) in T lymphocytes or hepatocytes of PrP knockout mice is insufficient to sustain prion replication. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 96(7):3987-3992.

Brandner, S; Klein, M A; Aguzzi, A (1999). A crucial role for B cells in neuroinvasive scrapie. Transfusion Clinique et Biologique, 6(1):17-23.

Theurillat, J P; Hainfellner, J A; Maddalena, A; Weissenberger, J; Aguzzi, A (1999). Early induction of angiogenetic signals in gliomas of GFAP-v-src transgenic mice. American Journal of Pathology, 154(2):581-590.

Nedelcu, J; Klein, M A; Aguzzi, A; Boesiger, P; Martin, E (1999). Biphasic edema after hypoxic-ischemic brain injury in neonatal rats reflects early neuronal and late glial damage. Pediatric Research, 46(3):297-304.

Pohl, U; Wick, W; Weissenberger, J; Steinbach, J P; Dichgans, J; Aguzzi, A; Weller, M (1999). Characterization of Tu-2449, a glioma cell line derived from a spontaneous tumor in GFAP-v-src-transgenic mice: comparison with established murine glioma cell lines. International Journal of Oncology, 15(4):829-834.

Weissmann, C; Aguzzi, A (1999). Perspectives: neurobiology. PrP's double causes trouble. Science, 286(5441):914-915.

Aguzzi, A; Brandner, S (1999). Shrinking prions: new folds to old questions. Nature Medicine, 5(5):486-487.

Shepherd, E J; Brettle, R P; Liberski, P P; Aguzzi, A; Ironside, J W; Simmonds, P; Bell, J E (1999). Spinal cord pathology and viral burden in homosexuals and drug users with AIDS. Neuropathology and Applied Neurobiology, 25(1):2-10.

Aguzzi, A; Brandner, S (1999). The genetics of prions--a contradiction in terms? Lancet, 354(S1):S122-S125.

Klein, M A; Frigg, R; Raeber, A J; Flechsig, E; Hegyi, I; Zinkernagel, R M; Weissmann, C; Aguzzi, A (1998). PrP expression in B lymphocytes is not required for prion neuroinvasion. Nature Medicine, 4(12):1429-1433.

Aguzzi, A (1998). Grafting mouse brains: from neurocarcinogenesis to neurodegeneration. EMBO Journal, 17(21):6107-6114.

Loup, F; Weinmann, O; Yonekawa, Y; Aguzzi, A; Wieser, H G; Fritschy, J M (1998). A highly sensitive immunofluorescence procedure for analyzing the subcellular distribution of GABA A receptor subunits in the human brain. Journal of Histochemistry and Cytochemistry, 46(10):1129-1139.

Raeber, A J; Brandner, S; Klein, M A; Benninger, Y; Musahl, C; Frigg, R; Roeckl, C; Fischer, M B; Weissmann, C; Aguzzi, A (1998). Transgenic and knockout mice in research on prion diseases. Brain Pathology, 8(4):715-733.

Mrkic, B; Pavlovic, J; Rülicke, T; Volpe, P; Buchholz, C J; Hourcade, D; Atkinson, J P; Aguzzi, A; Cattaneo, R (1998). Measles virus spread and pathogenesis in genetically modified mice. Journal of Virology, 72(9):7420-7427.

Zanusso, G; Liu, D; Ferrari, S; Hegyi, I; Yin, X; Aguzzi, A; Hornemann, S; Liemann, S; Glockshuber, R; Manson, J C; Brown, P; Petersen, R B; Gambetti, P; Sy, M S (1998). Prion protein expression in different species: analysis with a panel of new mAbs. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 95(15):8812-8816.

Cathomen, T; Mrkic, B; Spehner, D; Drillien, R; Naef, R; Pavlovic, J; Aguzzi, A; Billeter, M A; Cattaneo, R (1998). A matrix-less measles virus is infectious and elicits extensive cell fusion: consequences for propagation in the brain. The EMBO Journal, 17(14):3899-3908.

Aguzzi, A; Weissmann, C (1998). Prion diseases. Haemophilia, 4(4):619-627.

Günes, C; Heuchel, R; Georgiev, O; Müller, K H; Lichtlen, P; Blüthmann, H; Marino, S; Aguzzi, A; Schaffner, W (1998). Embryonic lethality and liver degeneration in mice lacking the metal-responsive transcriptional activator MTF-1. The EMBO Journal, 17(10):2846-2854.

Shmerling, D; Hegyi, I; Fischer, M B; Blättler, T; Brandner, S; Götz, J; Rülicke, T; Flechsig, E; Cozzio, A; von Mering, C; Hangartner, C; Aguzzi, A; Weissmann, C (1998). Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions. Cell, 93(2):203-214.

Lampe, J B; Marino, S; Rethwilm, A; Aguzzi, A (1998). Degeneration of the cerebellar granule cell layer in transgenic mice expressing genes of human foamy virus. Neuropathology and Applied Neurobiology, 24(1):36-43.

Brandner, S; Isenmann, S; Kühne, G; Aguzzi, A (1998). Identification of the end stage of scrapie using infected neural grafts. Brain Pathology, 8(1):19-27.

Sibilia, M; Steinbach, J P; Stingl, L; Aguzzi, A; Wagner, E F (1998). A strain-independent postnatal neurodegeneration in mice lacking the EGF receptor. EMBO Journal, 17(3):719-731.

Vingerhoets, F J; Hegyi, I; Aguzzi, A; Myers, P; Pizzolato, G; Landis, T (1998). An unusual case of Creutzfeldt-Jakob disease. Neurology, 51(2):617-619.

Kurz, D; Aguzzi, A; Scherer, T A (1998). Decompensated cor pulmonaleas the first manifestation of adult-onset myopathy. Respiration, 65(4):317-319.

Aguzzi, A; Huber, G F (1998). How to fight brain cell suicide, and feel good at it. Cell Death and Differentiation, 5(10):803-804.

Steinbach, J P; Müller, U; Leist, M; Li, Z W; Nicotera, P; Aguzzi, A (1998). Hypersensitivity to seizures in beta-amyloid precursor protein deficient mice. Cell Death and Differentiation, 5(10):858-866.

Aguzzi, A (1998). Protein conformation dictates prion strain. Nature Medicine, 4(10):1125-1126.

Aguzzi, A; Weissmann, C (1998). Spongiform encephalopathies. The prion's perplexing persistence. Nature, 392(6678):763-764.

Weissmann, C; Fischer, M; Raeber, A; Bueler, H; Sailer, A; Shmerling, D; Rülicke, T; Brandner, S; Aguzzi, A (1998). The use of transgenic mice in the investigation of transmissible spongiform encephalopathies. Revue scientifique et technique, 17(1):278-290.

Rovigatti, U; Afanasieva, T A; Brandner, S; Hainfellner, J A; Kiess, M; Maddalena, A; Malin, G; Rülicke, T; Steinbach, J; Weissenberger, J; Aguzzi, A (1998). Transgenic mice as research tools in neurocarcinogenesis. Journal of Neurovirology, 4(2):159-174.

Aguzzi, A; Raeber, A J (1998). Transgenic models of neurodegeneration. Neurodegeneration: of (transgenic) mice and men. Brain Pathology, 8(4):695-697.

Aguzzi, A; Klein, M A; Musahl, C; Raeber, A J; Blättler, T; Hegyi, I; Frigg, R; Brandner, S (1998). Use of brain grafts to study the pathogenesis of prion diseases. Essays in Biochemistry, 33:133-147.

Raeber, A J; Klein, M A; Frigg, R; Brandner, S; Blättler, T; Aguzzi, A (1998). [Significance of prion protein in transmission of prions and in pathogenesis of spongiform encephalopathies]. Wiener Medizinische Wochenschrift, 148(4):74-77.

Aguzzi, A; D'Angelo, M G; Klein, M A; Frigg, R; Fischer, M B; Raeber, A J; Röckl, C; Musahl, C; Hegyi, I; Brandner, S (1998). [The new research frontier on prion disease.]. Pathologica, 90(6):743-752.

Pruschy, M; Shi, Y Q; Crompton, N E; Steinbach, J P; Aguzzi, A; Glanzmann, C; Bodis, S (1997). The proto-oncogene c-fos mediates apoptosis in murine T-lymphocytes induced by ionizing radiation and dexamethasone. Biochemical and Biophysical Research Communications (BBRC), 241(2):519-524.

Weissmann, C; Aguzzi, A (1997). Bovine spongiform encephalopathy and early onset variant Creutzfeldt-Jakob disease. Current Opinion in Neurobiology, 7(5):695-700.

Blättler, T; Brandner, S; Raeber, A J; Klein, M A; Voigtländer, T; Weissmann, C; Aguzzi, A (1997). PrP-expressing tissue required for transfer of scrapie infectivity from spleen to brain. Nature, 389(6646):69-73.

Jochum, W; Weber, T; Frye, S; Hunsmann, G; Lüke, W; Aguzzi, A (1997). Detection of JC virus by anti-VP1 immunohistochemistry in brains with progressive multifocal leukoencephalopathy. Acta Neuropathologica, 94(3):226-231.

Bieniasz, P D; Erlwein, O; Aguzzi, A; Rethwilm, A; McClure, M O (1997). Gene transfer using replication-defective human foamy virus vectors. Virology, 235(1):65-72.

Schmidt, M; Niewiesk, S; Heeney, J; Aguzzi, A; Rethwilm, A (1997). Mouse model to study the replication of primate foamy viruses. Journal of General Virology, 78(8):1929-1933.

Aguzzi, A; Blättler, T; Klein, M A; Räber, A J; Hegyi, I; Frigg, R; Brandner, S; Weissmann, C (1997). Tracking prions: the neurografting approach. Cellular and Molecular Life Sciences, 53(6):485-495.

Weissenberger, J; Steinbach, J P; Malin, G; Spada, S; Rülicke, T; Aguzzi, A (1997). Development and malignant progression of astrocytomas in GFAP-v-src transgenic mice. Oncogene, 14(17):2005-2013.

Ozsahin, H; Arredondo-Vega, F X; Santisteban, I; Fuhrer, H; Tuchschmid, P; Jochum, W; Aguzzi, A; Lederman, H M; Fleischman, A; Winkelstein, J A; Seger, R A; Hershfield, M S (1997). Adenosine deaminase deficiency in adults. Blood, 89(8):2849-2855.

Hafezi, F; Steinbach, J P; Marti, A; Munz, K; Wang, Z Q; Wagner, E F; Aguzzi, A; Remé, C E (1997). The absence of c-fos prevents light-induced apoptotic cell death of photoreceptors in retinal degeneration in vivo. Nature Medicine, 3(3):346-349.

Sartoretti-Schefer, S; Wichmann, W; Aguzzi, A; Valavanis, A (1997). MR differentiation of adamantinous and squamous-papillary craniopharyngiomas. American Journal of Neuroradiology : AJNR, 18(1):77-87.

Klein, M A; Frigg, R; Flechsig, E; Raeber, A J; Kalinke, U; Bluethmann, H; Bootz, F; Suter, M; Zinkernagel, R M; Aguzzi, A (1997). A crucial role for B cells in neuroinvasive scrapie. Nature, 390(6661):687-690.

Raeber, A J; Race, R E; Brandner, S; Priola, S A; Sailer, A; Bessen, R A; Mucke, L; Manson, J C; Aguzzi, A; Oldstone, M B; Weissmann, C; Chesebro, B (1997). Astrocyte-specific expression of hamster prion protein (PrP) renders PrP knockout mice susceptible to hamster scrapie. EMBO Journal, 16(20):6057-6065.

Sherman, L; Jacoby, L B; Lampe, J; Pelton, P; Aguzzi, A; Herrlich, P; Ponta, H (1997). CD44 expression is aberrant in benign Schwann cell tumors possessing mutations in the neurofibromatosis type 2, but not type 1, gene. Cancer Research, 57(21):4889-4897.

Beutler, A S; Banck, M S; Aguzzi, A (1997). Curing rat glioblastoma: immunotherapy or graft rejection? Science, 276(5309):20-21.

Rumpel, H; Nedelcu, J; Aguzzi, A; Martin, E (1997). Late glial swelling after acute cerebral hypoxia-ischemia in the neonatal rat: a combined magnetic resonance and histochemical study. Pediatric Research, 42(1):54-59.

Aguzzi, A (1997). Neuro-immune connection in spread of prions in the body? Lancet, 349(9054):742-743.

Aguzzi, A; Raeber, A; Blättler, T; Flechsig, E; Klein, M; Weissmann, C; Brandner, S (1997). Neurotoxicity and neuroinvasiveness of prions. Journal of NeuroVirology, 3(S1):S23-S24.

Vajtai, I; Varga, Z; Aguzzi, A (1997). Pleomorphic xanthoastrocytoma with gangliogliomatous component. Pathology, Research and Practice, 193(9):617-621.

Aguzzi, A; Collinge, J (1997). Post-exposure prophylaxis after accidental prion inoculation. Lancet, 350(9090):1519-1520.

Aguzzi, A; Weissmann, C (1997). Prion research: the next frontiers. Nature, 389(6653):795-798.

Aguzzi, A (1997). Prions and antiprions. Biological Chemistry, 378(12):1393-1395.

Baerlocher, K E; Steinmann, B; Aguzzi, A; Krähenbühl, S; Roe, C R; Vianey-Saban, C (1997). Short-chain acyl-CoA dehydrogenase deficiency in a 16-year-old girl with severe muscle wasting and scoliosis. Journal of Inherited Metabolic Disease, 20(3):427-431.

Serio, G; Aguzzi, A (1997). Spindle and giant cell carcinoma of the colon. Histopathology, 30(4):383-385.

Weber, T; Aguzzi, A (1997). The spectrum of transmissible spongiform encephalopathies. Intervirology, 40(2-3):198-212.

Aguzzi, A; Maddalena, A; Brandner, S; Klein, M (1997). [Molecular pathogenesis of spongiform encephalopathy.]. Pathologica, 89(5):481-490.

Brandner, S; Raeber, A; Sailer, A; Blättler, T; Fischer, M B; Weissmann, C; Aguzzi, A (1996). Normal host prion protein (PrPC) is required for scrapie spread within the central nervous system. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 93(23):13148-13151.

Ogata, N; Jochum, W; Aguzzi, A; Fournier, J Y; Yonekawa, Y (1996). Total removal of a primary intracranial squamous cell carcinoma invading the brain stem. Surgical Neurology, 46(5):477-480.

Magyar, J P; Martini, R; Ruelicke, T; Aguzzi, A; Adlkofer, K; Dembic, Z; Zielasek, J; Toyka, K V; Suter, U (1996). Impaired differentiation of Schwann cells in transgenic mice with increased PMP22 gene dosage. Journal of Neuroscience, 16(17):5351-5360.

Fritschy, J M; Brandner, S; Aguzzi, A; Koedood, M; Luscher, B; Mitchell, P J (1996). Brain cell type specificity and gliosis-induced activation of the human cytomegalovirus immediate-early promoter in transgenic mice. Journal of Neuroscience, 16(7):2275-2282.

Isenmann, S; Brandner, S; Kühne, G; Boner, J; Aguzzi, A (1996). Comparative in vivo and pathological analysis of the blood-brain barrier in mouse telencephalic transplants. Neuropathology and Applied Neurobiology, 22(2):118-128.

Isenmann, S; Brandner, S; Sure, U; Aguzzi, A (1996). Telencephalic transplants in mice: characterization of growth and differentiation patterns. Neuropathology and Applied Neurobiology, 22(2):108-117.

Tief, K; Schmidt, A; Aguzzi, A; Beermann, F (1996). Tyrosinase is a new marker for cell populations in the mouse neural tube. Developmental Dynamics, 205(4):445-456.

Fischer, M B; Rülicke, T; Raeber, A; Sailer, A; Moser, M; Oesch, B; Brandner, S; Aguzzi, A; Weissmann, C (1996). Prion protein (PrP) with amino-proximal deletions restoring susceptibility of PrP knockout mice to scrapie. The EMBO Journal, 15(6):1255-1264.

Tschopp, R R; Brandner, S; Marino, S; Bothe, K; Horak, I; Rethwilm, A; Aguzzi, A (1996). Analysis of the determinants of neurotropism and neurotoxicity of HFV in transgenic mice. Virology, 216(2):338-346.

Brandner, S; Isenmann, S; Raeber, A; Fischer, M B; Sailer, A; Kobayashi, Y; Marino, S; Weissmann, C; Aguzzi, A (1996). Normal host prion protein necessary for scrapie-induced neurotoxicity. Nature, 379(6563):339-343.

Aguzzi, A (1996). Between cows and monkeys. Nature, 381(6585):734-735.

Pergami, P; Arbustini, E; Butti, G; Karau, J; Aguzzi, A; Poloni, T E; Montalbetti, L; Egitto, M G; Simonetti, F; Savoldi, F; Ceroni, M (1996). Disseminated encephalitis following streptococcal infection. Italian Journal of Neurological Sciences, 17(1):87-91.

Vajtai, I; Varga, Z; Aguzzi, A (1996). MIB-1 immunoreactivity reveals different labelling in low-grade and in malignant epithelial neoplasms of the choroid plexus. Histopathology, 29(2):147-151.

Müller, U; Cristina, N; Li, Z W; Wolfer, D P; Lipp, H P; Rülicke, T; Brandner, S; Aguzzi, A; Weissman, C (1996). Mice homozygous for a modified beta-amyloid precursor protein (beta APP) gene show impaired behavior and high incidence of agenesis of the corpus callosum. Annals of the New York Academy of Sciences, 777:65-73.

Isenmann, S; Brandner, S; Aguzzi, A (1996). Neuroectodermal grafting: a new tool for the study of neurodegenerative diseases. Histology and Histopathology, 11(4):1063-1073.

Chazot, G; Broussolle, E; Lapras, C l; Blättler, T; Aguzzi, A; Kopp, N (1996). New variant of Creutzfeldt-Jakob disease in a 26-year-old French man. Lancet, 347(9009):1181.

Aguzzi, A (1996). Pathogenesis of spongiform encephalopathies: an update. International Archives of Allergy and Immunology, 110(2):99-106.

Lindberg, R L; Porcher, C; Grandchamp, B; Ledermann, B; Bürki, K; Brandner, S; Aguzzi, A; Meyer, U A (1996). Porphobilinogen deaminase deficiency in mice causes a neuropathy resembling that of human hepatic porphyria. Nature Genetics, 12(2):195-199.

Aguzzi, A; Marino, S; Tschopp, R; Rethwilm, A (1996). Regulation of expression and pathogenic potential of human foamy virus in vitro and in transgenic mice. Current Topics in Microbiology and Immunology, 206:243-273.

Aguzzi, A; Weissmann, C (1996). Sleepless in Bologna: transmission of fatal familial insomnia. Trends in Microbiology, 4(4):129-132.

Aguzzi, A; Weissmann, C (1996). Spongiform encephalopathies: a suspicious signature. Nature, 383(6602):666-667.

Weissmann, C; Fischer, M; Raeber, A; Büeler, H; Sailer, A; Shmerling, D; Rülicke, T; Brandner, S; Aguzzi, A (1996). The role of PrP in pathogenesis of experimental scrapie. Cold Spring Harbor Symposia on Quantitative Biology, 61:511-522.

Varga, Z; Vajtai, I; Aguzzi, A (1996). The standard isoform of CD44 is preferentially expressed in atypical papillomas and carcinomas of the choroid plexus. Pathology, Research and Practice, 192(12):1225-1231.

Weissmann, C; Fischer, M; Raeber, A; Büeler, H; Sailer, A; Shmerling, D; Rülicke, T; Brandner, S; Aguzzi, A (1996). The use of transgenic mice in the investigation of transmissible spongiform encephalopathies. International Journal of Experimental Pathology, 77(6):283-293.

Aguzzi, A; Brandner, S; Marino, S; Steinbach, J P (1996). Transgenic and knockout mice in the study of neurodegenerative diseases. Journal of Molecular Medicine, 74(3):111-126.

Varga, Z; Vajtai, I; Marino, S; Schäuble, B; Yonekawa, Y; Aguzzi, A (1996). Tubular adenoma of the choroid plexus: evidence for glandular differentiation of the neuroepithelium. Pathology, Research and Practice, 192(8):840-844.

Steinbach, J P; Aguzzi, A (1996). XVI Winter meeting of the Swiss Society of Neuropathology, St Moritz, 20-23 March 1996. Neuropathology and Applied Neurobiology, 22(3):261-263.

Budka, H; Aguzzi, A; Brown, P; Brucher, J M; Bugiani, O; Collinge, J; Diringer, H; Gullotta, F; Haltia, M; Hauw, J J; Ironside, J W; Kretzschmar, H A; Lantos, P L; Masullo, C; Pocchiari, M; Schlote, W; Tateishi, J; Will, R G (1996). [Consensus report: tissue handling in suspected Creutzfeldt-Jakob disease and other spongiform encephalopathies (prion diseases) in the human. European Union Biomed-1 Concerted Action]. Der Pathologe, 17(2):171-175.

Isenmann, S; Molthagen, M; Brandner, S; Bartsch, U; Kühne, G; Magyar, J P; Sure, U; Schachner, M; Aguzzi, A (1995). The AMOG/beta 2 subunit of Na,K-ATPase is not necessary for long-term survival of telencephalic grafts. Glia, 15(4):377-388.

Adlkofer, K; Martini, R; Aguzzi, A; Zielasek, J; Toyka, K V; Suter, U (1995). Hypermyelination and demyelinating peripheral neuropathy in Pmp22-deficient mice. Nature Genetics, 11(3):274-280.

Aguzzi, A; Brandner, S; Isenmann, S; Steinbach, J P; Sure, U (1995). Transgenic and gene disruption techniques in the study of neurocarcinogenesis. Glia, 15(3):348-364.

Bladt, F; Riethmacher, D; Isenmann, S; Aguzzi, A; Birchmeier, C (1995). Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb bud. Nature, 376(6543):768-771.

Marino, S; Kretschmer, C; Brandner, S; Cavard, C; Zider, A; Briand, P; Isenmann, S; Wagner, E F; Aguzzi, A (1995). Activation of HIV transcription by human foamy virus in transgenic mice. Laboratory Investigation, 73(1):103-110.

Kozmik, Z; Sure, U; Rüedi, D; Busslinger, M; Aguzzi, A (1995). Deregulated expression of PAX5 in medulloblastoma. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 92(12):5709-5713.

Weller, M; Malipiero, U; Aguzzi, A; Reed, J C; Fontana, A (1995). Protooncogene bcl-2 gene transfer abrogates Fas/APO-1 antibody-mediated apoptosis of human malignant glioma cells and confers resistance to chemotherapeutic drugs and therapeutic irradiation. Journal of Clinical Investigation, 95(6):2633-2643.

Rainov, N G; Lübbe, J; Renshaw, J; Pritchard-Jones, K; Lüthy, A R; Aguzzi, A (1995). Association of Wilms' tumor with primary brain tumor in siblings. Journal of Neuropathology and Experimental Neurology, 54(2):214-223.

Hergersberg, M; Matsuo, K; Gassmann, M; Schaffner, W; Lüscher, B; Rülicke, T; Aguzzi, A (1995). Tissue-specific expression of a FMR1/beta-galactosidase fusion gene in transgenic mice. Human Molecular Genetics, 4(3):359-366.

Stuart, E T; Kioussi, C; Aguzzi, A; Gruss, P (1995). PAX5 expression correlates with increasing malignancy in human astrocytomas. Clinical Cancer Research, 1(2):207-214.

Sure, U; Bertalanffy, H; Isenmann, S; Brandner, S; Berghorn, W J; Seeger, W; Aguzzi, A (1995). Secondary manifestation of medulloblastoma: metastases and local recurrences in 66 patients. Acta Neurochirurgica, 136(3-4):117-126.

Aguzzi, A; Theuring, F (1994). Improved in situ beta-galactosidase staining for histological analysis of transgenic mice. Histochemistry and Cell Biology, 102(6):477-481.

This list was generated on Fri Nov 17 22:03:41 2017 CET.