Publication: Effects of seeding adipose-derived stem cells on electrospun nanocomposite used as chest wall graft in a murine model
Effects of seeding adipose-derived stem cells on electrospun nanocomposite used as chest wall graft in a murine model
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Buschmann, J., Balli, E., Hess, S. C., Stark, W. J., Cinelli, P., Märsmann, S., Welti, M., Weder, W., & Jungraithmayr, W. (2017). Effects of seeding adipose-derived stem cells on electrospun nanocomposite used as chest wall graft in a murine model. Injury, 48(10), 2080–2088. https://doi.org/10.1016/j.injury.2017.08.004
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OBJECTIVES Malignant neoplasms infiltrating the chest wall often requires resection of the thoracic wall. To replace the defect, Gore-Tex(®) is usually employed as the gold standard material, however, Gore-Tex(®) is inert and not degradable. Novel materials are nowadays available which allow a full bio-integration due to their non-toxic degradability. Additionally, stem cell seeding has the capacity to reduce inflammatory response towards such grafts, thus integrating it better into the host organism.
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Buschmann, J., Balli, E., Hess, S. C., Stark, W. J., Cinelli, P., Märsmann, S., Welti, M., Weder, W., & Jungraithmayr, W. (2017). Effects of seeding adipose-derived stem cells on electrospun nanocomposite used as chest wall graft in a murine model. Injury, 48(10), 2080–2088. https://doi.org/10.1016/j.injury.2017.08.004