Publication: In vivo and in vitro propagation and transmission of Toggenburg orbivirus
In vivo and in vitro propagation and transmission of Toggenburg orbivirus
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Planzer, J., Kaufmann, C., Worwa, G., Gavier-Widén, D., Hofmann, M. A., Chaignat, V., & Thür, B. (2011). In vivo and in vitro propagation and transmission of Toggenburg orbivirus. Research in Veterinary Science, 91(3), e163–e168. https://doi.org/10.1016/j.rvsc.2011.03.007
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The Toggenburg orbivirus (TOV), a recently discovered virus related to bluetongue virus (BTV), has been identified in goats in Switzerland, Italy and Germany. Isolation of TOV in vitro has not yet been achieved and the transmission mechanisms are still unknown. In the experimental infection of pregnant goats described here, TOV could not be detected in secretion/excretion samples or fetal blood. Material from the goat experiment was used as inoculum for propagating the virus in vitro. To enhance the infectivity of TOV several modified
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Planzer, J., Kaufmann, C., Worwa, G., Gavier-Widén, D., Hofmann, M. A., Chaignat, V., & Thür, B. (2011). In vivo and in vitro propagation and transmission of Toggenburg orbivirus. Research in Veterinary Science, 91(3), e163–e168. https://doi.org/10.1016/j.rvsc.2011.03.007