Publication: Allogeneic hematopoietic stem-cell transplantation for leukocyte adhesion deficiency
Allogeneic hematopoietic stem-cell transplantation for leukocyte adhesion deficiency
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Qasim, W., Cavazzana-Calvo, M., Davies, E. G., Davis, J., Duval, M., Eames, G., Farinha, N., Filopovich, A., Fischer, A., Friedrich, W., Gennery, A., Heilmann, C., Landais, P., Horwitz, M., Porta, F., Sedlacek, P., Seger, R., Slatter, M., Slatten, M., … Veys, P. (2009). Allogeneic hematopoietic stem-cell transplantation for leukocyte adhesion deficiency. Pediatrics, 123(3), 836–840. https://doi.org/10.1542/peds.2008-1191
Abstract
Abstract
Abstract
OBJECTIVES: Leukocyte adhesion deficiency is a rare primary immune disorder caused by defects of the CD18 beta-integrin molecule on immune cells. The condition usually presents in early infancy and is characterized by deep tissue infections, leukocytosis with impaired formation of pus, and delayed wound healing. Allogeneic hematopoietic stem-cell transplantation offers the possibility of curative therapy, and with patient numbers at any individual center being limited, we surveyed the transplant experience at 14 centers worldwide. MET
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Creators (Authors)
- Qasim, W
- Cavazzana-Calvo, M
- Davies, E G
- Davis, J
- Duval, M
- Eames, G
- Farinha, N
- Filopovich, A
- Fischer, A
- Friedrich, W
- Gennery, A
- Heilmann, C
- Landais, P
- Horwitz, M
- Porta, F
- Sedlacek, P
- Seger, R
- Slatten, M
- Teague, L
- Eapen, M
- Veys, P
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Citations
Qasim, W., Cavazzana-Calvo, M., Davies, E. G., Davis, J., Duval, M., Eames, G., Farinha, N., Filopovich, A., Fischer, A., Friedrich, W., Gennery, A., Heilmann, C., Landais, P., Horwitz, M., Porta, F., Sedlacek, P., Seger, R., Slatter, M., Slatten, M., … Veys, P. (2009). Allogeneic hematopoietic stem-cell transplantation for leukocyte adhesion deficiency. Pediatrics, 123(3), 836–840. https://doi.org/10.1542/peds.2008-1191
