Publication: Navigating Hemolysis, Hemoglobin Toxicity, and Its Renal Implications in Cardiac Surgery
Navigating Hemolysis, Hemoglobin Toxicity, and Its Renal Implications in Cardiac Surgery
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Schaer, D. J., Schaer, C. A., Humar, R., Vallelian, F., Henderson, R., Tanaka, K. A., Levy, J. H., & Buehler, P. W. (2024). Navigating Hemolysis, Hemoglobin Toxicity, and Its Renal Implications in Cardiac Surgery. Anesthesiology, 141(6), 1162–1174. https://doi.org/10.1097/aln.0000000000005109
Abstract
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Abstract
Cardiopulmonary bypass–induced hemolysis is linked to acute kidney injury in cardiac surgery. Emerging therapies targeting cell-free hemoglobin (CFHb), like haptoglobin, nitric oxide (NO), and antioxidants, show promise in reducing kidney injury, highlighting the need for further research.
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- Schaer, Dominik J
- Schaer, Christian A
- Humar, Rok
- Vallelian, Florence
- Henderson, Reney
- Tanaka, Kenichi A
- Levy, Jerrold H
- Buehler, Paul W
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Citations
Schaer, D. J., Schaer, C. A., Humar, R., Vallelian, F., Henderson, R., Tanaka, K. A., Levy, J. H., & Buehler, P. W. (2024). Navigating Hemolysis, Hemoglobin Toxicity, and Its Renal Implications in Cardiac Surgery. Anesthesiology, 141(6), 1162–1174. https://doi.org/10.1097/aln.0000000000005109
