Publication: Hair-cortisol and hair-BDNF as biomarkers of tinnitus loudness and distress in chronic tinnitus
Hair-cortisol and hair-BDNF as biomarkers of tinnitus loudness and distress in chronic tinnitus
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Basso, L., Boecking, B., Neff, P., Brueggemann, P., Peters, E. M. J., & Mazurek, B. (2022). Hair-cortisol and hair-BDNF as biomarkers of tinnitus loudness and distress in chronic tinnitus. Scientific Reports, 12, 1934. https://doi.org/10.1038/s41598-022-04811-0
Abstract
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Abstract
The role of stress and its neuroendocrine mediators in tinnitus is unclear. In this study, we measure cortisol as an indicator of hypothalamus-pituitary-adrenal (HPA) axis alterations and brain-derived neurotrophic factor (BDNF) as a marker of adaptive neuroplasticity in hair of chronic tinnitus patients to investigate relationships with tinnitus-related and psychological factors. Cross-sectional data from chronic tinnitus inpatients were analyzed. Data collection included hair sampling, pure tone audiometry, tinnitus pitch and loudne
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- Basso, Laura
- Boecking, Benjamin
- Neff, Patrick
- Brueggemann, Petra
- Peters, Eva M J
- Mazurek, Birgit
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Basso, L., Boecking, B., Neff, P., Brueggemann, P., Peters, E. M. J., & Mazurek, B. (2022). Hair-cortisol and hair-BDNF as biomarkers of tinnitus loudness and distress in chronic tinnitus. Scientific Reports, 12, 1934. https://doi.org/10.1038/s41598-022-04811-0
