Publication: The thalamus and its subnuclei: a gateway to obsessive-compulsive disorder
The thalamus and its subnuclei: a gateway to obsessive-compulsive disorder
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Weeland, C. J., Kasprzak, S., de Joode, N. T., et al, Brem, S., & Walitza, S. (2021). The thalamus and its subnuclei: a gateway to obsessive-compulsive disorder (No. 21262530; MedRxiv). https://doi.org/10.1101/2021.09.06.21262530
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Objective Higher thalamic volume has been found in children with obsessive-compulsive disorder (OCD) and children with clinical-level symptoms within the general population. Particular thalamic subregions may drive these differences. The ENIGMA-OCD working group conducted mega- and meta-analyses to study thalamic subregional volume in OCD across the lifespan.
Method Structural T1-weighted brain magnetic resonance imaging (MRI) scans from 2,649 OCD patients and 2,774 healthy controls across 29 sites (50 datasets) were processed using
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Weeland, C. J., Kasprzak, S., de Joode, N. T., et al, Brem, S., & Walitza, S. (2021). The thalamus and its subnuclei: a gateway to obsessive-compulsive disorder (No. 21262530; MedRxiv). https://doi.org/10.1101/2021.09.06.21262530
