Publication: Reduced Firing of Nucleus Accumbens Parvalbumin Interneurons Impairs Risk Avoidance in DISC1 Transgenic Mice
Date
Date
Date
2021
Journal Article
Published version
Abstract
Abstract
Abstract
A strong animal survival instinct is to approach objects and situations that are of benefit and to avoid risk. In humans, a large proportion of mental disorders are accompanied by impairments in risk avoidance. One of the most important genes involved in mental disorders is disrupted-in-schizophrenia-1 (DISC1), and animal models in which this gene has some level of dysfunction show emotion-related impairments. However, it is not known whether DISC1 mouse models have an impairment in avoiding potential risks. In the present study, we u
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2 since deposited on 2022-03-28
Acq. date: 2025-11-12
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1 since deposited on 2022-03-28
Acq. date: 2025-11-12
Additional indexing
Creators (Authors)
- Zhou, Xinyi
- Wu, Bifeng
- Liu, Wenhao
- Xiao, Qian
- He, Wei
- Zhou, Ying
- Wei, Pengfei
- Zhang, Xu
- Liu, Yue
- Wang, Jie
- He, Jufang
- Zhang, Zhigang
- Li, Weidong
- Wang, Liping
- Tu, Jie
Volume
Volume
Volume
37
Number
Number
Number
9
Page range/Item number
Page range/Item number
Page range/Item number
1325
Page end
Page end
Page end
1338
Item Type
Item Type
Item Type
Journal Article
In collections
Keywords
General Medicine, Physiology, General Neuroscience
Language
Language
Language
English
Publication date
Publication date
Publication date
2021-09-01
Date available
Date available
Date available
2022-03-28
ISSN or e-ISSN
ISSN or e-ISSN
ISSN or e-ISSN
1995-8218
OA Status
OA Status
OA Status
Hybrid
Free Access at
Free Access at
Free Access at
DOI
Publisher DOI
Metrics
Downloads
2 since deposited on 2022-03-28
Acq. date: 2025-11-12
Views
1 since deposited on 2022-03-28
Acq. date: 2025-11-12
Hybrid Open Access
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