Publication: Podoplanin-positive cells are a hallmark of encapsulating peritoneal sclerosis
Podoplanin-positive cells are a hallmark of encapsulating peritoneal sclerosis
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Braun, N., Alscher, D. M., Fritz, P., Edenhofer, I., Kimmel, M., Gaspert, A., Reimold, F., Bode-Lesniewska, B., Ziegler, U., Biegger, D., Wüthrich, R. P., & Segerer, S. (2011). Podoplanin-positive cells are a hallmark of encapsulating peritoneal sclerosis. Nephrology, Dialysis, Transplantation, 26(3), 1033–1041. https://doi.org/10.1093/ndt/gfq488
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BACKGROUND: Encapsulating peritoneal sclerosis (EPS) and simple peritoneal sclerosis are important complications of long-term peritoneal dialysis (PD). Podoplanin is expressed by mesothelial cells and lymphatic vessels, which are involved in inflammatory reactions in the peritoneal cavity. METHODS: We studied 69 peritoneal biopsies from patients on PD (n = 16), patients with EPS (n = 18) and control biopsies taken at the time of hernia repair (n = 15) or appendectomy (n = 20). Immunohistochemistry was performed to localize podoplanin.
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Braun, N., Alscher, D. M., Fritz, P., Edenhofer, I., Kimmel, M., Gaspert, A., Reimold, F., Bode-Lesniewska, B., Ziegler, U., Biegger, D., Wüthrich, R. P., & Segerer, S. (2011). Podoplanin-positive cells are a hallmark of encapsulating peritoneal sclerosis. Nephrology, Dialysis, Transplantation, 26(3), 1033–1041. https://doi.org/10.1093/ndt/gfq488