Publication: Rapid cellular perception of gravitational forces in human jurkat T cells and transduction into gene expression regulation
Rapid cellular perception of gravitational forces in human jurkat T cells and transduction into gene expression regulation
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Thiel, C. S., Christoffel, S., Tauber, S., Vahlensieck, C., de Zélicourt, D., Layer, L. E., Lauber, B., Polzer, J., & Ullrich, O. (2020). Rapid cellular perception of gravitational forces in human jurkat T cells and transduction into gene expression regulation. International Journal of Molecular Sciences, 21(2), 514. https://doi.org/10.3390/ijms21020514
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Cellular processes are influenced in many ways by changes in gravitational force. In previous studies, we were able to demonstrate, in various cellular systems and research platforms that reactions and adaptation processes occur very rapidly after the onset of altered gravity. In this study we systematically compared differentially expressed gene transcript clusters (TCs) in human Jurkat T cells in microgravity provided by a suborbital ballistic rocket with vector-averaged gravity (vag) provided by a 2D clinostat. Additionally, we inc
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Thiel, C. S., Christoffel, S., Tauber, S., Vahlensieck, C., de Zélicourt, D., Layer, L. E., Lauber, B., Polzer, J., & Ullrich, O. (2020). Rapid cellular perception of gravitational forces in human jurkat T cells and transduction into gene expression regulation. International Journal of Molecular Sciences, 21(2), 514. https://doi.org/10.3390/ijms21020514