Publication: Long non-coding RNAs H19 and NKILA are associated with the risk of death and lacunar stroke in the elderly population
Long non-coding RNAs H19 and NKILA are associated with the risk of death and lacunar stroke in the elderly population
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Lapikova-Bryhinska, T., Ministrini, S., Puspitasari, Y. M., Kraler, S., Mohamed, S. A., Costantino, S., Paneni, F., Khetsuriani, M., Bengs, S., Liberale, L., Montecucco, F., Krampla, W., Riederer, P., Hinterberger, M., Fischer, P., Lüscher, T. F., Grünblatt, E., Akhmedov, A., & Camici, G. G. (2024). Long non-coding RNAs H19 and NKILA are associated with the risk of death and lacunar stroke in the elderly population. European Journal of Internal Medicine, 123, 94–101. https://doi.org/10.1016/j.ejim.2023.11.013
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Introduction: Differential expression of long non-coding RNAs (lncRNAs) is a hallmark of cardiovascular aging, cerebrovascular diseases, and neurodegenerative disorders. This research article investigates the association between a panel of lncRNAs and the risk of death and ischemic stroke in a cohort of non-institutionalized elderly subjects.
Method: A total of 361 healthy individuals aged 75 years old, prospectively recruited in the Vienna Transdanube Aging (VITA) cohort, were included. Expression of lncRNAs at baseline was assessed
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Lapikova-Bryhinska, T., Ministrini, S., Puspitasari, Y. M., Kraler, S., Mohamed, S. A., Costantino, S., Paneni, F., Khetsuriani, M., Bengs, S., Liberale, L., Montecucco, F., Krampla, W., Riederer, P., Hinterberger, M., Fischer, P., Lüscher, T. F., Grünblatt, E., Akhmedov, A., & Camici, G. G. (2024). Long non-coding RNAs H19 and NKILA are associated with the risk of death and lacunar stroke in the elderly population. European Journal of Internal Medicine, 123, 94–101. https://doi.org/10.1016/j.ejim.2023.11.013