Publication: Pathway analysis in attention deficit hyperactivity disorder: An ensemble approach
Pathway analysis in attention deficit hyperactivity disorder: An ensemble approach
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Mooney, M. A., McWeeney, S. K., Faraone, S. V., Hinney, A., Hebebrand, J., Nigg, J. T., & Wilmot, B. (2016). Pathway analysis in attention deficit hyperactivity disorder: An ensemble approach. American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 171(6), 815–826. https://doi.org/10.1002/ajmg.b.32446
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Despite a wealth of evidence for the role of genetics in attention deficit hyperactivity disorder (ADHD), specific and definitive genetic mechanisms have not been identified. Pathway analyses, a subset of gene-set analyses, extend the knowledge gained from genome-wide association studies (GWAS) by providing functional context for genetic associations. However, there are numerous methods for association testing of gene sets and no real consensus regarding the best approach. The present study applied six pathway analysis methods to iden
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- Mooney, Michael A
- McWeeney, Shannon K
- Faraone, Stephen V
- Hinney, Anke
- Hebebrand, Johannes
- Nigg, Joel T
- Wilmot, Beth
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Mooney, M. A., McWeeney, S. K., Faraone, S. V., Hinney, A., Hebebrand, J., Nigg, J. T., & Wilmot, B. (2016). Pathway analysis in attention deficit hyperactivity disorder: An ensemble approach. American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 171(6), 815–826. https://doi.org/10.1002/ajmg.b.32446
