Publication: Impact of 123 I-MIBG scintigraphy on clinical decision making in pheochromocytoma and paraganglioma
Impact of 123 I-MIBG scintigraphy on clinical decision making in pheochromocytoma and paraganglioma
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Rao, D., van Berkel, A., Piscaer, I., Young, W. F., Gruber, L., Deutschbein, T., Fassnacht, M., Beuschlein, F., Spyroglou, A., Prejbisz, A., Hanus, K., Eisenhofer, G., Manelli, M., Canu, L., Lenders, J. W. M., Bancos, I., & Timmers, H. J. L. M. (2019). Impact of 123 I-MIBG scintigraphy on clinical decision making in pheochromocytoma and paraganglioma. Journal of Clinical Endocrinology & Metabolism, 104(9), 3812–3820. https://doi.org/10.1210/jc.2018-02355
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CONTEXT: Cross sectional imaging with computed tomography (CT) or magnetic resonance imaging (MRI) is regarded as a first-choice modality for tumor localization in patients with pheochromocytoma and paraganglioma (PPGL). 123I-labeled metaiodobenzylguanidine (123I-MIBG) is widely used for functional imaging but the added diagnostic value is controversial. OBJECTIVE: To establish the virtual impact of adding 123I-MIBG scintigraphy to CT or MRI on diagnosis and treatment of PPGL. DESIGN International multicenter retrospective study. INT
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Rao, D., van Berkel, A., Piscaer, I., Young, W. F., Gruber, L., Deutschbein, T., Fassnacht, M., Beuschlein, F., Spyroglou, A., Prejbisz, A., Hanus, K., Eisenhofer, G., Manelli, M., Canu, L., Lenders, J. W. M., Bancos, I., & Timmers, H. J. L. M. (2019). Impact of 123 I-MIBG scintigraphy on clinical decision making in pheochromocytoma and paraganglioma. Journal of Clinical Endocrinology & Metabolism, 104(9), 3812–3820. https://doi.org/10.1210/jc.2018-02355