Publication: Offensive Behavior, Striatal Glutamate Metabolites, and Limbic-Hypothalamic-Pituitary-Adrenal Responses to Stress in Chronic Anxiety
Offensive Behavior, Striatal Glutamate Metabolites, and Limbic-Hypothalamic-Pituitary-Adrenal Responses to Stress in Chronic Anxiety
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Ullmann, E., Chrousos, G., Perry, S. W., Wong, M.-L., Licinio, J., Bornstein, S. R., Tseilikman, O., Komelkova, M., Lapshin, M. S., Vasilyeva, M., Zavjalov, E., Shevelev, O., Khotskin, N., Koncevaya, G., Khotskina, A. S., Moshkin, M., Cherkasova, O., Sarapultsev, A., Ibragimov, R., … Yehuda, R. (2020). Offensive Behavior, Striatal Glutamate Metabolites, and Limbic-Hypothalamic-Pituitary-Adrenal Responses to Stress in Chronic Anxiety. International Journal of Molecular Sciences, 21(20), 7440. https://doi.org/10.3390/ijms21207440
Abstract
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Variations in anxiety-related behavior are associated with individual allostatic set-points in chronically stressed rats. Actively offensive rats with the externalizing indicators of sniffling and climbing the stimulus and material tearing during 10 days of predator scent stress had reduced plasma corticosterone, increased striatal glutamate metabolites, and increased adrenal 11-dehydrocorticosterone content compared to passively defensive rats with the internalizing indicators of freezing and grooming, as well as to controls without
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Ullmann, E., Chrousos, G., Perry, S. W., Wong, M.-L., Licinio, J., Bornstein, S. R., Tseilikman, O., Komelkova, M., Lapshin, M. S., Vasilyeva, M., Zavjalov, E., Shevelev, O., Khotskin, N., Koncevaya, G., Khotskina, A. S., Moshkin, M., Cherkasova, O., Sarapultsev, A., Ibragimov, R., … Yehuda, R. (2020). Offensive Behavior, Striatal Glutamate Metabolites, and Limbic-Hypothalamic-Pituitary-Adrenal Responses to Stress in Chronic Anxiety. International Journal of Molecular Sciences, 21(20), 7440. https://doi.org/10.3390/ijms21207440