Sex-related differences in postoperative complications following elective craniotomy for intracranial lesions: An observational study

Brandi, Giovanna; Stumpo, Vittorio; Gilone, Marco; Tosic, Lazar; Sarnthein, Johannes; Staartjes, Victor E; Wang, Sophie Shih-Yüng; van Niftrik, Bas; Regli, Luca; Keller, Emanuela; Serra, Carlo

doi:10.1097/md.0000000000029267

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Brandi, G., Stumpo, V., Gilone, M., Tosic, L., Sarnthein, J., Staartjes, V. E., Wang, S. S.-Y., van Niftrik, B., Regli, L., Keller, E., & Serra, C. (2022). Sex-related differences in postoperative complications following elective craniotomy for intracranial lesions: An observational study. Medicine, 101(27), e29267. https://doi.org/10.1097/md.0000000000029267

Abstract

Introduction: The integration of sex-related differences in neurosurgery is crucial for new, possible sex-specific, therapeutic approaches. In neurosurgical emergencies, such as traumatic brain injury and aneurysmal subarachnoid hemorrhage, these differences have been investigated. So far, little is known concerning the impact of sex on frequency of postoperative complications after elective craniotomy. This study investigates whether sex-related differences exist in frequency of postoperative complications in patients who underwent e