Publication: T cell regulation in microgravity - the current knowledge from in vitro experiments con-ducted in space, parabolic flights and ground-based facilities
T cell regulation in microgravity - the current knowledge from in vitro experiments con-ducted in space, parabolic flights and ground-based facilities
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Hauschild, S., Tauber, S., Lauber, B., Thiel, C. S., Layer, L. E., & Ullrich, O. (2014). T cell regulation in microgravity - the current knowledge from in vitro experiments con-ducted in space, parabolic flights and ground-based facilities. Acta Astronautica, 104(1), 365–377. https://doi.org/10.1016/j.actaastro.2014.05.019
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Dating back to the Apollo and Skylab missions, it has been reported that astronauts suffered from bacterial and viral infections during space flight or after returning to Earth. Blood analyses revealed strongly reduced capability of human lymphocytes to become active upon mitogenic stimulation. Since then, a large number of in vitro studies on human immune cells have been conducted in space, in parabolic flights, and in ground-based facilities. It became obvious that microgravity affects cell morphology and important cellular function
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Hauschild, S., Tauber, S., Lauber, B., Thiel, C. S., Layer, L. E., & Ullrich, O. (2014). T cell regulation in microgravity - the current knowledge from in vitro experiments con-ducted in space, parabolic flights and ground-based facilities. Acta Astronautica, 104(1), 365–377. https://doi.org/10.1016/j.actaastro.2014.05.019