Publication: Neurological management and work-up of neurotoxicity associated with CAR T cell therapy
Neurological management and work-up of neurotoxicity associated with CAR T cell therapy
Date
Date
Date
Citations
Möhn, N., Bonda, V., Grote-Levi, L., Panagiota, V., Fröhlich, T., Schultze-Florey, C., Wattjes, M. P., Beutel, G., Eder, M., David, S., Körner, S., Höglinger, G., Stangel, M., Ganser, A., Koenecke, C., & Skripuletz, T. (2022). Neurological management and work-up of neurotoxicity associated with CAR T cell therapy. Neurological Research and Practice, 4, 1. https://doi.org/10.1186/s42466-021-00166-5
Abstract
Abstract
Abstract
Introduction: Treatment with CD19 chimeric antigen receptor (CAR) T cells is an innovative therapeutic approach for patients with relapsed/refractory diffuse large B cell lymphoma (r/rDLBCL) and B-lineage acute lymphoblastic leukemia (r/rALL). However, convincing therapeutic response rates can be accompanied by cytokine release syndrome (CRS) and severe neurotoxicity termed immune effector cell-associated neurotoxicity syndrome (ICANS).
Methods: Single center, prospective observational study of fifteen consecutive r/r DLBCL patients
Additional indexing
Creators (Authors)
Volume
Volume
Volume
Page range/Item number
Page range/Item number
Page range/Item number
Item Type
Item Type
Item Type
In collections
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Keywords
Language
Language
Language
Publication date
Publication date
Publication date
Date available
Date available
Date available
ISSN or e-ISSN
ISSN or e-ISSN
ISSN or e-ISSN
OA Status
OA Status
OA Status
Free Access at
Free Access at
Free Access at
Publisher DOI
Citations
Möhn, N., Bonda, V., Grote-Levi, L., Panagiota, V., Fröhlich, T., Schultze-Florey, C., Wattjes, M. P., Beutel, G., Eder, M., David, S., Körner, S., Höglinger, G., Stangel, M., Ganser, A., Koenecke, C., & Skripuletz, T. (2022). Neurological management and work-up of neurotoxicity associated with CAR T cell therapy. Neurological Research and Practice, 4, 1. https://doi.org/10.1186/s42466-021-00166-5
