Arabidopsis translation initiation factor binding protein CBE1 negatively regulates accumulation of the NADPH oxidase respiratory burst oxidase homolog D

George, Jeoffrey; Stegmann, Martin; Monaghan, Jacqueline; Bailey-Serres, Julia; Zipfel, Cyril

doi:10.5167/uzh-235288

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George, J., Stegmann, M., Monaghan, J., Bailey-Serres, J., & Zipfel, C. (2023). Arabidopsis translation initiation factor binding protein CBE1 negatively regulates accumulation of the NADPH oxidase respiratory burst oxidase homolog D. Journal of Biological Chemistry, 299(8), 105018. https://doi.org/10.1016/j.jbc.2023.105018

Abstract

Cell surface pattern recognition receptors sense invading pathogens by binding microbial or endogenous elicitors to activate plant immunity. These responses are under tight control to avoid excessive or untimely activation of cellular responses, which may otherwise be detrimental to host cells. How this fine-tuning is accomplished is an area of active study. We previously described a suppressor screen that identified Arabidopsis thaliana mutants with regained immune signaling in the immunodeficient genetic background bak1-5, which we