Publication: Sleep EEG slow-wave activity in medicated and unmedicated children and adolescents with attention-deficit/hyperactivity disorder
Sleep EEG slow-wave activity in medicated and unmedicated children and adolescents with attention-deficit/hyperactivity disorder
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Furrer, M., Jaramillo, V., Volk, C., Ringli, M., Aellen, R., Wehrle, F. M., Pugin, F., Kurth, S., Brandeis, D., Schmid, M., Jenni, O. G., & Huber, R. (2019). Sleep EEG slow-wave activity in medicated and unmedicated children and adolescents with attention-deficit/hyperactivity disorder. Translational Psychiatry, 9(1), 324. https://doi.org/10.1038/s41398-019-0659-3
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Slow waves (1-4.5 Hz) are the most characteristic oscillations of deep non-rapid eye movement sleep. The EEG power in this frequency range (slow-wave activity, SWA) parallels changes in cortical connectivity (i.e., synaptic density) during development. In patients with attention-deficit/hyperactivity disorder (ADHD), prefrontal cortical development was shown to be delayed and global gray matter volumes to be smaller compared to healthy controls. Using data of all-night recordings assessed with high-density sleep EEG of 50 children and
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Furrer, M., Jaramillo, V., Volk, C., Ringli, M., Aellen, R., Wehrle, F. M., Pugin, F., Kurth, S., Brandeis, D., Schmid, M., Jenni, O. G., & Huber, R. (2019). Sleep EEG slow-wave activity in medicated and unmedicated children and adolescents with attention-deficit/hyperactivity disorder. Translational Psychiatry, 9(1), 324. https://doi.org/10.1038/s41398-019-0659-3