Publication: Monitoring notch signaling-associated activation of stem cell niches within injured dental pulp
Monitoring notch signaling-associated activation of stem cell niches within injured dental pulp
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Mitsiadis, T. A., Catón, J., Pagella, P., Orsini, G., & Jimenez-Rojo, L. (2017). Monitoring notch signaling-associated activation of stem cell niches within injured dental pulp. Frontiers in Physiology, 8, 372. https://doi.org/10.3389/fphys.2017.00372
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Dental pulp stem/progenitor cells guarantee tooth homeostasis, repair and regeneration throughout life. The decision between renewal and differentiation of these cells is influenced by physical and molecular interactions with stromal cells and extracellular matrix molecules forming the specialized microenvironment of dental pulp stem cell niches. Here we study the activation of putative pulp niches after tooth injury through the upregulation of Notch signaling pathway. Notch1, Notch2, and Notch3 molecules were used as markers of denta
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Mitsiadis, T. A., Catón, J., Pagella, P., Orsini, G., & Jimenez-Rojo, L. (2017). Monitoring notch signaling-associated activation of stem cell niches within injured dental pulp. Frontiers in Physiology, 8, 372. https://doi.org/10.3389/fphys.2017.00372