Publication: Renal perfusion with histidine-tryptophan-ketoglutarate compared with Ringer's solution in patients undergoing thoracoabdominal aortic open repair
Renal perfusion with histidine-tryptophan-ketoglutarate compared with Ringer's solution in patients undergoing thoracoabdominal aortic open repair
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Kahlberg, A., Tshomba, Y., Baccellieri, D., Bertoglio, L., Rinaldi, E., Ardita, V., Colombo, E., Moscato, U., Melissano, G., & Chiesa, R. (2023). Renal perfusion with histidine-tryptophan-ketoglutarate compared with Ringer’s solution in patients undergoing thoracoabdominal aortic open repair. Journal of Thoracic and Cardiovascular Surgery, 165(2), 569-579.e5. https://doi.org/10.1016/j.jtcvs.2021.02.090
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OBJECTIVE
The objective of this study was to compare the efficacy of renal perfusion with Custodiol (Dr Franz-Kohler Chemie GmbH, Bensheim, Germany) versus enriched Ringer's solution for renal protection in patients undergoing open thoracoabdominal aortic aneurysm (TAAA) repair.
METHODS
Ninety consecutive patients scheduled for elective open TAAA repair were enrolled between 2015 and 2017 in a single-center, phase IV, prospective, parallel, randomized, double-blind trial (the CUstodiol versus RInger: whaT Is the Best Agent [CURITIB
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Kahlberg, A., Tshomba, Y., Baccellieri, D., Bertoglio, L., Rinaldi, E., Ardita, V., Colombo, E., Moscato, U., Melissano, G., & Chiesa, R. (2023). Renal perfusion with histidine-tryptophan-ketoglutarate compared with Ringer’s solution in patients undergoing thoracoabdominal aortic open repair. Journal of Thoracic and Cardiovascular Surgery, 165(2), 569-579.e5. https://doi.org/10.1016/j.jtcvs.2021.02.090