Publication: Modelling anthelmintic resistance by extending eggCounts package to allow individual efficacy
Modelling anthelmintic resistance by extending eggCounts package to allow individual efficacy
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Wang, C., Torgerson, P. R., Kaplan, R. M., George, M. M., & Furrer, R. (2018). Modelling anthelmintic resistance by extending eggCounts package to allow individual efficacy. International Journal for Parasitology: Drugs and Drug Resistance, 8(3), 386–393. https://doi.org/10.1016/j.ijpddr.2018.07.003
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The same anthelmintic treatment can have variable efficacy on individual animals even if the parasite population is homogenously susceptible. An extension of the R package eggCounts is proposed to take individual efficacy into account using a Bayesian hierarchical model. A simulation study is conducted to compare the performance of five different methods on estimating faecal egg count reduction and its uncertainty interval. Simulation results showed the individual efficacy model offered robust inference to two different data simulatio
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- Wang, Craig
- Torgerson, Paul R
- Kaplan, Ray M
- George, Melissa M
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Citations
Wang, C., Torgerson, P. R., Kaplan, R. M., George, M. M., & Furrer, R. (2018). Modelling anthelmintic resistance by extending eggCounts package to allow individual efficacy. International Journal for Parasitology: Drugs and Drug Resistance, 8(3), 386–393. https://doi.org/10.1016/j.ijpddr.2018.07.003
