Publication: Comparative Ultrastructural and Stereological Analyses of Unruptured and Ruptured Saccular Intracranial Aneurysms
Comparative Ultrastructural and Stereological Analyses of Unruptured and Ruptured Saccular Intracranial Aneurysms
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Korkmaz, E., Kleinloog, R., Verweij, B. H., Allijn, I. E., Hekking, L. H. P., Regli, L., Rinkel, G. J. E., Ruigrok, Y. M., & Andries Post, J. (2017). Comparative Ultrastructural and Stereological Analyses of Unruptured and Ruptured Saccular Intracranial Aneurysms. Journal of Neuropathology and Experimental Neurology, 76(10), 908–916. https://doi.org/10.1093/jnen/nlx075
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Abstract
Insight into processes leading to rupture of intracranial aneurysms (IAs) may identify biomarkers for rupture or lead to management strategies reducing the risk of rupture. We characterized and quantified (ultra)structural differences between unruptured and ruptured aneurysmal walls. Six unruptured and 6 ruptured IA fundi were resected after microsurgical clipping and analyzed by correlative light microscopy for quantitative analysis (proportion of the vessel wall area) and transmission electron microscopy for qualitative ultrastructu
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- Korkmaz, Emine
- Kleinloog, Rachel
- Verweij, Bon H
- Allijn, Iris E
- Hekking, Liesbeth H P
- Regli, Luca
- Rinkel, Gabriel J E
- Ruigrok, Ynte M
- Andries Post, Jan
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Korkmaz, E., Kleinloog, R., Verweij, B. H., Allijn, I. E., Hekking, L. H. P., Regli, L., Rinkel, G. J. E., Ruigrok, Y. M., & Andries Post, J. (2017). Comparative Ultrastructural and Stereological Analyses of Unruptured and Ruptured Saccular Intracranial Aneurysms. Journal of Neuropathology and Experimental Neurology, 76(10), 908–916. https://doi.org/10.1093/jnen/nlx075
