Publication: Neural functions of calcineurin in synaptic plasticity and memory
Neural functions of calcineurin in synaptic plasticity and memory
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Baumgärtel, K., & Mansuy, I. M. (2012). Neural functions of calcineurin in synaptic plasticity and memory. Learning & Memory, 19(9), 375–384. https://doi.org/10.1101/lm.027201.112
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Major brain functions depend on neuronal processes that favor the plasticity of neuronal circuits while at the same time maintaining their stability. The mechanisms that regulate brain plasticity are complex and engage multiple cascades of molecular components that modulate synaptic efficacy. Protein kinases (PKs) and phosphatases (PPs) are among the most important of these components that act as positive and negative regulators of neuronal signaling and plasticity, respectively. In these cascades, the PP protein phosphatase 2B or cal
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Baumgärtel, K., & Mansuy, I. M. (2012). Neural functions of calcineurin in synaptic plasticity and memory. Learning & Memory, 19(9), 375–384. https://doi.org/10.1101/lm.027201.112