Publication: Smooth muscle proteins from Hirschsprung's disease facilitates stem cell differentiation
Smooth muscle proteins from Hirschsprung's disease facilitates stem cell differentiation
Date
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Citations
Hagl, C. I., Heumüller, S., Klotz, M., Subotic, U., Wessel, L., & Schäfer, K. H. (2012). Smooth muscle proteins from Hirschsprung’s disease facilitates stem cell differentiation. Pediatric Surgery International, 28(2), 135–142. https://doi.org/10.1007/s00383-011-3010-5
Abstract
Abstract
Abstract
BACKGROUND AND AIMS:
The transplantation of neural crest derived stem cells (NCSC's) is a potent alternative for the treatment of Hirschsprung's disease (HSCR). Cells to be transplanted should find an appropriate microenvironment to survive and differentiate. To investigate the quality of this microenvironment, effects of HSCR-smooth-muscle-protein extracts upon NCSC's were studied in vitro. METHODS:
Postnatal human gut from children undergoing colonic resection due to HSCR was divided in segments. Smooth muscle was dissected and ho
Additional indexing
Creators (Authors)
- Hagl, C I
- Heumüller, S
- Klotz, M
- Subotic, U
- Wessel, L
- Schäfer, K H
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Citations
Hagl, C. I., Heumüller, S., Klotz, M., Subotic, U., Wessel, L., & Schäfer, K. H. (2012). Smooth muscle proteins from Hirschsprung’s disease facilitates stem cell differentiation. Pediatric Surgery International, 28(2), 135–142. https://doi.org/10.1007/s00383-011-3010-5
