Publication: Broad Range Eubacterial Polymerase Chain Reaction of Cerebrospinal Fluid Reduces the Time to Exclusion of and Costs Associated with Ventriculostomy-Related Infection in Hemorrhagic Stroke
Broad Range Eubacterial Polymerase Chain Reaction of Cerebrospinal Fluid Reduces the Time to Exclusion of and Costs Associated with Ventriculostomy-Related Infection in Hemorrhagic Stroke
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Pietrzko, E., Bögli, S., Frick, K., Ebner-Dietler, S., Capone, C., Imkamp, F., Koliwer-Brandl, H., Müller, N., Keller, E., & Brandi, G. (2024). Broad Range Eubacterial Polymerase Chain Reaction of Cerebrospinal Fluid Reduces the Time to Exclusion of and Costs Associated with Ventriculostomy-Related Infection in Hemorrhagic Stroke. Neurocritical Care, 40, 1109–1116. https://doi.org/10.1007/s12028-023-01888-x
Abstract
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Abstract
BACKGROUND: Patients with hemorrhagic stroke and an external ventricular drain in situ are at risk for ventriculostomy-related-infections (VRI). Because of the contamination of the cerebrospinal fluid (CSF) with blood and the high frequency of false negative CSF culture, the diagnosis of VRI remains challenging. This study investigated the introduction of CSF broad range eubacterial polymerase chain reaction (ePCR) and its effect on frequency and duration of antibiotic therapy for VRI, neurocritical care unit (NCCU) length of stay, re
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- Pietrzko, Elisabeth
- Bögli, Stefan
- Frick, Katja
- Ebner-Dietler, Sabeth
- Capone, Crescenzo
- Imkamp, Frank
- Koliwer-Brandl, Hendrik
- Müller, Nicolas
- Brandi, Giovanna
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Pietrzko, E., Bögli, S., Frick, K., Ebner-Dietler, S., Capone, C., Imkamp, F., Koliwer-Brandl, H., Müller, N., Keller, E., & Brandi, G. (2024). Broad Range Eubacterial Polymerase Chain Reaction of Cerebrospinal Fluid Reduces the Time to Exclusion of and Costs Associated with Ventriculostomy-Related Infection in Hemorrhagic Stroke. Neurocritical Care, 40, 1109–1116. https://doi.org/10.1007/s12028-023-01888-x
