Publication: Assessing the potential impact of transmission during prolonged viral shedding on the effect of lockdown relaxation on COVID-19
Assessing the potential impact of transmission during prolonged viral shedding on the effect of lockdown relaxation on COVID-19
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Tepekule, B., Hauser, A., Kachalov, V. N., Andresen, S., Scheier, T., Schreiber, P. W., Günthard, H. F., & Kouyos, R. D. (2021). Assessing the potential impact of transmission during prolonged viral shedding on the effect of lockdown relaxation on COVID-19. PLoS Computational Biology, 17, e1008609. https://doi.org/10.1371/journal.pcbi.1008609
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A key parameter in epidemiological modeling which characterizes the spread of an infectious disease is the generation time, or more generally the distribution of infectiousness as a function of time since infection. There is increasing evidence supporting a prolonged viral shedding window for COVID-19, but the transmissibility in this phase is unclear. Based on this, we develop a generalized Susceptible-Exposed-Infected-Resistant (SEIR) model including an additional compartment of chronically infected individuals who can stay infectio
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Tepekule, B., Hauser, A., Kachalov, V. N., Andresen, S., Scheier, T., Schreiber, P. W., Günthard, H. F., & Kouyos, R. D. (2021). Assessing the potential impact of transmission during prolonged viral shedding on the effect of lockdown relaxation on COVID-19. PLoS Computational Biology, 17, e1008609. https://doi.org/10.1371/journal.pcbi.1008609