Publication: Genome-wide association scan of the time to onset of attention deficit hyperactivity disorder
Genome-wide association scan of the time to onset of attention deficit hyperactivity disorder
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Lasky-Su, J., Anney, R. J. L., Neale, B. M., Franke, B., Zhou, K., Maller, J. B., Vasquez, A. A., Chen, W., Asherson, P., Buitelaar, J., Banaschewski, T., Ebstein, R., Gill, M., Miranda, A., Mulas, F., Oades, R. D., Roeyers, H., Rothenberger, A., Sergeant, J., … Faraone, S. V. (2008). Genome-wide association scan of the time to onset of attention deficit hyperactivity disorder. American Journal of Medical Genetics. Part B, 147B(8), 1355–1358. https://doi.org/10.1002/ajmg.b.30869
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A time-to-onset analysis for family-based samples was performed on the genomewide association (GWAS) data for attention deficit hyperactivity disorder (ADHD) to determine if associations exist with the age at onset of ADHD. The initial dataset consisted of 958 parent-offspring trios that were genotyped on the Perlegen 600,000 SNP array. After data cleaning procedures, 429,981 autosomal SNPs and 930 parent-offspring trios were used found suitable for use and a family-based logrank analysis was performed using that age at first ADHD sym
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Lasky-Su, J., Anney, R. J. L., Neale, B. M., Franke, B., Zhou, K., Maller, J. B., Vasquez, A. A., Chen, W., Asherson, P., Buitelaar, J., Banaschewski, T., Ebstein, R., Gill, M., Miranda, A., Mulas, F., Oades, R. D., Roeyers, H., Rothenberger, A., Sergeant, J., … Faraone, S. V. (2008). Genome-wide association scan of the time to onset of attention deficit hyperactivity disorder. American Journal of Medical Genetics. Part B, 147B(8), 1355–1358. https://doi.org/10.1002/ajmg.b.30869